MES Application & Integration Expert
Confirmed on the employer's own hiring board on Nov 7, 2026. First seen by Alion on Nov 6, 2026. Roche scores A on the Alion truth index.
At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.
The Position
Doing now what patients need next. A pioneer in the development of blood glucose monitoring and insulin delivery systems, Roche is committed to helping people with diabetes everywhere in the world through a broad portfolio of solutions for both people with diabetes and their professionals.
Combining the strengths of our portfolio of Diabetes Care as well as Point of Care products, the organization 'Near Patient Care Operations Mannheim/Indianapolis' aims to achieve best-in-class manufacturing and operational excellence, delivering the highest quality solutions for patients and Health Care Professionals.
We are seeking a proactive and skilled MES Engineer with 4+ years of experience to support, configure, and integrate Manufacturing Execution Systems within our production facility. In this role, you will bridge the gap between IT, OT (Operational Technology), and shop-floor operations, ensuring high system uptime, data integrity, and continuous process improvement.
The Opportunity
- In collaboration with IT and business partners, monitor and improve stakeholder and user experience to maximize utilization of OT applications and systems. Analyse and interpret data to provide recommendations for process improvements.
- Develop complex scripting solutions for advanced functionality
- Configure redundancy, failover strategies, and disaster recovery architectures
- Capable of gathering user requirements process steps and translating them to system requirements.
- You will assist in delivering internally and externally built systems.
- Lead system integration efforts between MES (preferably Siemens Opcenter), PLC, and enterprise systems
- Perform system sizing, network design support, and platform specifications
- Lead Computer System Validation (CSV) activities and provide on-site commissioning support
- Provides technical support for OT applications to end users and key business users. (On-call-support, including regular intervals outside of regular working hours).
- Troubleshoot complex issues related to communication, performance, and system stability
- Interface with stakeholders to gather requirements and present technical solutions
- Work independently to learn and investigate solutions; while also capable of collaborating and learning from other team members.
- Work in local and global projects in the area of OT applications.
- Exchange technical information with employees at other locations and form a network.
Who You Are:
- You gained your Bachelor degree in Computer Science, Informatics, Engineering, or equivalent.
- You have 4+ years of related experience.
- Knowledge of IT/OT solutions, networking, firewalls, databases, PLC (Program logic controller) and PLC integration with Manufacturing information systems.
- Familiarity with MES (Manufacturing Execution System) , SCADA and Rockwell products like FactoryTalk (AssetCenter, Metrics and Data Historian), Data transfer protocol like OPC UA.
- Knowledge of IT/OT solutions, operating systems, databases, laboratory information systems, manufacturing execution systems (MES), computer programming, and/or ISA95
- Familiarity with industrial communication protocols or scripting languages (e.g., Python, C#, Java, depending on your stack).
- Proficiency in SQL, relational databases, and querying shop-floor data.
- You influence with knowledge of manufacturing process design, preferably with special purpose processes. You are familiar with SDLC, GMP, and incident management.
- You use a detailed and analytically minded approach to problem solving.
- You can explain technical requirements and solutions to a broad range of stakeholders
- You carry out assigned tasks independently, autonomously and conscientiously with a high degree of customer/service orientation
The expected salary range for this position based on the primary location of Indiana is $85,000 - $157,800 Annual. Actual pay will be determined based on experience, qualifications and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance, as well as participation in a long-term incentive program. This position also qualifies for the benefits detailed at the link provided below.
Who we are
A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.
Let’s build a healthier future, together.
Roche is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.