Principal Full Stack Engineer, PV

At GSK we are building a best-in-class data and prediction powered team that is ambitious for patients.

GSK R&D and Digital and Tech's collective goal is to deliver business impact, including the acceleration of the discovery and development of medicines and vaccines to patients. The R&D Digital and Tech remit has expanded over the past 2 years, and to position GSK for the future, the change will strengthen R&D Tech, to provide more strategic impact, focus, accountability, and improved decision making in the use of Digital, Data and Analytics (DDA) to strengthen the pipeline.

Job Purpose

This role contributes to the design and delivery of web applications and platforms for PV Tech. You will work with architects, engineers, product owners, designers and other team members, and will actively participate in creating technical solutions, designs and implementations, and in the relentless improvement of PV Tech systems in alignment with agile and DevOps principles.

The Principal Full Stack Engineer demonstrates both depth and breadth across key engineering competencies, e.g. front-end and back-end software development, testing, DevOps and cloud. They can collaborate with experts from other subject domains. Primary responsibilities include building React-based applications and the services behind them, and deploying them as containers on Azure.

In addition, the role will demonstrate core engineering knowledge and experience of industry technologies, practices and frameworks such as React, micro-frontend architecture with module federation, containerization, cloud-based platforms, API design, and AI-assisted development. Examples of technologies include React, TypeScript/JavaScript, Webpack or Vite module federation, Node.js, Java/C#/Python, REST/GraphQL APIs, Docker, Azure App Service, Azure Container Registry, Git, GitHub, GitHub Copilot, Claude Code, Azure DevOps, Selenium/Playwright/Cypress, Jest/JUnit/NUnit, SAFe and Kanban.

The Principal Full Stack Engineer, PV Tech role is a senior technical role and will provide you the opportunity to lead key activities to progress your career.

These responsibilities include the following:

• Designing and implementing end-to-end safety data platforms with modern AI-Native solutions by leveraging technologies such as Generative AI, RAG, Vector Databases, Agentic AI, LLMOps,, Semantic Search etc

• Designing, building and maintaining React applications and the back-end services and APIs that support them.

• Designing and implementing micro-frontend architectures using module federation, including shared dependencies, versioning, and independent deployment of remote modules.

• Containerizing applications and deploying them to Azure App Service, including image builds, container registries, configuration, scaling and monitoring.

• Building and maintaining CI/CD pipelines (e.g. Azure DevOps, GitHub) for build, test, security scanning and deployment of containerized applications.

• Using AI coding assistants such as GitHub Copilot and Claude Code in daily development and helping teams adopt them effectively and responsibly.

• Defining and sharing best practices for AI-assisted development, such as prompting and context, code review of AI-generated code, testing expectations and security guardrails.

• Conducting PoCs of new technologies and helping to embed them in product teams.

• Ensures that technical delivery is fully compliant with GSK Security, Quality and Regulatory standards.

• Ensures use of relevant R&D Tech / central services and collaborating with service partners in identification and delivery of service improvements.

• Maintains best practices for engineering and architecture on our Confluence site. This requires hands-on experience with cutting-edge technology.

• Pro-actively engages in experimentation and innovation to drive relentless improvement.

Why you?

Basic Qualifications:

Are you ready to work in an environment where you are continuously expected to work on projects with new technology and expected to use this technology to deliver real business value?

We are looking for professionals with these required skills to achieve our goals:

• Bachelor’s degree in Computer Science Engineering or relevant technical discipline.

• Total 6+ years of experience, proficient with at least 3 of the below skills, and able to demonstrate knowledge and value with relevant experience in all the following competencies:

• Experience in building production React applications with TypeScript/JavaScript

• Experience in Cloud AI services, Generative AI, LLMs, RAG, Vector Databases LLMOps, Semantic Search, agentic AI, and multi-modal AI technologies

• Experience with module federation and micro-frontend architecture

• Experience with containerization (Docker) and deploying containerized applications to Azure App Service

• Experience using GitHub Copilot and Claude Code (or similar AI coding assistants) to build and ship software

• Back-end development and API design, using Node.js, Java, C#/.NET or Python

• Software development, architecture design & technology platforms/frameworks

• Agile, DevOps & Automation [of testing, build, deployment, CI/CD, etc.

• Testing strategies & frameworks, including unit, integration and end-to-end testing

Role requires:

• Experience in delivering high-quality engineered web applications

• Knowledge of industry standards and technology platforms aligned to GSK and R&D roadmaps

• Excellent communication, negotiation, influencing and stakeholder management skills

• Customer focus and excellent problem-solving skills

• Computer Science Engineering or related bachelor's degree software technologies.

• Familiarity and use of various open-source ecosystems including JavaScript, TypeScript, Node.js, Java, Python etc.

• Good understanding of various software paradigms: domain-driven, procedural, data-driven, object-oriented, functional.

• Familiar with .Net Core (C#), Java, Python.

• Demonstrable knowledge depth in more than one area of software engineering and technology.

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

• Experience in agile software development and DevOps, relevant technology platforms [e.g., Kubernetes] and frameworks [e.g. Docker], including cloud technologies on Azure and GCP

• Experience with web performance, accessibility and UI testing, and with component libraries and design systems.

• Experience with authentication and authorization (e.g. OAuth, OpenID Connect, Azure Entra ID) and secure coding practices.

• Experience with observability and monitoring of web applications (e.g. Azure Monitor, Application Insights).

• Subject matter expertise in clinical development.

• PV Tech requires Engineers with understanding of the relevant technical and scientific domains. Able to deliver continuous change to meet rapidly evolving R&D strategy and ambition.

• Experience with agile development methods, with security strategies and best practices, data integration mechanisms, architectural design tools, delivering and integrating COTS applications, areas of Service Oriented Architecture (SOA), Application Integration, Business Process Management and Data Quality.

• Experience in applying AI/ML, data curation, workflow, and advanced visualization techniques to enable decision support across multiple products and assets to drive results across R&D business operations.

At GSK we value diversity (Gender, LGBTQ +, PwD etc.) and treat all candidates equally. We aim to create an inclusive workplace where all employees feel engaged, supportive of one another, and know their work makes an important contribution.

Skills

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases - to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

Inclusion at GSK:

As an employer committed to Inclusion, we encourage you to reach out if you need any adjustments during the recruitment process.

Please contact our Recruitment Team at [email protected] to discuss your needs.

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