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Salary
$156k – $234k per year
Location
Hybrid (Boston, United States)
Seniority
Architect · 8+ years exp
Visa
H-1B filings in 12 months: 174 · green card filings: 21
Employment
Full-Time

Confirmed on the employer's own hiring board on Oct 22, 2026. First seen by Alion on Oct 20, 2026. Vertex Pharmaceuticals scores A on the Alion truth index.

Overview
Company
Impact
Profile match
Vertex Pharmaceuticals is an American biotechnology company that discovers, develops and sells medicines for serious diseases, best known for its cystic fibrosis modulators Trikafta, Kalydeco, Orkambi and Symdeko and the CRISPR-based gene-edited therapy Casgevy for sickle cell disease and beta thalassemia. Founded in 1989, it also markets the non-opioid pain medicine Journavx and has programmes in kidney disease, type 1 diabetes and pain, with research sites in Boston, San Diego and London. The company is headquartered in Boston, Massachusetts, United States.

Job Description

General Summary:

The Project Management Associate Director role is an exciting opportunity to lead transformational projects that will streamline Supply Chain processes by leveraging digitization and AI. The incumbent will be responsible for the integration, creation and execution of multiple complex project and program plans. By partnering closely with leadership, SMEs and cross-functional team members, the incumbent will develop and maintain fully integrated project plans to ensure that deliverables are successfully executed, are in accordance with project objectives, and are within budget.

The incumbent is also responsible for comprehensive communication with leadership and across functions, including status reporting, risk management and escalation of issues, and identification of acceleration opportunities. Responsibilities include establishing Supply Chain departmental governance and creating, implementing, and sharing standardized and effective project management tools and processes.

The incumbent will be held accountable for project and program timelines and deliverables and successful execution of program governance.

Key Duties and Responsibilities:

  • Independently leads teams for multiple, complex projects
  • Inspire teams to think outside the box of what has already been done
  • Partner with Digital Technology and Engineering (DTE) to identify opportunities to leverage digital data, automation and AI as project deliverables are defined.
  • Develops and gain consensus for project plans, budgets, goals, and logistics.
  • Interact with and influence with functional areas outside of Supply Chain
  • Proactively conduct complex scenario analyses and provides recommendations on alternative plans, along with the associated assumptions and risks, to teams and leadership.
  • Report to leadership program information such as progress on deliverables and milestones, progress toward realization of project benefits and degree of adoption of changes triggered by the project (i.e. process changes).
  • Compiles succinct reports and prepare minutes for select internal meetings; methodically tracks action items, and finds new ways to stay abreast of these multi-dimensional tasks
  • Maintains frequent communication with the network of cross-functional internal and external stakeholders so that all parties are aware of current program status, issues, contingencies, and milestones
  • Contributes to the best practices of project management to support the continued success and evolution of the department
  • Develops tools for project management, project benefit measurement, Return on Investment projection and reporting, and promoted and coordinates the use of these tools by the department.

Knowledge and Skills:

  • Specialized, in-depth knowledge of project planning principles and tools (such as charters, project interdependency matrices, business case formats, ROI calculations and change management tools)
  • Experience managing projects in pharmaceutical industry
  • Significant experience working with MS project and Smartsheet required.
  • Highly skilled at formulating and delivering presentations to senior managers
  • Highly effective verbal and written communication skills.
  • Able to communicate complex ideas across functional boundaries, gain alignment and persuade individuals and teams to take action.
  • Significant experience in managing complex project teams and personnel
  • Skilled at coaching and mentoring other professionals, maintaining procedural and ethical standards and cultivating healthy team morale
  • Able to manage a large portfolio of complex projects effectively, ensuring alignment with leadership, departmental strategy, department goals and corporate goals

Education and Experience:

  • Incumbent requires a Bachelor's degree
  • Typically requires 8 years of work experience, or the equivalent combination of education and experience, in project management

At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Pay Range:

$155,700 - $233,500

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:

1. Hybrid: work remotely up to two days per week; or select

2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Hybrid

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected]

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