Postdoctoral Fellow-MSH

Roles & Responsibilities:

Postdoctoral Fellow

The newly established laboratory of Dr. Ali May in the Department of Cell, Developmental and Regenerative Biology and the Department of Otolaryngology is seeking to hire a creative and motivated postdoctoral fellow to advance our investigations in how epithelial organ patterning contributes to upper airway disease.

Our lab employs methods of single cell RNAseq, bulk RNA-seq, high resolution confocal microscopy, 3D image-rendering and in vivo model systems to fundamentally elucidate how epithelial patterning contributes to disease. We aim to define how multiple cell types organize and differentiate during development, maintain themselves during homeostasis and regenerate following injury.

With guidance and mentorship from Dr. May, the successful candidate will spearhead a project using single cell multiomics and computational approaches to elucidate epithelial cell dynamics in the human nose and sinus. The study will involve the use of animal models and in vitro systems to characterize genetic drivers of epithelial architecture and function.

The May lab is a member of the Black Family Stem Cell Institute at Mount Sinai and the recently established Institute for Airway Science at the Mount Sinai Health System and Icahn School of Medicine at Mount Sinai. The successful candidate will interact frequently with collaborators in the research program and be supported in experimental design, analysis and presentation of findings, grant applications and scientific manuscript reviewing and writing.

Preferred experience and interests:

• Sample processing for genomics
• Single-cell RNAseq
• Bulk RNAseq
• R programming
• Cell/Tissue culture methods
• High-resolution microscopy
• Mouse model systems
• Flow Cytometry
• Epithelial biology

Requirements:

• Ph.D., M.D. or M.D./Ph.D. degrees with strong experience in molecular/cellular biology or related field

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