1,901,130open jobs
111,542companies
257,027added this week
Browse all
Salary
$152k – $215k per year
Location
In office (Alameda)
Seniority
Middle · 2+ years exp
Visa
H-1B filings in 12 months: 33 · for this role: 14 · green card filings: 10
Employment
Full-Time

Confirmed on the employer's own hiring board on Oct 21, 2026. First seen by Alion on Sep 22, 2026.

Overview
Company
Impact
Profile match
Exelixis is a US biotech company focused on developing oncology treatments. It markets its cancer medicines to patients, oncology providers and nurses and hires marketing directors, data management directors, account managers and IT product leads. The company is headquartered in Alameda, California, United States.
Backed by Atlas Venture

SUMMARY/JOB PURPOSE

The Engineer II - AI and Agentic is responsible for designing, building, and deploying production-grade agentic applications that automate multi-step IT and business workflows across Exelixis. This role delivers spec-driven, testable, and secure AI solutions, contributes to platform patterns and reusable components, while advancing the engineering standards.

ESSENTIAL DUTIES/RESPONSIBILITIES

  • Design and deliver end-to-end agentic applications and multi-agent workflows that automate IT and business processes.
  • Convert prototypes into hardened, production-ready services with clear specifications, modular design, robust error handling, and comprehensive test coverage.
  • Integrate LLMs, prompts, tools, APIs, and enterprise data sources (e.g., Bedrock, Databricks Mosaic AI, MCP servers) into reliable use cases.
  • Implement CI/CD pipelines, automated evaluation harnesses, observability, and artifact versioning for AI/agent workloads.
  • Author architecture notes, runbooks, SOPs, and technical documentation to support adoption, operability, and maintainability.
  • Lead prompt/spec reviews, code reviews, threat modeling exercises, and release-readiness gates.
  • Apply and evangelize secure-by-design and responsible AI principles, including data governance, privacy, and safe prompting aligned to organizational policy
  • Contribute reusable components, patterns, and internal libraries to the platform
  • Partner with product managers, security, and platform teams to translate business needs into scalable technical solutions
  • Performs other duties as assigned
  • Complies with all policies and standards

SUPERVISORY RESPONSIBILITIES

  • No supervisory responsibilities

EDUCATION/EXPERIENCE/KNOWLEDGE/SKILLS & ABILITIES

Education

  • Bachelor's degree in Computer Science, Artificial Intelligence, Data Science, Software Engineering, or a related field and 5 years of related experience; or
  • Master’s degree in Computer Science, Artificial Intelligence, Data Science, Software Engineering, or a related field and 3 year or related experience; or
  • Equivalent combination of education and experience.

Experience

  • 2 - 4 years of relevant experience in AI application, data science, automation, or related technical work, including hands-on experience building or contributing to LLM-enabled applications, agentic workflows, API integrations,

Knowledge, Skills and Abilities

Required:

  • Intermediate to Advanced proficiency in Python and/or JavaScript/TypeScript, including modular design, testing, and packaging.
  • Intermediate proficiency with agent frameworks and agentic patterns: tool use, planning/execution loops, guardrails, evaluation, and prompt/version management.
  • Intermediate proficiency building and consuming REST APIs, and integrating enterprise systems with OAuth/JWT, secrets management, and secure data handling.
  • Intermediate proficiency with CI/CD, automated testing (unit/integration), linting, and observability for AI applications.
  • Intermediate understanding of security best practices, architecture design principles, and responsible AI/data governance.
  • Intermediate communication skills, written and verbal, and demonstrated ability to collaborate with cross-functional stakeholders and mentor junior engineers.
  • Intermediate experience with cloud AI platforms - preferably AWS Cloud, AWS Bedrock, and Databricks Mosaic AI - and vector stores or retrieval-augmented generation (RAG) patterns.
  • Intermediate knowledge of AI-native engineering using Claude Code, Codex, GitHub Copilot, or equivalent coding agents.

Preferred:

  • Experience delivering evaluation frameworks, red-teaming, or LLM observability tooling.

Travel Requirements

  • No travel is required for this position.
Our compensation reflects the cost of labor across several U.S. geographic markets, and we pay differently based on those defined markets. The base pay range for this position is $152,000 - $215,000 annually. The base pay range may take into account the candidate’s geographic region, which will adjust the pay depending on the specific work location. The base pay offered will take into account the candidate’s geographic region, job-related knowledge, skills, experience and internal equity, among other factors.In addition to the base salary, as part of our Total Rewards program, Exelixis offers comprehensive employee benefits package, including a 401k plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Employees are also eligible for a discretionary annual bonus program, or if field sales staff, a sales-based incentive plan. Exelixis also offers employees the opportunity to purchase company stock, and receive long-term incentives, 15 accrued vacation days in their first year, 17 paid holidays including a company-wide winter shutdown in December, and up to 10 sick days throughout the calendar year.

If you have a disability and need an accommodation in relation to the recruiting process, please email us at: [email protected].

WORKING CONDITIONS:

Our office is a modern space that fosters collaboration and creativity. Teams work closely together, sharing ideas and solutions in a supportive atmosphere. We provide all necessary equipment, including dual monitors and ergonomic chairs, to ensure a comfortable workspace.

DISCLAIMER:

The preceding job description has been designed to indicate the general nature and level of work performed by employees within this classification. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities and qualifications required of employees assigned to the job.

We are an Equal Opportunity Employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity, status as a veteran, and basis of disability or any other federal, state or local protected class.

Free account
Stop reading job ads. Get the ones that fit.
One free account turns this page into a shortlist built around your stack, your level and your pay.
Match on every job. Stack, seniority, pay and location, scored against your profile.
1,901,130 open roles. Read straight off company career pages, refreshed every day.
Unlimited applications. Every one you send is tracked in one place, on-site or on a company board.
3 tailored CVs a month. Rewritten for the exact job you are applying to. Included free.
Create a free account Continue with Google
Free forever. No card. Under a minute.

Your match

How well do you fit this role?
Two answers are enough for a real match. No account needed.
Check my fit
Answers stay in this browser until you create an account.

Recommended for you based on this role

AI/ML
Similar stack
Same company
Alameda
AI Systems Engineer 2 months ago
$153k – $191k per year • In office • TS/SCI • Full-Time • 5+ years exp • Bachelor's Degree • Chantilly
Python
AI/ML
LangChain
llama.cpp
Fine-tuning
NLP
LLM
RAG
Hallucination
Hugging Face
Machine Learning
DevOps
AWS
Apply
AI Engineer 2 months ago
≈ $113k – $220k per year (Estimated) • Hybrid • 3+ years exp • Bachelor's Degree • Jupiter
Python
JavaScript
TypeScript
SQL
C#
Node JS
Databases
MySQL
PostgreSQL
Redis
DynamoDB
AI/ML
Embeddings
Prompt Engineering
Function Calling
AI Agents
LLM
RAG
Amazon SageMaker
DevOps
Terraform
CloudFormation
CI/CD
AWS
Docker
Kubernetes
AWS Lambda
GitHub
Amazon S3
Amazon ECS
AWS Step Functions
Cybersecurity
HIPAA
Apply
$120k – $235k per year • In office • 6+ years exp • Bachelor's Degree • Washington • Mountain View
Python
C++
AI/ML
Copilot
Multimodal AI
Function Calling
Computer Vision
AI Agents
NLP
Transformers
LLM
Structured Outputs
Machine Learning
Apply
$120k – $235k per year • In office • 6+ years exp • Bachelor's Degree • Redmond
AI/ML
Voice Agents
Apply
$120k – $235k per year • In office • 4+ years exp • Bachelor's Degree • United States
Python
Go
JavaScript
Rust
C#
C++
AI/ML
InfiniBand
NVLink
DevOps
CI/CD
Platform Engineering
HPC
Apply
≈ $74k – $136k per year (Estimated) • In office • Full-Time • 4+ years exp • PhD • Rome
Python
JavaScript
TypeScript
Apex
Databases
Snowflake
Databricks
AI/ML
Cursor
LangChain
Claude
LlamaIndex
Prompt Engineering
AI Agents
Agentforce
LLM Guardrails
Multi-Agent Systems
DevOps
CI/CD
Apply
$167k – $278k per year • In office • 8+ years exp • Bachelor's Degree • Hoboken
Python
JavaScript
Java
TypeScript
Databases
Cassandra
RabbitMQ
ElasticSearch
Apache Kafka
AI/ML
Spark
AI Agents
LLM Guardrails
Agentic Workflows
Frontend
Angular
React.js
DevOps
CI/CD
Git
Cybersecurity
PCI DSS
SOC 2
Management
Agile
Apply
≈ $117k – $229k per year (Estimated) • In office • 8+ years exp • Bachelor's Degree • Nashville
Python
SQL
ABAP
ABAP
CDS Views
Databases
Snowflake
Apache Iceberg
SAP BW
AI/ML
Copilot
RAG
Semantic Search
Machine Learning
DevOps
AWS
Amazon S3
Analytics
Tableau
Power BI
ETL/ELT
AWS Glue
SAP BusinessObjects
Apply
≈ $68k – $146k per year (Estimated) • Hybrid • PhD • Montreal
Python
SQL
Python
FastAPI
AI/ML
LangChain
Scikit-learn
TensorFlow
PyTorch
LLM
RAG
LLMOps
DevOps
GCP
Azure DevOps
Azure
CI/CD
AWS
FinOps
Apply
≈ $70k – $134k per year (Estimated) • Hybrid • Full-Time • 7+ years exp • Bachelor's Degree • Toronto
AI/ML
Copilot
ChatGPT
Apply
$103k – $145k per year • In office • Full-Time • Bachelor's Degree • Alameda
Python
JavaScript
TypeScript
AI/ML
Prompt Engineering
AI Agents
Machine Learning
DevOps
Rest API
Git
GitHub
Apply
$129k – $182k per year • In office • Full-Time • 3+ years exp • Bachelor's Degree • Alameda
Python
JavaScript
TypeScript
Databases
Databricks
AI/ML
Copilot
Claude Code
Prompt Engineering
Function Calling
AI Agents
AWS Bedrock
LLM
OpenAI Codex
Context Engineering
LLM Guardrails
Agentic Workflows
DevOps
Rest API
CI/CD
Git
AWS
Apply
$103k – $145k per year • In office • Full-Time • Bachelor's Degree • Alameda
Python
JavaScript
TypeScript
AI/ML
Prompt Engineering
AI Agents
Machine Learning
DevOps
Rest API
Git
GitHub
Apply
$178k – $252k per year • In office • Full-Time • 11+ years exp • Master's Degree • Alameda
Apply
$160k – $227k per year • In office • Full-Time • 11+ years exp • PhD • Alameda
DevOps
GCP
Life Sciences
CDISC
Apply
$170k – $215k per year • In office • Full-Time • 2+ years exp • Bachelor's Degree • Alameda
Python
JavaScript
TypeScript
Databases
Databricks
AI/ML
Copilot
Claude Code
Model Context Protocol
Function Calling
AI Agents
AWS Bedrock
LLM
RAG
OpenAI Codex
LLM Evaluation
LLM Guardrails
Agentic Workflows
Multi-Agent Systems
DevOps
Rest API
CI/CD
AWS
Cybersecurity
Threat Modeling
Apply
IT Security Analyst 6 hours ago
$109k – $128k per year • In office • 4+ years exp • Bachelor's Degree • Alameda • Albuquerque
Cybersecurity
ISO 27001
NIST 800-171
Zero Trust
Least Privilege
Microsoft Entra ID
SIEM
Defense
CMMC
Apply
$109k – $128k per year • In office • 4+ years exp • Bachelor's Degree • Alameda
DevOps
Terraform
GCP
Chef
Azure
AWS
Configuration Management
Linux
Windows
TCP/IP
DNS
DHCP
Apply
$151k – $191k per year • In office • 6+ years exp • Bachelor's Degree • Alameda
SpaceTech
FMEA
Apply
Finance Manager 1 day ago
≈ $103k – $196k per year (Estimated) • Equity • In office • 7+ years exp • Alameda
Management
Oracle ERP
Apply
See all jobs
This is one of many
1,901,130 more open roles from verified company boards, updated every day.