Senior Site Reliability Engineer

About CluePointsCluePoints is redefining how clinical trials are run. As a leading provider of Risk-Based Quality Management (RBQM) and Data Quality Oversight software, we use advanced statistics, artificial intelligence and machine learning to ensure the quality, accuracy and integrity of clinical trial data, helping life sciences organisations bring safer, more effective treatments to patients faster.

We are an ambitious, fast-growing technology scale-up with a dynamic and diverse international team representing more than 20 nationalities. Collaboration, flexibility and continuous learning are part of our DNA, and our values of Care, Passion and Smart Disruption unite us behind a shared mission: to create smarter ways to run efficient clinical trials and deliver AI-powered insights that improve human outcomes worldwide.

The Role

The Senior SRE is a senior engineering role in CluePoints' Site Reliability Engineering team, keeping the platform behind our clinical-trial software secure, available and cost-efficient. You will own significant parts of the Azure and Kubernetes estate end to end, lead technical initiatives across teams, and raise the engineering bar for the team.

What You'll Be Doing

Platform & Infrastructure

• Design, operate and evolve the Azure and AKS foundation: networking, ingress/Gateway API (Istio), WAF, DNS, certificates and patching.
• Run GitOps delivery with Argo CD and maintain the CI runner estate.
• Build and maintain Terraform modules, automated testing and validation, and self-service environment provisioning.

Reliability & Observability

• Own logging, metrics and alerting, reduce alert noise and forecast capacity.
• Lead infrastructure incident response and blameless postmortems.
• Take part in the on-call rotation.

Data & Shared Services

• Run managed databases and storage with robust backup/restore, disaster recovery and retention, including migrations and major version upgrades.
• Operate shared middleware such as secret management and job scheduling.
• Run internal engineering and AI services (LLM gateway, review and test-analysis tooling, ephemeral environments), defining contracts and supporting adoption.

Security, Cost & Leadership

• Implement platform security controls and produce audit evidence.
• Drive cloud cost optimisation.
• Lead cross-team technical initiatives, write design proposals and mentor engineers.

What You'll Need

Must Have

• 5+ years in SRE, platform or cloud infrastructure engineering, with production ownership of business-critical SaaS systems.
• Deep hands-on experience with Azure (networking, identity/RBAC, managed services) in production.
• Deep hands-on experience with Kubernetes, ideally AKS, in production.
• Strong Infrastructure as Code skills with Terraform, plus GitOps (Argo CD or similar) and CI/CD pipelines.
• Solid observability practice (Prometheus/Grafana, Elastic/Kibana or similar) and a track record of reducing alert noise and leading incidents.
• Experience operating managed databases (MySQL/PostgreSQL), including backup and DR.
• Strong scripting in Python, Go or Bash.
• Experience implementing security controls in a regulated or audited environment (ISO 27001, SOC 2; GxP a plus).
• Clear written English, sound judgement on trade-offs, and the ability to lead work across teams.

Nice to Have

• Service mesh experience (Istio, Gateway API).
• Temporal, Vault/External Secrets, KEDA or Trino.
• Experience running LLM/AI platforms.
• FinOps experience.
• Life sciences or clinical-trial industry background.

What We Offer

What We Offer - Belgium

• Health Insurance through Alan (100% hospitalisation cover, 80% ambulatory and dental)
• Mobility Budget for eco-transport, housing, or car allowance (flexible 3-pillar system)
• Group Insurance Plan with 6-12% employer pension contribution based on seniority
• Meal Vouchers (€8/day) and Eco Vouchers for sustainable purchases
• A hub-based hybrid model that blends flexibility with purpose - connecting teams through collaboration, learning, and a vibrant social culture.

Equal Opportunities & GDPR NoticeCluePoints is an equal opportunities employer. We value and respect diversity in our workforce and do not tolerate discrimination based on gender, age, disability, ethnic origin, religion, sexual orientation, or any other protected ground under Belgian law.

Personal data collected as part of your application will be processed in compliance with the EU GDPR and Belgian data protection legislation.

You have the right to access, correct, or delete your personal data at any time by contacting [email protected].