1,894,174open jobs
110,870companies
254,113added this week
Browse all
Salary
$80k – $130k per year
Location
In office (Portland)
Seniority
Senior
Visa
H-1B filings in 12 months: 18 · for this role: 2

Confirmed on the employer's own hiring board on Oct 21, 2026. First seen by Alion on Oct 19, 2026. Schrodinger scores B on the Alion truth index.

Overview
Company
Impact
Profile match
Schrodinger is a scientific software company founded in 1990 that develops physics-based simulation combined with machine learning for molecular design. Its platform predicts binding affinity and material properties accurately enough to prioritise which compounds to synthesise, and it is used across the pharmaceutical industry. The company also runs its own drug discovery pipeline and collaborations.

We’re seeking a Senior Enterprise Applications Engineer to join us in our mission to transform the discovery of therapeutics and materials!

As a leader on the IT and Operations team, you’ll serve as a subject-matter expert and technical authority for NetSuite and related business applications. Partnering closely with teams across the company to understand business needs, design scalable solutions, improve data integrity, and deliver reliable systems and integrations, you’ll lead complex projects, troubleshoot critical production issues, influence technical direction, and mentor other team members.

Who will love this job:

  • An experienced software engineer who can make sound technical decisions, lead high-impact work, communicate risks early, and deliver solutions that support both immediate business needs and long-term system health
  • An excellent communicator and collaborator who enjoys building consensus across business teams.
  • A proactive, detail-oriented problem-solver who loves continuously improving
  • An independent manager with a track record of successfully leading complex projects or initiatives from planning through delivery

What you’ll do:

  • Lead complex business application projects, from requirements and design through implementation and support.
  • Own NetSuite configuration, customization, integrations, and ongoing system health, including work with Coupa and other applications.
  • Partner with business teams to improve workflows and deliver scalable solutions.
  • Troubleshoot production issues and lead data-quality improvements.
  • Set technical standards for testing, documentation, deployments, and operational support.
  • Communicate plans, risks, and decisions; support and train users.

What you should have:

  • Bachelor’s degree or equivalent in Computer Science, Information Systems, or a related field
  • Significant experience administering, customizing, and supporting NetSuite, including SuiteScript 1.0 and 2.x.
  • Experience developing and integrating enterprise applications across a polyglot environment, including JavaScript/TypeScript, .NET/C#, PHP, SQL, and web services.
  • Experience with cloud platforms such as GCP and AWS, plus Git and related development tools.
  • A track record of leading application projects and resolving complex production issues.
  • Experience with Coupa or similar business applications; Salesforce experience is a plus.
  • Strong communication skills and the ability to work effectively with technical and business teams.

Pay   and perks:

Schrödinger understands it’s people that make a company great. Because of this, we’re prepared to offer a competitive salary, equity-based compensation, and a wide range of benefits that include healthcare (with dental and vision), a 401k, pre-tax commuter benefits, a flexible work schedule, and a parental leave program. We have catered meals in the office, a company culture that is relaxed but engaged, and over a month of paid vacation time.  Our Administrative and Human Resources departments also plan a myriad of fun company-wide events. New York is home to our largest office, but we have teams all over the world. Schrödinger is honored to have been included in Crain's New York Best Places to Work, BuiltIn's NYC Best Place to Work, and Newsweek's list of America's 100 Most Loved Workplaces. 

Estimated base salary range: $80,000 - $130,000. Actual compensation package is dependent on a number of factors, including, for example, experience, education, degrees held, market data, and business needs. If you have any questions regarding the compensation for this role, do not hesitate to reach out to a member of our Strategic Growth team. 

Sound exciting? Apply today and join us!

As an equal opportunity employer, Schrödinger hires outstanding individuals into every position in the company. People who work with us have a high degree of engagement, a commitment to working effectively in teams, and a passion for the company's mission. We place the highest value on creating a safe environment where our employees can grow and contribute, and refuse to discriminate on the basis of race, color, religious belief, sex, age, disability, national origin, alienage or citizenship status, marital status, partnership status, caregiver status, sexual and reproductive health decisions, gender identity or expression, sexual orientation, or any other protected characteristic. To us, "diversity" isn't just a buzzword, but an important element of our core principles and key business practices. We believe that diverse companies innovate better and think more creatively than homogenous ones because they take into account a wide range of viewpoints. For us, greater diversity doesn't mean better headlines or public images - it means increased adaptability and profitability.

Free account
Stop reading job ads. Get the ones that fit.
One free account turns this page into a shortlist built around your stack, your level and your pay.
Match on every job. Stack, seniority, pay and location, scored against your profile.
1,894,174 open roles. Read straight off company career pages, refreshed every day.
Unlimited applications. Every one you send is tracked in one place, on-site or on a company board.
3 tailored CVs a month. Rewritten for the exact job you are applying to. Included free.
Create a free account Continue with Google
Free forever. No card. Under a minute.

Your match

How well do you fit this role?
Two answers are enough for a real match. No account needed.
Check my fit
Answers stay in this browser until you create an account.

Recommended for you based on this role

Backend
Similar stack
Same company
Portland
$160k – $210k per year • In office • 5+ years exp • Bachelor's Degree • New York
Python
JavaScript
SQL
DevOps
Rest API
Linux
SOAP
Management
Oracle ERP
Apply
$180k – $275k per year • In office • Full-Time • 8+ years exp • Bachelor's Degree • South San Francisco
AI/ML
Cursor
Claude Code
LLM
Federated Learning
Machine Learning
Apply
Software Developer 1 day ago
$99k – $136k per year • Hybrid • Full-Time • 3+ years exp • Bachelor's Degree • United States
Python
Java
Kotlin
TypeScript
PowerShell
C#
C#
.NET
AI/ML
Copilot
Claude
ChatGPT
Prompt Engineering
AI Agents
RAG
DevOps
CI/CD
Linux
Windows
Cybersecurity
GDPR
MedTech
IEC 62304
Verification & Validation
Apply
$178k – $185k per year • Equity • In office • 5+ years exp • Bachelor's Degree • United States
Java
SQL
Java
Spring Framework
Spring Boot
Databases
PostgreSQL
Cassandra
Apache Kafka
DevOps
Rest API
Helm
Azure
CI/CD
Docker
Kubernetes
Apply
Developer II (Hybrid) 2 months ago
$75k – $105k per year • Hybrid • Full-Time • 2+ years exp • Bachelor's Degree • New Hartford
Apply
In office • Full-Time
Python
JavaScript
TypeScript
SQL
C#
Node JS
C#
.NET
AI/ML
Copilot
Frontend
React.js
DevOps
Rest API
Azure DevOps
Azure
Git
GitHub
Cybersecurity
Microsoft Entra ID
Management
SharePoint
Apply
≈ $63k – $133k per year (Estimated) • Equity • In office • Full-Time • 12+ years exp • Bachelor's Degree • Quebec • Montreal
JavaScript
C#
C#
.NET
Frontend
Next.js
React.js
DevOps
Azure
Kubernetes
Cybersecurity
ISO 27001
Management
Agile
Apply
≈ $20k – $41k per year (Estimated) • Hybrid • Full-Time • 4+ years exp • Bengaluru • Mumbai
Java
SQL
PowerShell
C#
Bash
Java
Spring Boot
C#
.NET
Databases
MS SQL
DevOps
Terraform
Helm
Azure DevOps
GitHub Actions
Terragrunt
Dynatrace
Azure
CI/CD
AWS
Docker
Kubernetes
Platform Engineering
Azure AKS
GitHub
Linux
Windows
Unix
DNS
Cybersecurity
Microsoft Entra ID
Analytics
Azure Data Factory
Apply
≈ $93k – $203k per year (Estimated) • Remote (United Kingdom) • Full-Time
Java
SQL
C#
C++
C#
ASP.NET Core
Databases
PostgreSQL
MS SQL
DevOps
Azure
Windows Server
Kubernetes
Azure AKS
Apply
In office • Full-Time
SQL
AI/ML
Copilot
Embeddings
RAG
Copilot Studio
DevOps
Rest API
Cybersecurity
Microsoft Entra ID
Management
Power Automate
Power Apps
Apply
$155k – $270k per year • In office • 5+ years exp • New York
Python
Ruby
Bash
DevOps
Terraform
Helm
GitHub Actions
CI/CD
Docker
Kubernetes
Linux
Apply
In office • 2+ years exp • Hyderabad
Python
JavaScript
C++
Frontend
React.js
Apply
≈ $17k – $51k per year (Estimated) • In office • 4+ years exp • Bachelor's Degree • Hyderabad
Java
Java
Spring Boot
Databases
PostgreSQL
Apache Kafka
AI/ML
Machine Learning
DevOps
Kubernetes
Management
Agile
Apply
In office • 1+ year exp • Hyderabad
Python
JavaScript
Node JS
Bash
Frontend
React.js
DevOps
Terraform
GCP
Helm
GitHub Actions
OpenTofu
Azure
CI/CD
GitOps
Git
AWS
Docker
Kubernetes
GitHub
Apply
≈ $19k – $42k per year (Estimated) • In office • PhD • Hyderabad
Python
Apply
$85k – $125k per year • In office • Full-Time • 6+ years exp • High School Diploma • Tacoma • Seattle • Irvine • Denver • Bellevue
Management
SharePoint
Apply
≈ $36k – $66k per year (Estimated) • In office • Full-Time • 4+ years exp • Bachelor's Degree • Portland
Apply
≈ $37k – $82k per year (Estimated) • In office • High School Diploma • Portland
Apply
$46k – $52k per year • Remote (United States) • Internship • Portland
Python
SQL
Analytics
Microsoft Excel
Apply
$101k – $133k per year • In office • 3+ years exp • Bachelor's Degree • Portland
Apply
See all jobs
This is one of many
1,894,174 more open roles from verified company boards, updated every day.