Staff Scientist

Job Family:

Travel Required:

Clearance Required:

We are currently searching for a Staff Scientist to provide senior-level bench expertise and scientific leadership, while remaining responsive to related laboratory needs and evolving programmatic priorities within the National Institutes of Health (NIH). This is a full-time, on-site opportunity in Bethesda, MD.

What You Will Do:

• Investigate genetic modifiers and biological mechanisms influencing disease severity and clinical outcomes.
• Apply cellular biology, molecular biology, immunology, and bioinformatics methods to study red blood cell dysfunction, acute pain, and inflammation.
• Identify and evaluate biomarkers for monitoring disease processes and treatment response.
• Conduct preclinical studies using animal models, primarily mice, to assess disease mechanisms and investigational therapies.
• Integrate genotype-phenotype analyses with clinical, laboratory, imaging, and diagnostic data to characterize disease manifestations and identify therapeutic targets.
• Evaluate drugs and experimental compounds in preclinical and clinical research to reduce hemoglobin polymerization, improve red blood cell flexibility and flow properties, or increase fetal hemoglobin production.

What You Will Need:

• PhD or MD, human genetics, molecular biology, biochemistry, immunology or closely related field.
• Minimum FIVE (5) years of post-doc research experience in areas such as translational research, genetics/ genomics, immunology, and/ or molecular biology.
• Multiple first-author publications in peer reviewed journals.
• Hands-on experience working with murine models, specifically transgenic mice.
• Experience in hematology, vascular biology, red blood cell health, and/or related fields such as nephrology.
• Proficiency in tissue culture, biochemistry and molecular biology assays, gene expression analysis, and/ or processing patient bio-samples.
• Experience with bioinformatics, statistical interpretation, and managing interdisciplinary research projects.
• Must be able to obtain and maintain a Federal or DoD “public trust”; candidates must receive approved adjudication prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred.

What Would Be Nice To Have:

• Strong written and verbal communication, organizational, and time management skills.
• Detail oriented.
• Able to work independently as well as collaboratively as a team member.
• Experience in training, teaching, and mentoring junior research staff, graduate students, and post-doctoral fellows is strongly preferred.
• Strong evidence of independent scientific leadership, publications, collaboration management and related skill sets.

What We Offer:

Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.

Benefits include:

• Medical, Rx, Dental & Vision Insurance

• Personal and Family Sick Time & Company Paid Holidays

• Parental Leave

• 401(k) Retirement Plan

• Group Term Life and Travel Assistance

• Voluntary Life and AD&D Insurance

• Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts

• Transit and Parking Commuter Benefits

• Short-Term & Long-Term Disability

• Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities

• Employee Referral Program

• Corporate Sponsored Events & Community Outreach

• Care.com annual membership

• Employee Assistance Program

• Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)

• Position may be eligible for a discretionary variable incentive bonus

About Guidehouse

Guidehouse is an Equal Opportunity Employer-Protected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation.

Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.

If you have visited our website for information about employment opportunities, or to apply for a position, and you require an accommodation, please contact Guidehouse Recruiting at 1-571-633-1711 or via email at [email protected]. All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation.

All communication regarding recruitment for a Guidehouse position will be sent from Guidehouse email domains including @guidehouse.com or [email protected]. Correspondence received by an applicant from any other domain should be considered unauthorized and will not be honored by Guidehouse. Note that Guidehouse will never charge a fee or require a money transfer at any stage of the recruitment process and does not collect fees from educational institutions for participation in a recruitment event. Never provide your banking information to a third party purporting to need that information to proceed in the hiring process.

If any person or organization demands money related to a job opportunity with Guidehouse, please report the matter to Guidehouse’s Ethics Hotline. If you want to check the validity of correspondence you have received, please contact [email protected]. Guidehouse is not responsible for losses incurred (monetary or otherwise) from an applicant’s dealings with unauthorized third parties.

Guidehouse does not accept unsolicited resumes through or from search firms or staffing agencies. All unsolicited resumes will be considered the property of Guidehouse and Guidehouse will not be obligated to pay a placement fee.