368,657open jobs
9,442companies
50,883added this week
Browse all
Salary
$133k – $266k per year (Estimated)
Location
In office (San Francisco)
Seniority
Middle · 3+ years exp
Employment
Full-Time
Overview
Company
Impact
Profile match

Founding Engineer, Backend & Infrastructure

About Backbone

Care should be paid for the moment it’s delivered. At Backbone, we’re making that possible for the first time by building the clinical AI layer for healthcare payments.

Today, U.S. healthcare wastes more than $350B yearly on administrative work that has nothing to do with patient care: prior authorizations, denials, appeals, and the staff hired on both sides of the aisle to adjudicate and determine payment for services rendered. As a result, patient care is delayed, clinicians burn out, margins crater, and hundreds of billions of dollars that should be funding care end up funding the friction itself.

Backbone is dismantling this friction, building intelligent financial rails atop clinical AI research to facilitate instant payments between payers and providers. We're backed by Andreessen Horowitz (a16z), Lightspeed, Hanabi, and a roster of operators and clinicians who have built and run the largest payers, providers, and healthcare technology platforms in the country. Our founder/CEO, Manan Shah, holds a BS/MS in Math & CS from Stanford and led ML infrastructure at Sequoia-backed Kumo AI, where he built graph neural networks serving DoorDash, Reddit, and Coinbase.

Backbone’s revenue is growing quickly, customer demand is outpacing our team, and the road ahead is bright.

What you’ll do

As a founding engineer, you’ll own the systems that make Backbone work: chart ingestion, document processing, claims workflows, browser and computer-use automation, payer portal navigation, orchestration, queues, reliability, auditability, and the infrastructure needed to scale from thousands of charts and claims to hundreds of thousands.

You will:

  • Build and scale the distributed systems that power Backbone’s clinical and financial workflow; own backend services across chart data, claims data, authorization workflows, denial workflows, and payer/provider integrations

  • Build orchestration infrastructure for long-running, failure-prone workflows across EHRs, practice management systems, clearinghouses, and payer portals

  • Work on browser-use and computer-use systems that navigate complex medical software and payer portals

  • Design reliable systems for messy healthcare data: scanned charts, PDFs, structured claims, unstructured notes, attachments, policies, and operational state

  • Build observability, retry, audit, and human-in-the-loop infrastructure for high-stakes production workflows

  • Partner with product and research engineers to take new clinical intelligence capabilities into production, and set the engineering patterns that future engineers will inherit

What we’re looking for

  • 3+ years of professional software engineering experience shipping production systems end-to-end

  • Generalist range across backend, data, and ML, alongside real LLM experience in production

  • Comfort with distributed systems, microservices, queues, workflow engines, data pipelines, or large-scale backend infrastructure

Healthcare experience is helpful, but not required. Curiosity, rigor, and taste matter more.

Why join

This is a chance to join early and help define both the product and the engineering culture.

You’ll work on hard, practical problems: turning fragmented healthcare workflows into software that actually helps people do their jobs faster and better. Your work will touch product decisions, system architecture, user experience, and the core automation engine behind Backbone.

We offer competitive compensation, meaningful ownership, and the opportunity to build foundational technology in a massive, broken, high-impact industry.

Free account
Stop reading job ads. Get the ones that fit.
One free account turns this page into a shortlist built around your stack, your level and your pay.
Match on every job. Stack, seniority, pay and location, scored against your profile.
368,657 open roles. Read straight off company career pages, refreshed every day.
Unlimited applications. Every one you send is tracked in one place, on-site or on a company board.
3 tailored CVs a month. Rewritten for the exact job you are applying to. Included free.
Create a free account
Free forever. No card. Under a minute.

Your match

How well do you fit this role?
Two answers are enough for a real match. No account needed.
Check my fit
Answers stay in this browser until you create an account.

Recommended for you based on this role

Similar stack
Same company
San Francisco
$28k – $53k per year (Estimated) • In office • Full-Time • Rostov-on-Don
AI/ML
LLM
RAG
Apply
$21k per year • In office • Contractor • Yekaterinburg
Python
SQL
Python
FastAPI
Flask
AI/ML
Claude
Claude Code
Embeddings
Function Calling
LLM
RAG
OpenAI
OpenAI Codex
Structured Outputs
DevOps
Docker
Git
Apply
$140k – $225k per year • Remote • Full-Time • 5+ years exp • Seattle
Python
Lua
Python
FastAPI
Celery
Pydantic
SQLAlchemy
Databases
pgvector
PostgreSQL
Redis
AI/ML
LLM
RAG
Hybrid Search
Reranking
Anthropic
LLM Evaluation
LLM Guardrails
OpenAI
Model Context Protocol
DevOps
OpenTelemetry
Apply
$98k – $132k per year • Remote • Full-Time • 5+ years exp • Bachelor's Degree
Python
R
SQL
Databases
Databricks
Snowflake
AI/ML
Embeddings
LangChain
LangGraph
LLM
NumPy
Pandas
Scikit-learn
Spark
TensorFlow
Transformers
Hugging Face
RAG
Analytics
Matplotlib
Seaborn
Apply
$98k – $132k per year • Remote • Full-Time • 5+ years exp • Bachelor's Degree
Python
R
SQL
Databases
Databricks
Snowflake
AI/ML
Embeddings
LangChain
LangGraph
LLM
NumPy
Pandas
Scikit-learn
Spark
TensorFlow
Transformers
Hugging Face
RAG
Analytics
Matplotlib
Seaborn
Apply
$170k – $220k per year • Equity 1–2.8% • In office • Full-Time • 3+ years exp • San Francisco
Python
SQL
Python
Django
AI/ML
AI Agents
Context Engineering
LLM
LLM Evaluation
RAG
Apply
$173k – $314k per year • In office • Full-Time • 12+ years exp • Bachelor's Degree • San Francisco
Apex
JavaScript
Node JS
Python
SQL
TypeScript
Apex
Lightning Web Components
AI/ML
Agentforce
AI Agents
Claude
Claude Code
Copilot
Cursor
LLM
RAG
DevOps
AWS
Azure
CI/CD
Docker
GCP
GitHub
Grafana
gRPC
Kubernetes
New Relic
Prometheus
Splunk
Marketing
Salesforce
QA
Cypress
JMeter
k6
Locust
Playwright
Postman
Rest-Assured
Selenium
Apply
Senior ML Engineer 2 hours ago
$149k – $224k per year • In office • Full-Time • 5+ years exp • Master's Degree • San Francisco • Washington • Palo Alto
Python
Python
pySpark
Databases
Apache Kafka
AI/ML
AI Agents
Agentforce
Airflow
Anomaly Detection
Feature Store
Flink
Ray
Red Teaming
Spark
DevOps
CI/CD
Docker
Kubernetes
Cybersecurity
MITRE ATT&CK
Marketing
Salesforce
Apply
In office • Internship • 1+ year exp • Bachelor's Degree • San Francisco
Go
JavaScript
Ruby
Scala
Apply
$360k – $530k per year • In office • Full-Time • Bachelor's Degree • San Francisco
MATLAB
Python
MATLAB
Simulink
AI/ML
OpenAI
Robotics
Digital Twin
Apply
See all jobs
This is one of many
368,657 more open roles from verified company boards, updated every day.