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First seen by Alion on Aug 26, 2026. Roche scores A on the Alion truth index.

Overview
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Roche is a Swiss healthcare group founded in Basel in 1896 and is unusual in operating two large divisions of comparable importance: prescription medicines and in vitro diagnostics. The pharmaceutical business is built on oncology, neurology, immunology, ophthalmology and haemophilia, with products such as Ocrevus, Hemlibra, Perjeta and Vabysmo, while the diagnostics division supplies laboratory analysers, molecular tests and sequencing systems to hospitals worldwide. The group owns the American biotechnology company Genentech outright and the Japanese firm Chugai in majority, is controlled by a family shareholder pool, and spends among the largest research budgets in the industry.

Responsibilities:

  • Agentic Architecture: Design, deploy, and scale multi-agent orchestration systems and autonomous workflows using cutting-edge frameworks.
  • Advanced RAG Pipelines: Build and optimize advanced retrieval-augmented generation (RAG) pipelines over massive, heterogeneous datasets (structured and unstructured).
  • State and Memory Management: Implement robust state management, short/long-term memory systems, and self-correction/reflection loops within agent networks.
  • Evaluation and Guardrails: Create and implement robust evaluation metrics, observability pipelines, and guardrails for content quality, hallucination reduction, bias mitigation, and safety standards.
  • Performance Optimization: Monitor and optimize AI inference cost, latency, throughput, token usage, and overall system reliability.
  • Security and Access Control: Implement robust access controls, data encryption, user authentication, and prompt injection mitigation across all LLM workflows.
  • Collaboration and Best Practices: Document and share reusable agent patterns, prompt libraries, and engineering components across cross-functional technical teams.

Requirements:

  • Demonstrated experience taking ownership of ambiguous tasks, successfully driving small to medium initiatives, and acting as a technical mentor.
  • Proven track record of engaging in knowledge-sharing initiatives, speaking at internal technical events, and navigating group dynamics in diversified settings.

Technical Skills:

  • GenAI Development: Advanced prompt engineering, fine-tuning, RAG/GraphRAG, schema-constrained outputs, function/tool-calling, and semantic caching.
  • Agentic Frameworks: LangChain, LangGraph, LlamaIndex, CrewAI, AutoGen, and DSPy.
  • Vector Databases: FAISS, Milvus, Qdrant, Pinecone, Weaviate, and Pgvector.
  • LLM Serving and Infra: vLLM, Hugging Face TGI, and Ollama (for local development).
  • Guardrails and Validation: NeMo Guardrails, Guardrails AI, Pydantic, and Instructor.
  • LLM Ops and Observability: Ragas, DeepEval, Langfuse, LangSmith, and Phoenix.
  • Data Parsing: Unstructured, Apache Tika, LlamaParse, and PDFPlumber.
  • Programming and DevOps: Python (FastAPI, asyncio), REST/GraphQL APIs, Git, CI/CD pipelines, Docker, Kubernetes, and OpenTelemetry.
  • Emerging Protocols: Model Context Protocol (MCP) and Agent2Agent communication standards.

AWS Ecosystem (Baseline Experience):

  • Amazon Bedrock: Foundation model access, custom configurations, and managed agent workflows.
  • Amazon SageMaker: Fine-tuning, hosting, evaluating, and deploying open-source LLMs.
  • Amazon OpenSearch Service: Vector search, hybrid search, and enterprise retrieval infrastructure.
  • AWS Step Functions: Multi-step orchestration and state machine management for hybrid AI/traditional pipelines.

Additional Qualifications:

  • Problem-Solving: An analytical mindset capable of breaking down highly abstract, ambiguous logic loops into predictable agent behaviors.
  • Collaboration: Ability to thrive in a fast-paced, product-focused agile engineering environment alongside data scientists and product owners.
  • Communication: Strong technical writing and communication skills for documenting complex system architectures and cross-functional collaboration.

Bonus: Domain and Regulatory Knowledge:

  • Experience or strong familiarity with the following clinical trial standards will give you a significant advantage:
  • Clinical Document Automation: Automating the full clinical document generation workflow, specifically translating protocols to Clinical Study Reports (Protocol CSR).
  • Data Lineage Workflows: Experience transforming raw clinical data and statistical outputs into structured regulatory documents (SDTM/ADaM/ARD TLG CSR).
  • CDISC Standards: Deep understanding of CDASH (CRFs), SDTM, ADaM, ARD/ARM, and Define-XML.
  • Regulatory Submissions: Familiarity with ICH M11 (protocol/SoA), ICH E3 (CSR), and eCTD Module 5
  • Compliance Frameworks: Designing software to align strictly with GxP, 21 CFR Part 11 and ICH guidelines, ensuring total auditability, traceability, and explainability.
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