Research Scientist: RNAi Formulations
Confirmed on the employer's own hiring board on Nov 2, 2026. First seen by Alion on Oct 6, 2026.
Research Scientist: RNAi Formulations - Contract - Lexington, MA
Looking to be the heartbeat of medical research? Join our client as a Research Scientist and assist in turning innovative science into life-changing care!
Proclinical is seeking an Associate Research Scientist for RNAi Formulations to be focused on hands-on RNAi formulation development.
Primary Responsibilities:
This position will also focus on biophysical and analytical characterization as well as support the oligonucleotide delivery activities for injectable therapeutics.
Skills &Requirements:
- MS with approximately 3 years of relevant experience, or PhD with 1-3 years of relevant experience in pharmaceutical sciences, formulation sciences, chemical engineering, biophysics, analytical chemistry, oligonucleotide delivery, or a related discipline.
- Hands-on experience with oligonucleotide or antibodies/proteins formulation and characterization is strongly preferred.
- Experience developing or running analytical methods for solubility, viscosity, osmolality, aggregation, , stability, or other developability assessments for complex oligonucleotide or antibody/protein formulations.
- Familiarity with automation, high-throughput screening, and DoE-based formulation optimization is an advantage.
- Strong experimental planning, documentation, data analysis, and problem-solving skills.
- Excellent verbal and written communication skills, with the ability to work effectively across disciplines and functions.
- Awareness of external trends and advances in RNA delivery, oligonucleotide therapeutics, and clinical translation is a plus.
- A track record of scientific contributions, publications, or conference presentations in relevant areas is a plus.
The Research Scientist's responsibilities will be:
- Support the development and characterization of preclinical RNAi and oligonucleotide formulations across portfolio and platform projects.
- Execute hands-on formulation preparation, biophysical characterization, analytical testing, and data analysis to support formulation selection and developability assessments.
- Establish and run screening assays for oligonucleotides in early discovery, including formulation performance, solubility, viscosity, osmolality, degradation, , and stability assessments.
- Contribute to high-throughput and design-of-experiments approaches for formulation optimization, where applicable.
- Support long-term storage and stability evaluations for RNAi conjugates and oligonucleotide formulations.
- Maintain accurate experimental documentation and communicate findings through written summaries, reports, and internal presentations.
- Collaborate with internal stakeholders and external partners to support project deliverables and timelines.
- Identify technical gaps, propose practical solutions, and contribute to continuous improvement of formulation and characterization workflows.
- Thrive in a multidisciplinary, fast-paced research environment with competing priorities and tight deadlines.
Compensation:
- $35 to $39 per hour.
If you are having difficulty in applying or if you have any questions, please contact Shannon Briggs at[email protected]
If you are interested in applying to this exciting opportunity, then please click 'Apply' or to speak to one of our specialists please request a call back at the top of this page.
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