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Salary
≈ $74k – $140k per year (Estimated)
Location
In office (Mainz)
Seniority
Senior · 5+ years exp

Confirmed on the employer's own hiring board on Oct 9, 2026. First seen by Alion on Sep 30, 2026.

Overview
Company
Impact
Profile match
BioNTech is a German biotechnology company founded in Mainz in 2008 by the physician-scientists Ugur Sahin and Ozlem Tureci to develop individualised cancer immunotherapies using messenger RNA. Its mRNA platform, refined over a decade on oncology programmes, was redirected in early 2020 to produce Comirnaty with Pfizer, the first COVID-19 vaccine authorised in the West and the source of tens of billions of euros in revenue. The company has reinvested that windfall into its original mission, running a broad clinical pipeline of mRNA cancer vaccines, individualised neoantigen therapies and bispecific antibodies including the closely watched BNT327 programme.

Mainz, Germany | full time | Job ID: 11788

About the Role:

BioNTech SE currently runs a variety of digitalization projects including SAP ERP, MES and LIMS systems. As part of our growth activities our digital solutions will be extended by a global LIMS Platform for the research and development/ scientific part at BioNTech and we want to increase our efforts to bring more digital solutions in to support our R&D processes. Thus, a global R&D digital ecosystem including various capabilities is currently rolled out to our labs.

As Senior System Engineer, you will be part of the team that builds, deploys and runs software solutions to support the digitalization of R&D labs. You will be taking over technical responsibility in all phases of the lifecycle of assigned software systems, from ideation over implementation to maintenance. In the solutioning phase, it is the responsibility to identify the most suitable solution for the underlying technical needs in alignment with the respective governance and frame conditions. As the owner of the applications, the Senior System Engineer Service aligns all activities with the stakeholders (business partners, domain architect) and makes sure that the solutions meet the user and architecture requirements.

With a very high level of technical expertise and strategic competence in R&D Lab Systems, you work cross functional through the application and project life cycle to ensure consistent processes delivered according to our standards for the designated application area(s).

Your Contribution:

  • Solution Design: Identify the most suitable technical solutions for complex business needs, ensuring alignment with IT governance and strategic frameworks.
  • Stakeholder Management: Act as the central interface between business partners, technical teams, and domain architects to ensure solutions meet user requirements and corporate standards.
  • Strategic Advisory: Leverage your deep expertise in R&D lab systems (e.g., ELN, SDMS, Automation, Data Evaluation) to provide technical insights and drive the application roadmap.
  • Project Delivery: Lead the technical change management and ensure the successful, compliant delivery of assigned software projects.
  • Continuous Improvement: Ensure long-term stakeholder satisfaction by maintaining a high-performing and scalable software landscape.

A Good Match:

  • Degree in Biology, Computer Science, Engineering, Pharmacy, or a related field, with at least 5 years of relevant experience in pharma, IT operations, or process management.
  • Strong technical affinity to identify best suitable technical solutions for complex challenges.
  • First-hand technical hands-on experience with System integration and related technologies (such as REST, SOAP, GraphQL), ideally using an Integration Layer such as Mulesoft is required.
  • Knowledge of scripting languages such as Python, JavaScript, or PowerShell is required; basic familiarity with modern programming languages such as Java or C# is considered a plus.
  • Understanding of common device communication standards, such as OPC UA/DA and SiLA2 appreciated.
  • Very strong communication skills with fluency in English required, and advanced proficiency in German is considered a plus.

Your Benefits:

It's our priority to support you:

  • Your flexibility: flexible hours | vacation account
  • Your growth: Digital Learning | Performance & talent development | leadership development | Apprenticeships | LinkedIn Learning
  • Your value: Your voice at the table | Culture on an equal footing | Opportunities to shape & impact | Support for your full potential
  • Your health and lifestyle: Company bike
  • Your mobility: Job ticket | Deutschlandticket
  • Your life phases: Employer-funded pension | Childcare

Apply now - We look forward to your application!

Apply to our Mainz, Germanylocation by sending us your documents via our online form. For any questions, contact our talent acquisition team on: + 49 (0) 6131-9084-1291 (Monday-Friday from 1 PM to 3 PM CET).

Job ID 11788 (please always specify if you have any questions)

By submitting your application, you acknowledge that a background check will be conducted as part of the recruitment process in accordance with applicable laws and regulations. If you are considered for the position, BioNTech will conduct the background check through our service provider ‘HireRight’. You will be informed accordingly by your BioNTech-Recruiter.

Note for applications within Europe: Please note that if you wish to claim travel expenses incurred in connection with an in-person interview, we are obliged to carry out a sanctions list check*. This is carried out by our partner, HireRight. Travel expenses will only be reimbursed if this sanctions list check does not yield any matches. Reimbursement can be made provided that the check is successfully completed.

* Your first name, surname and date of birth will be processed for the sanctions list check. The legal basis for carrying out the sanctions list check for positions at BioNTech in Europe is BioNTech’s legitimate interest. Please note that BioNTech will not carry out the sanctions list check if no travel expenses are to be reimbursed. If you do not give BioNTech your consent to the sanctions list check, your travel expenses cannot be reimbursed. This will not affect your application.

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