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Salary
$172k – $233k per year
Location
Hybrid (Cambridge, United States)
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Architect
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Confirmed on the employer's own hiring board on Oct 25, 2026. First seen by Alion on Sep 14, 2026.

Overview
Company
Impact
Profile match
Alnylam Pharmaceuticals is a biopharmaceutical company headquartered in Cambridge, Massachusetts, that develops and commercialises RNA interference therapeutics for rare and common diseases, including ATTR amyloidosis and acute hepatic porphyria. Founded in Cambridge in 2002 and listed on the Nasdaq, it has six approved medicines available in more than 70 countries, a manufacturing site in Norton, Massachusetts, a European base in Maidenhead and an affiliate in Tokyo. It hires research and biology scientists, quality control analysts, clinical science and regulatory affairs staff, field reimbursement and key account managers, and IT, cyber defense and HR technology leaders.

Associate Director, Laboratory Informatics Platforms

Cambridge, MA

Overview

Alnylam is seeking an Associate Director, Laboratory Informatics Platforms to lead the strategy, roadmap, delivery, and operational stewardship of core laboratory informatics capabilities across Research and Early Development (ReDev) and CMC. The role will own all aspects of product and technology lifecycle for electronic lab notebook (ELN), sample management, entity registration, workflow orchestration, and instrument data capture capabilities for ReDev and CMC.  The role with work closely with stakeholders in scientific and technical operations and technology product owners in IT Quality Technology (e.g., LIMS), to translate business needs into scalable, compliant, and fit-for-purpose digital solutions that improve data quality, traceability, workflow efficiency, and user experience across ReDev, CMC, and QC environments to realize business priorities. The platform landscape developed by the Laboratory Informatics Platforms lead must also efficiently support target architecture, secure solution integration, future analytics and data exploration, and AI-enabled use cases.

Key Responsibilities

  • Lead platform strategy and delivery. Translate scientific and technical operations needs into roadmaps, requirements, priorities, releases, change controls, and lifecycle standards for scalable laboratory solutions across ReDev and CMC.
  • Integrate laboratory workflows and data. Connect experiments, samples, entities, instrument data, and results across ELN and related platforms. Align master data, vocabularies, data models, orchestration, and integration patterns to improve traceability, efficiency, usability, and downstream analytics.
  • Coordinate cross-functional delivery. Partner with Lab Computing and Facilities Technology on instrument connectivity, deployment, and support; Quality Technology on QC requirements, compliance, and LIMS integration; and Data and AI, Infrastructure, Security, business teams, and vendors on secure, scalable enterprise alignment.
  • Ensure compliance and sustainability. Work with Quality and validation teams to meet compliance and data integrity standards, support validated system lifecycle practices, and maintain audit readiness and long-term platform sustainability.

Required Qualifications

  • Bachelor’s degree in computer science, engineering, life sciences, or a related field, or equivalent experience
  • 10-12 years of laboratory informatics / biotechnology / pharmaceutical experience in Research and/or CMC areas
  • Proven ability to lead cross-functional business, IT, and vendor teams to translate business needs into system designs and solutions which achieve key business outcomes
  • Experience developing strategic roadmaps and delivering / managing the lifecycle of ELN, sample management, entity registration, or related laboratory platforms
  • Experience delivering laboratory digital solutions governed by GxP, 21 CFR Part 11, computer system validation (CSV), and ALCOA+ data integrity principles
  • Strong cross-functional leadership, communication, and stakeholder engagement skills; track record of effective technology product decision making

Preferred Qualifications

  • Advanced degree in life sciences, engineering, computer science, or a related field
  • Experience with laboratory workflow orchestration, cross-platform integration, instrument data capture, scientific data standards and data models, and SaaS platform ecosystems
  • Experience in RNA interference (RNAi), oligonucleotide, or other advanced-modality environments
  • Experience integrating laboratory platforms with a QC LIMS

About Alnylam

We are the leader in RNAi therapeutics - a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

Before applying, please review Alnylam's Candidate  Privacy Notice  regarding how Alnylam handles Personal Data you provide with your application for employment.

The pay range below reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).

Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.

Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website:  https://www.alnylam.com/careers

U.S. Pay Range

$172,200—$233,000 USD

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