Manager, Business Systems
Confirmed on the employer's own hiring board on Sep 24, 2026. First seen by Alion on Sep 23, 2026.
Company Description
Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant® is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer. For more information, visit guardanthealth.com and follow the company on LinkedIn, X (Twitter) and Facebook.
Position Summary:
The Manager, Business Systems is a hands-on leadership role responsible for managing and optimizing Oracle ERP Cloud applications across Record to Report (R2R), Procure to Pay (P2P), Order to Cash (O2C), ARCS, RMCS, Billing, and Revenue Management processes.
This role combines functional and technical expertise with strong leadership skills to support daily ERP operations, system enhancements, Projects, integrations, and strategic initiatives. The Manager will lead ERP support resources and partner closely with Finance and Operations stakeholders to deliver scalable, reliable, and compliant business solutions.
The ideal candidate will possess strong analytical, problem-solving, and communication skills, with the ability to work cross-functionally and drive continuous improvement across enterprise systems and business processes.
Essential Duties and Responsibilities:
Lead analysis, design, implementation, and support of the Oracle Fusion Financial Cloud production environment for the Record to Report, Order to Cash, and Procure to Pay track (GL, AR, AP, FA, CM, SLA, PO, OM, Fusion Tax).
Define team structure, roles, and responsibilities to ensure effective coverage across ERP functional areas (R2R, P2P, O2C).
Manage resource planning, capacity, and workload distribution to meet business priorities and SLAs.
Coordinate with end-users and other stakeholders to ensure timely and accurate performance of the production environment supporting Finance and Operations, and support Month-End, Quarter-end, and Year-end Close.
Take ownership of setting up and configuring the Oracle Fusion Cloud application, and participate in testing during system upgrades, Projects, and enhancements.
Lead and manage a team of ERP analysts and support resources, including offshore teams, ensuring high-quality delivery and continuous development.
Own prioritization and governance of ERP enhancements, balancing business needs, risk, and system performance.
Act as the primary point of contact for Finance and Operations leadership for all ERP-related initiatives, escalations, and strategic discussions
Work closely with the integration team to design, troubleshoot, and resolve data-related issues in daily operations. Suggest & maintain monitoring reports.
Creates, analyzes, and executes complex reports, queries, and data using BI Publisher/OTBI to support the various reporting requirements of Finance and Operations.
Manage backlog of user requests, with regular status reporting of prioritization of new items, WIP, and completed items.
Stay current with vendor upgrades, new functionality, and feature releases, and assess adoption strategies.
Lead organizational change management efforts related to ERP enhancements, including communication, training, and user adoption strategies.
Understand Guardant Health’s business models and work closely with end-users to identify, recommend, and implement business process improvements.
Perform as a core team member and/or participate in ERP project initiatives.
Document systems procedures to facilitate cross-training.
Qualifications:
Bachelor's degree with 12+ years of experience with a concentration in Computer Science, Information Technology, information systems, or a related field (required)
Strong hands-on functional experience with Oracle Fusion Cloud Financials.
Hands-on experience supporting a live Oracle Fusion Cloud production environment, including troubleshooting functional issues, configurations, enhancements, and ongoing production support.
Experience gathering business requirements, designing solutions, configuring Oracle Fusion, leading testing/UAT, and supporting deployments
Strong Finance and Accounting process knowledge with the ability to work directly with Finance stakeholders and translate business requirements into Oracle solutions.
Experience leading ERP analysts/ support resources and working with offshore teams/vendors while remaining hands-on when needed.
Strong communication, stakeholder management, problem-solving, and interpersonal skills.
Preferred Experience:
Experience with RMCS, ARCS, Advanced Collections, Revenue Recognition/Billing, Fusion Tax, Procurement/PO, and Order Management/OM.
Experience with Oracle reporting tools such as OTBI, BI Publisher, FRS, and SmartView.
Experience with Oracle integrations and middleware platforms such as MuleSoft or similar technologies.
Oracle Fusion Cloud Financials certifications.
Experience with Oracle EPM, including EPBCS/FCCS and EDM.
SOX, audit, application security, and access-control experience
Healthcare or life sciences industry experience.
AI & Digital Fluency
- Demonstrate curiosity, sound judgment, and the ability to critically evaluate and responsibly leverage AI-enabled tools in accordance with company policies, ethical standards, and regulatory requirements to improve the efficiency, effectiveness, and quality of work.
Hybrid Work Model: This section is applicable to onsite employees who are eligible for hybrid work location as specified by management and related policies.Guardant has defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be requiredto be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients.
The annualized base salary ranges for the primary location and any additional locations are listed below. This range does not include benefits or, if applicable, bonus, commission, or equity. Each candidate’s compensation offer will be based on multiple factors including, but not limited to, geography, experience, education, job-related skills, job duties, and business need. Primary Location: Palo Alto, CA Primary Location Base Pay Range: $150,800 - $207,350 Other US Location(s) Base Pay Range: $128,180 - $176,248 If the role is performed in Colorado, the pay range for this job is: $135,720 - $186,615Employee may be required to lift routine office supplies and use office equipment. Majorityof the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Abilityto sit for extended periods of time.
Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities, long-term conditions, mental health conditions, or sincerely held religious beliefs. If you need support, please reach out to [email protected]
A background screening including criminal history is required for this role. GH will consider qualified applicants with criminal arrest or conviction histories in a manner consistent with applicable law including but not limited to the LA County Fair Chance Policies and the Fair Chance Act (Gov. Code Section 12952).
Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
All your information will be kept confidential according to EEO guidelines.
To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our Privacy Notice for Job Applicants.
Please visit our career page at: http://www.guardanthealth.com/jobs/