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Salary
$84k – $105k per year
Location
Hybrid (Fremont, United States)
Seniority
Middle · 3+ years exp
Visa
H-1B filings in 12 months: 6 · green card filings: 1
Employment
Full-Time

Confirmed on the employer's own hiring board on Nov 13, 2026. First seen by Alion on Nov 12, 2026.

Overview
Company
Impact
Profile match
Our advanced ctDNA technologies enable the most sensitive detection with cancer insights from molecular residual disease to therapy selection.

At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient. Our highly sensitive assays combine tumor-and-normal profiling with proprietary algorithms to deliver advanced insights even as cancer evolves over time. Our products are designed to detect minimal residual disease (MRD) and recurrence at the earliest timepoints, enable selection of targeted therapies based on ultra-comprehensive genomic profiling, and enhance biomarker strategy for drug development.

Days Onsite: Monday, Tuesday, & 1 other day (Hybrid) -  Training will be onsite for 5 days / week

Summary:

The Research Associate 2, Operations Sustaining will provide operational and technical support for clinical lab products with focus on NeXT Personal Dx, Personalis’ ultrasensitive molecular residual disease assay. The role involves partnering with a cross-functional team to triage and resolve order and sample related issues and support process improvement and scalability opportunities.  

Responsibilities:

  • Participate in clinical laboratory sustaining support activities, including but not limited to tracking clinical sample and pipeline issues, troubleshooting, and documenting root cause and resolution.

  • Follow written procedure to update sample status and workflow to unblock stalled samples or address special sample movement requests.  

  • Collaborate with lab operations, client experience, clinical software, data management, pipeline, and quality teams to address sample processing or pipeline failures and customer requests. 

  • Partner with cross-functional teams to implement workflow improvements to support product growth. 

  • Additional responsibilities may include remote weekend lab sustaining support.

Education & Experience:

  • A Bachelor's degree in a molecular biology or related field with a minimum of 3 years of relevant experience; or a master's degree and 1 or more years of relevant experience.

  • Working knowledge in Next Generation Sequencing technology, LIMS, and SFDC. Experience with molecular residual disease assay is a plus.

  • Familiarity with operations of high throughput clinical laboratory including sample accessioning, sample processing, pipeline analysis, and report release. 

  • Highly organized and systematic, with superb attention to detail and the ability to prioritize and complete tasks with a high degree of accuracy.

  • Demonstrated quick learner and skilled in analytical thinking, utilizing data to drive decisions. 

The hiring range for this position is $84,000 to $105,000 per year, which may factor in various geographic regions. The base pay actually offered will take into account internal equity and also may vary depending on the candidate’s geographic region, job-related knowledge, skills, and experience among other factors. Our full-time regular positions also include an annual performance-based bonus (or a sales incentive plan) and long-term incentive units (equity) provided as part of our compensation package, in addition to a full range of medical, financial, and/or other benefits, dependent on the level and position offered.

Personalis is an equal opportunity employer and is committed to the full inclusion of all individuals. As part of this commitment, Personalis will ensure that persons with disabilities are provided with reasonable accommodations. If you need an accommodation to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please let your recruiter know, if/when they contacts you.

Protecting Our Candidates: At Personalis, we value your security. Please note that all official correspondence from our team will come exclusively from @personalis.com email addresses. We will never ask for personal financial information or conduct interviews over text or chat platforms. If you receive a suspicious request, it is likely a scam. We are committed to a safe recruitment experience and actively work with authorities to investigate and prosecute cyber crimes targeting our community.

Personalis is an Equal Opportunity Employer/Minorities/Females/Veterans/Disabilities. Personalis offers a competitive compensation package and benefits including medical, dental, vision, 401(k) match, ESPP, tuition reimbursement, sick/vacation time, commuter benefits/ EV charging stations, onsite gym, and wellness benefits. (For US only, benefits in other countries may vary.) 

#LI-Hybrid #LI-KK1

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