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Salary
≈ $141k – $298k per year (Estimated)
Location
In office (San Francisco)
Visa
H-1B filings in 12 months: 2 · for this role: 2
Employment
Full-Time

Confirmed on the employer's own hiring board on Oct 17, 2026. First seen by Alion on Jun 30, 2025. Chai Discovery scores C on the Alion truth index.

Overview
Company
Impact
Profile match
Chai Discovery is a San Francisco research company founded in 2024 that builds foundation models for molecular structure and interaction prediction. Its Chai-1 model predicts complexes of proteins, small molecules, nucleic acids and antibodies, and was released for free non-commercial use alongside a commercial offering. The company is backed by OpenAI and Thrive Capital and targets the design of antibodies and other biologics.

About Chai Discovery

Chai builds the design suite for molecules. We train frontier models that learn the underlying foundations of biochemical structure and interaction, so scientists can move faster and pursue targets that other methods cannot reach.

AI is reinventing life sciences the same way it reinvented software engineering, and Chai is at the forefront of this shift. Leading pharmaceutical companies like Eli Lilly, Pfizer, and Novartis are adopting our platform to power their drug discovery programs.

We value diverse perspectives and are ready to find greatness in unexpected places.

About the role

Build the scientific workspace that helps scientists tackle harder problems in drug discovery. We believe every scientist developing new medicines should be able to use Chai’s models to make progress on their research.

  • Work directly with scientists to understand their problems and decide what to build.

  • Own the work from the first conversation through to a product they depend on, going as deep into the science, compute, models, research, and software as the problem requires.

  • Work forward deployed with our customers, ship across the stack, and refine the product and its core abstractions as you learn.

About you

We look for engineers who can make sense of messy real-world problems and build simple solutions end to end. Former founders and engineers who have owned substantial products are a particularly good fit. Familiarity with the scientific domain is not required. We value technical depth, product judgment, and a record of building things that are meaningful and useful to people.

We offer

The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect & promote a culture of high velocity and ownership. We compensate our team accordingly.

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