1,998,403open jobs
118,185companies
247,685added this week
Browse all
Salary
$205k – $275k per year
Location
In office (Seattle)
Seniority
Senior · 5+ years exp
Visa
H-1B filings in 12 months: 3 · for this role: 1

Confirmed on the employer's own hiring board on Oct 27, 2026. First seen by Alion on Jun 11, 2026. Xaira Therapeutics scores B on the Alion truth index.

Overview
Company
Impact
Profile match
Xaira Therapeutics uses generative models for protein design and drug discovery. It launched with one of the largest initial funding rounds in the sector. The company combines machine learning research with wet laboratory biology.

About Xaira Therapeutics

Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London.

About the Role

We are seeking a Senior Software Engineer to join our Platform team to design, build, and deploy the AI infrastructure that powers our world-class research team.  In this role, you’ll collaborate closely with AI Scientists and other engineers to enable the effective use of thousands of GPUs for training and inferencing cutting-edge biological foundation models.

This role spans a range of problems and skillsets, ranging from MLOps of cutting-edge GPU clusters, to backend engineering of control plane APIs.  Our ideal candidate has an opinion about slurm or kubernetes for model training, cares about maximizing bandwidth from the storage subsystems to the GPU, and can build the API paved path for submitting training jobs that are able to dispatch to multiple clusters.

What You Will Do

  • Develop and improve our model training system, responsible for dispatching distributed training jobs to clusters across multiple clouds.
  • Deploy storage subsystems that improve dataset management and throughput for training datasets.
  • Build evaluation infrastructure that enables easy execution and tracking.
  • Build base tooling for integrating model training with other internal infrastructure, such as telemetry, experiment tracking, and checkpointing.
  • Prior experience with biology is not required - we will teach what you need to know.  You’ll get to go in the lab, and for our ideal candidate, this should be a perk, not a chore!

Preferred Skills and Qualifications

  • Degree in Computer Science, Machine Learning, Computational Biology, or a related field.
  • 5+ years of industry experience building and deploying ML systems in production environments
  • Experience leading technical projects and driving cross-functional execution.
  • Strong programming skills in Python.
  • Experience with infrastructure/ops tools such as Terraform, Ansible.
  • Experience with deep learning frameworks such as Torch, Jax.
  • Solid understanding of machine learning
  • Experience with the infrastructure needs of large-scale model training.
  • Strong problem-solving skills and ability to work in a collaborative, multidisciplinary environment.

Compensation

We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants. We offer a competitive package that includes base salary, bonus, and equity. The base pay range for this position is expected to be $205,000 - $275,000 annually with a total cash compensation up to $235,000 - $325,000; however, the compensation offered may vary depending on the market, job-related knowledge, skills and capabilities, and experience.

Xaira Therapeutics an equal-opportunity employer. We believe that our strength is in our differences. Our goal to build a diverse and inclusive team began on day one, and it will never end.

TO ALL RECRUITMENT AGENCIES: Xaira Therapeutics does not accept agency resumes. Please do not forward resumes to our jobs alias or employees. Xaira Therapeutics is not responsible for any fees related to unsolicited resumes.

Free account
Stop reading job ads. Get the ones that fit.
One free account turns this page into a shortlist built around your stack, your level and your pay.
Match on every job. Stack, seniority, pay and location, scored against your profile.
1,998,403 open roles. Read straight off company career pages, refreshed every day.
Unlimited applications. Every one you send is tracked in one place, on-site or on a company board.
3 tailored CVs a month. Rewritten for the exact job you are applying to. Included free.
Create a free account Continue with Google
Free forever. No card. Under a minute.

Your match

How well do you fit this role?
Two answers are enough for a real match. No account needed.
Check my fit
Answers stay in this browser until you create an account.

Recommended for you based on this role

AI/ML
Similar stack
Same company
Seattle
$154k – $199k per year • In office • 7+ years exp • Bachelor's Degree • United States
AI/ML
NCCL
InfiniBand
DevOps
Red Hat
SLURM
Docker
Kubernetes
Ubuntu
HPC
Linux
Apply
$180k – $240k per year • Equity 0.5–1% • In office • Full-Time • 2+ years exp • San Francisco
AI/ML
LLM
DevOps
AWS
Apply
$128k – $273k per year • Equity • In office • Full-Time • 12+ years exp • Bachelor's Degree • Mahwah
Databases
PostgreSQL
Neo4j
Google BigQuery
AI/ML
LangGraph
LangChain
Model Context Protocol
Vertex AI
Embeddings
Function Calling
AI Agents
Langfuse
Gemini
LLM
RAG
OpenAI
Anthropic
LLMOps
Human-in-the-Loop
Knowledge Graph
DevOps
Rest API
Terraform
GCP
OpenTelemetry
CI/CD
Git
Kubernetes
Google GKE
Google Cloud Run
IAM
Cybersecurity
Least Privilege
Apply
$130k – $207k per year • In office • Full-Time • 7+ years exp • Master's Degree • Irvine
Python
AI/ML
Scikit-learn
Multimodal AI
Transformers
TensorFlow
PyTorch
Time Series
Explainable AI
Machine Learning
DevOps
GCP
Azure
AWS
Robotics
Sensor Fusion
MedTech
Design Controls
Verification & Validation
Apply
AI Engineer - Data 8 hours ago
≈ $149k – $297k per year (Estimated) • In office • Full-Time • 10+ years exp • Bachelor's Degree • Atlanta
Databases
Databricks
AI/ML
Copilot
Claude
Model Context Protocol
LLM
RAG
LLM Guardrails
Apply
≈ $25k – $63k per year (Estimated) • In office • 3+ years exp • Master's Degree • Shanghai
Python
Go
Java
SQL
Scala
Databases
Snowflake
Databricks
Amazon Redshift
Trino
AI/ML
Spark
Machine Learning
DevOps
AWS
Docker
Kubernetes
Analytics
A/B Testing
Apply
DevOps Engineer 4 days ago
≈ $18k – $42k per year (Estimated) • Hybrid • Full-Time • 5+ years exp • India
Python
DevOps
Terraform
Ansible
GitHub Actions
OpenTelemetry
Datadog
Prometheus
Azure
CI/CD
AWS
Docker
Kubernetes
Grafana
Configuration Management
Amazon EKS
Azure AKS
AWS Lambda
Amazon EC2
Incident Management
SLI/SLO/SLA
Amazon S3
IAM
Amazon ECS
Amazon CloudWatch
API Gateway
Linux
Cybersecurity
Snyk
SonarQube
Trivy
SOC 2
Apply
In office • Full-Time • 3+ years exp • Bachelor's Degree • Zurich
DevOps
Terraform
Ansible
OpenShift
Helm
Prometheus
GitLab CI
Azure
CI/CD
ArgoCD
Kubernetes
Grafana
Platform Engineering
Azure AKS
Apply
Systems Architect 4 days ago
$140k – $175k per year • Hybrid • 8+ years exp • Bachelor's Degree • West Bend
JavaScript
TypeScript
C#
DevOps
Azure DevOps
Azure
CI/CD
Kubernetes
GitHub
Cybersecurity
OWASP Top 10
OWASP ASVS
OWASP SAMM
STRIDE
Zero Trust
Least Privilege
Threat Modeling
Microsoft Entra ID
OWASP
Apply
$113k – $189k per year • In office • Nationals only • 4+ years exp • Bachelor's Degree • Centennial
AI/ML
LLMOps
DevOps
CI/CD
AWS
Kubernetes
Bamboo
Amazon EKS
GitLab
Cybersecurity
SonarQube
Management
Agile
Scrum
Apply
$120k – $180k per year • In office • Internship • Master's Degree • Seattle • South San Francisco
AI/ML
PyTorch
Machine Learning
Apply
$170k – $240k per year • In office • South San Francisco
Python
AI/ML
JAX
Multimodal AI
PyTorch
Self-Supervised Learning
DevOps
CI/CD
Apply
$227k – $295k per year • In office • Bachelor's Degree • South San Francisco
Python
AI/ML
Fine-tuning
JAX
Multimodal AI
Function Calling
AI Agents
TensorFlow
PyTorch
LLM
RAG
Knowledge Graph
Interpretability
Multi-Agent Systems
Machine Learning
Apply
$212k – $265k per year • In office • PhD • South San Francisco
Python
AI/ML
Multimodal AI
TensorFlow
PyTorch
Self-Supervised Learning
Machine Learning
Apply
$198k – $308k per year • In office • PhD • South San Francisco
AI/ML
PyTorch
Machine Learning
Apply
$184k – $249k per year • Equity • In office • Full-Time • 6+ years exp • Master's Degree • Seattle • Arlington • New York
Python
Java
C++
AI/ML
Machine Learning
Apply
$44k – $58k per year • In office • Internship • Seattle
Apply
≈ $180k – $336k per year (Estimated) • In office • 8+ years exp • Bachelor's Degree • Seattle
C++
AI/ML
Vertex AI
TPU
DevOps
GCP
Apply
≈ $40k – $85k per year (Estimated) • In office • Part-Time • 2+ years exp • Seattle
Apply
$86k – $124k per year • In office • 3+ years exp • Bachelor's Degree • Phoenix • Chicago • Denver • Seattle • Saint Louis
Apply
See all jobs
This is one of many
1,998,403 more open roles from verified company boards, updated every day.