Scientist- CBA

Scientist,CBA

The Jackson Laboratory | Bar Harbor ME

About the Role

The Jackson Laboratory is seekinga highly motivated Scientist to join our Core Scientific Services team within the Metabolic Phenotyping Core. This position provides scientific expertise, technical leadership, and operational support for advanced in vivometabolic phenotyping technologies and services that enable cutting-edgebiomedical research across diverse scientific programs, including obesity, diabetes, MASH,atherosclerosisand muscle biology.The Scientist will partner with investigators, research staff, and cross-functional teams to develop, optimize, and implement scientific solutions that support internal and external research initiatives. This individual will leveragetechnical expertiseto evaluate emerging technologies, troubleshoot complex scientific challenges, ensure quality standards, and deliver exceptional scientific serviceto a broad research community.

The ideal candidate is an independent scientist with strong technical proficiency, a collaborative mindset, and a passion for enabling scientific discovery through shared resources and innovative technologies.

Key Responsibilities

• Design, develop, optimize, and execute in vivometabolic phenotyping workflows, assays, and methodologies that support core service operations and research objectives.

• Analyze, interpret, and communicate experimental data and results to diverse scientific audiences.

• Evaluate, implement, and validatenew technologies, equipment, and workflows to enhance service capabilities and operational efficiency.

• Develop and maintainstandard operating procedures (SOPs), quality control processes, and best practices to ensure data integrity and reproducibility.

• Troubleshoot complex technical and scientific issues and identifyinnovative solutions to improve performance and outcomes.

• Collaborate with multidisciplinary teams to support research initiatives, grant applications, publications, and strategic projects.

• Train, mentor, and providetechnical guidance to research staff, students, and laboratory personnel.

• Contribute to the strategic growth and continuous improvement of core scientific services through process optimization and adoption of emerging technologies.

• Maintain compliance with institutional, regulatory, and safety requirements.

Knowledge, Skills, and Abilities

• Demonstrated expertisein one or more of the following areas: obesity, metabolic disease (including type-2 diabetes, MASH, atherosclerosis), aging, skeletal muscle biology, or islet (β-cell) biology.

• Expertisein preclinical pharmacology, including in vivoefficacy, execution, analysis, and interpretation.

• Proficiency with indirect calorimetry / metabolic cage systems (e.g., Sable Systems Promethion, or equivalent), Body compositionanalysis using EchoMRI, DEXA, and/or microCT, core metabolic phenotyping assays, including glucose tolerance tests (GTT), insulin tolerance tests (ITT), and mixed-meal tolerance tests (MMTT), treadmill-based endurance capacity testing.

• Hyperinsulinemic-euglycemic and hyperglycemicclamp techniques.

• Muscle biology experience is a strong plus.

Desirable:

• Surgical proficiencyin transplantation techniques, including grafting under the kidney capsule

Minimum Qualifications

• Master’s degree in biology, Biomedical Sciences, Genetics, Molecular Biology, Biotechnology, Bioinformatics, or a related scientific discipline required; Ph.D. preferred.

• Four (4) or more years of relevant scientific experience supporting research programs, scientific services, core facilities, biotechnology, pharmaceutical, academic, or contract research environments.

• Experience with advanced laboratory technologies, instrumentation, and scientific data analysis.

• Track recordof scientific achievement demonstratedthrough research contributions, publications, presentations, technology implementation, or project leadership preferred.

Why Join Us

As part of Core Scientific Services, you will play a vital role in advancing research across multiple scientific disciplines while working with state-of-the-arttechnologies and a collaborative community of scientists. This position offers the opportunity to influence research outcomes, drive innovation, and help enable discoveries that improve human health.

Pay Range: $85987 - $143962 per year, dependent upon experience.

About JAX:

The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California), Japan and China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.

Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community. For more information, please visitwww.jax.org.

EEO Statement:

The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.