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Salary
≈ $143k – $298k per year (Estimated)
Location
In office (San Francisco)
Visa
H-1B filings in 12 months: 2 · for this role: 2
Employment
Full-Time

Confirmed on the employer's own hiring board on Oct 13, 2026. First seen by Alion on Oct 12, 2026. Chai Discovery scores C on the Alion truth index.

Overview
Company
Impact
Profile match
Chai Discovery is a San Francisco research company founded in 2024 that builds foundation models for molecular structure and interaction prediction. Its Chai-1 model predicts complexes of proteins, small molecules, nucleic acids and antibodies, and was released for free non-commercial use alongside a commercial offering. The company is backed by OpenAI and Thrive Capital and targets the design of antibodies and other biologics.

About Chai Discovery

Chai builds the design suite for molecules. We train frontier models that learn the underlying foundations of biochemical structure and interaction, so scientists can move faster and pursue targets that other methods cannot reach.

AI is reinventing life sciences the same way it reinvented software engineering, and Chai is at the forefront of this shift. Leading pharmaceutical companies like Eli Lilly, Pfizer, and Novartis are adopting our platform to power their drug discovery programs.

We value diverse perspectives and are ready to find greatness in unexpected places.

About the role

Build the AI platform that lets scientists direct research programs with agents. As agents become more capable, they will increasingly use Chai’s foundation models to design molecules and guide experiments. We believe scientists should be able to work at the level of the questions they want answered and delegate more of the work required to answer them; you will build the platform that makes this possible.

  • Work with scientists and researchers to define how people, agents, and models work together throughout a therapeutic research program.

  • Build products that shorten the cycle from an idea to an experiment to the next decision, while keeping scientists able to understand and direct the work.

  • Build the core abstractions for agent execution, model inference, and scientific tools so new capabilities can work together across the workspace.

About you

We look for strong software architecture and product judgment, with depth in complex applications or agent systems. You can find clear abstractions in a messy domain and build systems that hold up as their scope grows. We value a practical understanding of where agents fail and how to tell whether they’re doing useful work.

We offer

The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect & promote a culture of high velocity and ownership. We compensate our team accordingly.

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