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Salary
$186k per year
Location
Remote (United States, PT hours)
Seniority
Senior
Employment
Full-Time

First seen by Alion on Oct 27, 2026.

Overview
Company
Impact
Profile match
At Horizon Therapeutics, we believe science and compassion must work together to transform lives. We are driven to deliver innovative medicines to those living with rare, autoimmune and severe inflammatory diseases because we uniquely understand the patient journey. For us, success is measured by the numbers that matter most - the number of lives we touch, the number we change and those we work to help save.
Backed by NEA, Atlas Venture

This a Full Remote job, the offer is available from: United States

Career Category

Business Development

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. Amgen is advancing a broad and deep pipeline and portfolio of medicines to treat heart disease, obesity and obesity-related conditions, rare diseases, inflammatory conditions and cancer. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Senior Program Manager

What you will do

Let’s do this. Let’s change the world. In this vital role you will be responsible for managing complex projects or programs. You will oversee all aspects of the project lifecycle, from planning and execution to monitoring and closing. This role often involves managing a project team and coordinating with multiple departments.

This is a key role whose overarching objective is to drive the development and execution of Medical Strategy in collaboration with Medical Affairs Leads. In this vital role, you will ensure key deliverables including medical plans, insights, budgets and goals are brought to completion. The Senior Manager is a cross-functional, collaborative role across global and local medical teams. You will identify metrics, progress, interdependencies, and concerns, facilitate resolution as needed, and keep the Medical Affairs Team aligned around its priorities.

The Sr. PM role will partner with the Asset Lead to drive cross-functional planning, manage project risks, and drive resolution of complex issues while aligning strategic goals across the broader organization.

Given close partnership with USML, GMAL, and global cross-functional stakeholders, the Senior Manager must maintain working hours with meaningful Pacific Time overlap. Availability generally from 8:00 a.m. to 5:00 p.m. Pacific Time, plus flexibility for key meetings, business priorities, and global deliverables, is required.

Responsibilities:

  • Drive the coordination and integration of insights in partnership with the Medical Affairs Lead to inform product strategy for global and local teams.
  • Be a key point of communication to ensure execution of the Medical Plan, including goal development and regular progress tracking.
  • Drive the Medical Plan process and ensure alignment between global and local Medical leads, including large and ROW/emerging markets.
  • Understand the Global Medical Strategy and ensure integration through close partnership with EGT, AUEG, IBT and other critical cross-functional partners.
  • Drive decision making within the Global Medical Affairs Team and ensure decisions, actions, and follow-up are clearly documented.
  • Identify key deliverables for each function and their interdependencies; maintain integrated plans
  • Implement standard methodologies and reinforce cross-functional alignment and accountability.
  • Identify project issues, risks, and resource gaps; facilitate resolution, contingency planning, and escalation as appropriate.
  • Reinforce sound decision making according to Amgen’s Decision-Making Framework.
  • Monitor and communicate progress, adherence to timelines, and variance from plan to Medical Affairs leadership.
  • Facilitate resource planning, financial planning, and capacity assessments in partnership with the Asset Lead.
  • Conduct risk management, contingency, and scenario planning using a variety of project management tools.
  • Support continuous improvement within the Medical Affairs Team and Program management function.
  • Drive operational excellence and automation by applying approved emerging technologies, including AI tools such as Copilot, to strengthen Medical planning, reporting, and ways of working.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The qualified professional we seek is a Senior Manager with strong program-management experience and the ability to work effectively in a complex, global matrix environment with these qualifications.

Basic Qualifications:

Doctorate degree and 2 years of Project Management experience

OR

Master’s degree and 4 years of Project Management experience

OR

Bachelor’s degree and 6 years of Project Management experience

OR

Associate’s degree and 10 years of Project Management experience

OR

High school diploma / GED and 12 years of Project Management experience

Preferred Qualifications:

  • 5+ years of project or program-management experience in pharmaceutical, biotechnology, healthcare, or another complex, regulated environment.
  • 8+ years of industry experience in biotechnology, pharmaceutical, or healthcare fields.
  • Experience supporting Global Medical Affairs, Medical Operations, Finance, Scientific Communications, or cross-functional product teams.
  • Experience in a role requiring broad communication across multiple groups, levels, and interest groups, with responsibility for influencing change and results.
  • Experience leading global, cross-functional initiatives and influencing stakeholders across functions, geographies, and leadership levels without direct authority.
  • Experience tracking risks to project completion, including prioritizing, managing resolution, and communicating.
  • Comfort working through ambiguity and helping create structure when priorities, ownership, or next steps are still evolving. This includes asking thoughtful questions, identifying options, proposing next steps, and helping the team move from discussion to action.
  • Experience with integrated planning, milestone tracking, resource planning, financial planning, capacity assessments, and executive-level communication.
  • Experience tracking projects in Excel, OneNote, SharePoint, or electronic dashboard and reporting tools.
  • Technical fluency with SharePoint, CoPilot, Teams, and dashboard/reporting tools.
  • Experience with and curiosity about AI and emerging technologies, with a demonstrated interest in advancing practical solutions to business challenges

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

  • A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans
  • Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer. We make all employment decisions without regard to race, color, religion, sex or any other characteristic protected by applicable law.

We provide reasonable accommodations to applicants and employees with disabilities, consistent with legal requirements. Please contact us to request accommodation.

.

Salary Range

137,340.45USD -185,813.55 USD
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