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Salary
≈ $69k – $158k per year (Estimated)
Location
In office (Cambridge)
Seniority
Architect · 10+ years exp
Employment
Full-Time

Confirmed on the employer's own hiring board on Oct 29, 2026. First seen by Alion on Sep 23, 2026.

Overview
Company
Impact
Profile match
One Nucleus is a membership organisation for the life sciences and healthcare sector, connecting companies, innovators and advisers in Cambridge, London and beyond. Founded in 2005, it runs networking events, training and purchasing schemes for its members. The organisation is headquartered on the Babraham Research Campus in Cambridge, United Kingdom.

Associate Director (Biology)

TRIMTECH Therapeutics, a well-funded and vibrant early-stage biotech based at Babraham Research Campus, Cambridge, UK, is expanding its team. We are seeking a highly skilled, experienced and enthusiastic Associate Director (Biology) to work closely with academic and CRO partners, internal chemists, and R&D leadership to create transformative new therapeutics.

Join our core team of experienced scientists and drug hunters to develop the next generation of protein degraders, based on the pioneering work of Dr. Leo James and Professor William McEwan (Science, 2024 and Cell, 2024). Our mission is to create novel small molecule degraders of protein aggregates to combat neurodegenerative diseases and address some of society's biggest challenges.

We are seeking an Associate Director to project lead strategically important internal or potential future collaborative programs. You will act as the primary scientific point of contact for external collaborators, managing stakeholders, keeping activities on time and within budget, and drive the project forward, working closely with R&D leaders, internal and external project teams.

If you are a passionate, experienced scientist with a track record of leading external partnerships and looking to make a significant impact in the field of drug discovery, we encourage you to apply to join our dynamic team at TRIMTECH Therapeutics. You will be a key contributor to the development of ground breaking treatments for neurodegenerative diseases.

What you will be doing:

  • Act as scientific lead for internal or external collaborative programmes, delivering milestones on time and on budget, working alongside senior R&D leadership.
  • Direct day-to-day activities of the project team and contract research organisations, providing scientific guidance, expertise, and clear direction, owning the day-to-day management of the project.
  • Clearly communicate issues, de-risking strategy, and progress to enable clear go- or no-go decisions on the project or specific activities.
  • Ensure all activities, protocols, risk assessments, records, and data (both internal and generated at external partners’ sites) are clearly recorded, kept up to date, and compliant with regulatory and H&S requirements
  • Create and present plans and results across a range of verbal and written channels to R&D, senior leadership, programme teams, and external stakeholders
  • Maintain strong awareness of internal and external developments in the field, proactively suggesting and evaluating new techniques and technologies to further collaboration goals.

Qualifications, Knowledge and Experience

  • Degree or PhD in a relevant field, with 10 years of relevant experience.
  • Significant experience and a proven track record of supporting or leading small molecule drug discovery and development programmes from target validation phases to delivering an advanced lead or candidate.
  • Experience working with external collaborators in a biotech setting to successfully deliver collaborative project milestones on time and on budget.
  • Experience of preparing and presenting project updates and plans to both internal and external stakeholders including project and governance meetings.
  • Demonstrated experience managing and leading external teams, ensuring CROs and/or academic partners adhere to timelines and making clear go/no-go decisions on activities, in a fast-moving environment
  • Working knowledge, expertise and problem-solving skills in targeted protein degradation (TPD), or molecular glue degraders
  • Exceptionally strong organisational skills, with the ability to prioritise work across internal teams and external partners.
  • A "can-do" problem-solving approach and passion for science, working respectfully and collaboratively and within a cross-functional team of outstanding scientists.

Desirable Skills and Attributes

  • Expertise with iPSCs and/or neuronal models for drug discovery.
  • Expertise with protein aggregates and their role in disease.
  • Line management experience

What We Offer

  • 28 days holiday + statutory and bank holidays
  • Life Insurance
  • Private Medical Insurance
  • Enhanced pension contribution
  • Discretionary bonus

We are committed to creating a diverse and inclusive workplace where everyone is treated with respect and has the opportunity to thrive. We welcome applications from people of all backgrounds, experiences and perspectives, and believe that different ideas and ways of thinking make us stronger.

Please send a CV and cover letter with your application.

Closing date for applications: 6th October 2026

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