Manager Accounting , Inventory and Operations
Confirmed on the employer's own hiring board on Oct 29, 2026. First seen by Alion on Oct 14, 2026. Vaxcyte scores A on the Alion truth index.
Join our Mission to Protect Humankind!
Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.
WHAT we do is every bit as important as HOW we do it! Our work together is guided by four enduring core values:
*RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered.
*AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind.
*LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives.
*MODEL EXCELLENCE: The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.
Summary:
The Manager Accounting , Inventory and Operations role will help manage Vaxcyte’s cost accounting functions, including standard costing, inventory valuation, and manufacturing variance analysis. This role also owns the full manufacturing accrual process for the Manufacturing Accounting Team - maintaining accrual trackers, preparing monthly accrual journal entries, reconciling manufacturing general ledger accounts, and preparing manufacturing flux analysis. The Manager Accounting Inventory and Operations role partners closely with Supply Chain and FP&A to ensure accurate cost data, drive margin improvement initiatives, and maintain strong internal controls over inventory and cost of goods sold (COGS). The ideal candidate combines strong technical accounting skills with the ability to translate cost data into actionable business insights.
Essential Functions:
- Maintain and update standard costs for materials, labor, and overhead.
- Analyze and report on manufacturing variances (purchase price, usage, labor, and overhead) and partner with Supply Chain to explain and resolve root causes.
- Own the manufacturing accrual process end to end, including maintainingaccrual trackers by key vendors.
- Prepare monthly accruals for manufacturing vendors, ensuring costs are recorded in the appropriate period.
- Prepare journal entries related to manufacturing accruals, inventory, COGS, and manufacturing variances.
- Manageinventory valuation, reserves, scrap and obsolescence, and reconciliation processes across all locations.
- Reconcile manufacturing and cost-related general ledger accounts and ensure timely, accuratemonth-end close.
- Prepare monthly and quarterly flux analysis for inventory, COGSand manufacturing accrual accounts.
- Maintain and execute internal controls over inventory, standard costing, COGSand manufacturing accrualsin compliance with GAAP and Sarbanes-Oxley (SOX).
- Support quarterly external audits and SOX testing related to manufacturing, inventory, and cost accounting; managerequests, remediate deficiencies, and track corrective action plans.
- Investigate and resolve discrepancies identifiedin physical inventory counts and cycle counts.
- Support ERP and system enhancements related to inventory and cost accounting.
- Additionaltasks and responsibilities as assigned.
Requirements:
- Bachelor’s degree in Accounting, Finance, or relatedfield.
- 7+ years of progressive cost accounting experiencein abiotechmanufacturing environment, including contract manufacturing. Other combinations of education and/or experience may be considered.
- Experience with product costing in SAP S/4 Hana required.
- Strong understanding of standard costing, variance analysis, and inventory accounting under GAAP.
- Advanced Excel skills.
- Strong analytical, problem-solving, and communication skills.
- CPAorCMAcertificationpreferred.
- Experience working in a public company (SEC-reporting) environment preferred.
- Attention to detail and accuracy.
- Strong business acumen and ability to translate data into insights.
- Cross-functional collaboration and influence.
- Process improvement mindset.
- Ability to managecompeting priorities and deadlines.
Reports to: Associate Accounting Director, Manufacturing
Location: San Carlos, CA
Work Arrangement (may be adjusted based on business needs, job responsibilities, or changes to company policy):
Hybrid (minimum of 3 days per week onsite)
Compensation: The compensation package will be competitive and includes comprehensive benefits and an equity component.
Salary Range: $145,000- $169,000 (SF Bay Area). Salary ranges for non-California locations may vary.
Equal Opportunity
We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status.
Recruitment Fraud Notice
Please be aware of fraud or scams from individuals, organizations and/or internet sites claiming to represent Vaxcyte in recruitment activities. Vaxcyte has an established recruitment process for all positions prior to issuing an offer for employment and we will never extend unsolicited employment offers or ask candidates to provide financial or sensitive personal information as part of the application process. All legitimate communication from Vaxcyte will come from an official @vaxcyte.com email address. Qualified and interested candidates should apply to current openings at vaxcyte.com/careers.