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Salary
$184k – $215k per year
Location
Hybrid (San Carlos, United States)
Seniority
Architect · 10+ years exp
Visa
H-1B filings in 12 months: 9 · green card filings: 2

Confirmed on the employer's own hiring board on Oct 23, 2026. First seen by Alion on Feb 26, 2026. Vaxcyte scores A on the Alion truth index.

Overview
Company
Impact
Profile match
Vaxcyte is an American clinical-stage vaccine company based in San Carlos, California, developing broad-spectrum conjugate vaccines against bacterial diseases with a cell-free protein synthesis platform and modern synthetic chemistry. Its lead candidates are VAX-31, a 31-valent pneumococcal conjugate vaccine moving into a Phase 3 adult programme, and VAX-24, a 24-valent candidate in infant trials, with earlier programmes targeting Group A Strep and Shigella. It hires process, conjugation and analytical scientists, bioprocess and device engineers, validation and manufacturing systems specialists, commercial and market access leaders, pharmacovigilance and security staff.

Join our Mission to Protect Humankind!

Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance. 

WHAT  we do is every bit as important as HOW  we do it! Our work together is guided by four enduring core values:

*RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered.

*AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind.

*LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives.

*MODEL EXCELLENCE:  The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.

Summary:

The Associate Director, SEC Reporting & Technical Accounting will serve as a key contributor to the company’s external reporting and technical accounting function. Reporting to the Senior Director, Technical Accounting & SEC Reporting, this role will be highly hands-on, owning the preparation and execution of SEC filings and technical accounting analyses while also managing one direct report. 

This role is ideal for a technically strong accounting professional who enjoys operating in the details, partnering cross-functionally, and helping build processes in a growing public biotechnology company. 

Essential Functions:

SEC Reporting (Hands-On Execution) 

  • Own the preparation of quarterly and annual SEC filings, including Forms 10-Q, 10-K, and 8-K 
  • Prepare and/or review primary financial statements, footnotes, and related disclosures in accordance with U.S. GAAP and SEC requirements 
  • Draft and support MD&A disclosures, with emphasis on R&D, G&A, stock-based compensation, and other pre-revenue biotech-specific areas 
  • Coordinate the quarterly close-to-reporting process across Accounting, FP&A, Legal, and external auditors 
  • Support earnings release tie-outs and disclosure controls 

Technical Accounting 

  • Support technical accounting assessments and documentation for complex transactions, including: 
  • Collaboration, licensing, and R&D-related arrangements 
  • Equity and equity-linked financing transactions 
  • Other complex and other non-routine transactions 
  • Research new accounting standards and SEC guidance; assess applicability and implementation impact 
  • Draft clear, well-supported technical accounting memos and communicate conclusions to stakeholders 
  • Strong experience in ASC 842, including the identification, classification, and accounting of lease arrangements, as well as the preparation and review of related disclosures in compliance with U.S. GAAP

People Management 

  • Manage and mentor one direct report, providing coaching, review, and development support 
  • Review work products to ensure accuracy, quality, and adherence to timelines 
  • Foster strong execution discipline and continuous improvement within the reporting function 

Process Improvement & Scaling 

  • Help design and enhance scalable SEC reporting and technical accounting processes as the company grows 
  • Partner with cross-functional teams to ensure accounting and reporting considerations are incorporated into business decisions 
  • Support SOX and internal control documentation related to SEC reporting and technical accounting as applicable 

Requirements: 

Bachelor’s degree in Accounting or related field; CPA strongly preferred with a minimum 10 years of progressive accounting experience, including: Public accounting experience (Big 4 or national firm strongly preferred) and/or direct SEC reporting experience at a public company.  Other combinations of education and/or experience may be considered.

  • Strong technical knowledge of U.S. GAAP and SEC reporting requirements
  • Excellent written and verbal communication skills
  • Highly detail-oriented with strong execution skills
  • Comfortable operating in a fast-paced, evolving environment
  • Strong ownership mindset with the ability to balance deadlines and quality
  • Collaborative, proactive, and solutions-oriented 
  • Ability to work onsite 3 days per week required; and more often based on business needs. 

Location:  San Carlos, CA

Work Arrangement (may be adjusted based on business needs, job responsibilities, or changes to company policy): Hybrid (3 days per week onsite)

Compensation:

The compensation package will be competitive and includes comprehensive benefits and an equity component.

Salary Range: $184,000 - $215,000 (SF Bay Area). Salary ranges for non-California locations may vary.

Equal Opportunity

We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status.

Recruitment Fraud Notice

Please be aware of fraud or scams from individuals, organizations and/or internet sites claiming to represent Vaxcyte in recruitment activities. Vaxcyte has an established recruitment process for all positions prior to issuing an offer for employment and we will never extend unsolicited employment offers or ask candidates to provide financial or sensitive personal information as part of the application process. All legitimate communication from Vaxcyte will come from an official @vaxcyte.com email address. Qualified and interested candidates should apply to current openings at  vaxcyte.com/careers.

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