368,530open jobs
9,432companies
50,439added this week
Browse all
Salary
$149k – $295k per year (Estimated)
Location
In office (San Francisco)
Seniority
Staff
Employment
Full-Time
Overview
Company
Impact
Profile match
COMPANY RESEARCH CLOUD Zyphra Cloud Login Two sides. Two sides.

Zyphra is an artificial intelligence company based in San Francisco, California.

The Role:

As a Lead Frontend Engineer, you’ll lead the design and development of the user-facing side of our agentic system, shaping how users interact with AI across their desktop, browser, and filesystem. You’ll work across interface design, component libraries, and frontend infrastructure to craft seamless, accessible, and intuitive user experiences. You’ll work closely with engineers, ML researchers, and backend teams to bring intelligent agents to life in a way that’s beautifully simple and deeply useful.

You’ll Work Across:

  • Design and development of browser-based and desktop interfaces

  • Building and maintaining component libraries and styling systems

  • Researching and refining user flows based on real-world usage and feedback

  • Prototyping and implementing UI features in collaboration with ML, backend, and systems teams

  • Making a complex AI product feel simple, accessible, and empowering for a wide range of users

What We're Looking For / Requirements:

  • Strong frontend engineering skills with fluency in HTML, CSS, and JavaScript/TypeScript

  • Experience with modern frontend frameworks such as React

  • Demonstrated attention to UI detail and usability, with a user-first mindset

  • Ability to prototype and iterate quickly, both in code and with design tools like Figma

  • Experience designing and developing responsive, accessible, and high-performance interfaces

  • Strong intuition for HCI principles, accessibility, and visual clarity

  • Excellent collaboration and communication skills-especially with engineers, designers, and ML researchers

Qualifications / Additional Skills:

  • Experience designing or building browser extensions or desktop applications (e.g., Electron, Tauri)

  • Experience with mobile platforms and responsive design (not required but helpful)

  • Prior work on products involving complex workflows, automation, or agentic behavior

  • Interest or experience in backend development, APIs, or AI systems to better interface with the full stack

  • Familiarity with accessibility standards and inclusive design best practices

  • A track record of launching polished and user-loved products

  • Passion for systems-level thinking: building reusable design systems, libraries, and scalable patterns

  • A clear, opinionated eye for elegant design and user delight

Why Work at Zyphra:

  • Our research methodology is grounded in methodical, step-by-step approaches to ambitious goals. Both deep research and engineering excellence are equally valued

  • We strongly value new and crazy ideas and are very willing to bet big on new ideas

  • We move as quickly as we can; we aim to minimize the bar to impact as low as possible

  • We all enjoy what we do and love discussing AI

Benefits and Perks:

  • Comprehensive medical, dental, vision, and FSA plans

  • Competitive compensation and 401(k) plan

  • Relocation and immigration support on a case-by-case basis

  • In-office snacks and meals provided

  • Unlimited PTO and company holidays

  • In-person team in San Francisco with a collaborative, high-energy environment

Free account
Stop reading job ads. Get the ones that fit.
One free account turns this page into a shortlist built around your stack, your level and your pay.
Match on every job. Stack, seniority, pay and location, scored against your profile.
368,530 open roles. Read straight off company career pages, refreshed every day.
Unlimited applications. Every one you send is tracked in one place, on-site or on a company board.
3 tailored CVs a month. Rewritten for the exact job you are applying to. Included free.
Create a free account
Free forever. No card. Under a minute.

Your match

How well do you fit this role?
Two answers are enough for a real match. No account needed.
Check my fit
Answers stay in this browser until you create an account.

Recommended for you based on this role

Similar stack
Same company
San Francisco
$54k – $175k per year (Estimated) • Remote • Full-Time
JavaScript
Node JS
TypeScript
Frontend
React.js
Sass
DevOps
AWS
CI/CD
Docker
Kubernetes
Rest API
Apply
$35k – $113k per year (Estimated) • Remote • Full-Time
JavaScript
Node JS
TypeScript
Frontend
React.js
Sass
DevOps
AWS
CI/CD
Docker
Kubernetes
Rest API
Apply
$35k – $116k per year (Estimated) • Remote • Full-Time
JavaScript
Node JS
TypeScript
Frontend
React.js
Sass
DevOps
AWS
CI/CD
Docker
Kubernetes
Rest API
Apply
$61k – $200k per year (Estimated) • Remote • Full-Time
JavaScript
Node JS
TypeScript
Frontend
React.js
Sass
DevOps
AWS
CI/CD
Docker
Kubernetes
Rest API
Apply
$54k – $176k per year (Estimated) • Remote • Full-Time
JavaScript
Node JS
TypeScript
Frontend
React.js
Sass
DevOps
AWS
CI/CD
Docker
Kubernetes
Rest API
Apply
$214k – $400k per year • Remote/Hybrid • 1+ year exp • Bachelor's Degree • San Francisco
C++
JavaScript
Python
SQL
TypeScript
AI/ML
AI Agents
Frontend
Angular
DevOps
CI/CD
Apply
$180k – $324k per year (Estimated) • In office • Full-Time • Master's Degree • San Francisco
AI/ML
AI Agents
Claude
Cursor
Fine-tuning
Multimodal AI
Apply
$158k – $345k per year (Estimated) • In office • Full-Time • San Francisco
Python
AI/ML
PyTorch
RAG
Reinforcement Learning
Pre-training
Apply
$161k – $352k per year (Estimated) • In office • Full-Time • San Francisco
Python
AI/ML
Fine-tuning
PyTorch
Reinforcement Learning
Synthetic Data
DPO
Post-training
SFT
Apply
$157k – $344k per year (Estimated) • In office • Full-Time • San Francisco
Python
AI/ML
PyTorch
Pre-training
Apply
$223k – $424k per year (Estimated) • In office • Bachelor's Degree • San Francisco
AI/ML
AI Agents
LLM
Recommender Systems
Apply
$83k – $188k per year (Estimated) • In office • 2+ years exp • San Francisco
Python
AI/ML
AI Agents
LLM Guardrails
Model Context Protocol
DevOps
Terraform
Cybersecurity
Crowdstrike
GDPR
Least Privilege
Okta
SentinelOne
Management
Google Workspace
Slack
Apply
$171k – $273k per year • In office • Full-Time • 8+ years exp • PhD • San Francisco • Washington
AI/ML
A2A
Agentforce
AI Agents
Model Context Protocol
DevOps
AWS
GCP
Marketing
Salesforce
Apply
Security GRC Analyst 2 hours ago
$119k – $268k per year (Estimated) • Remote/Hybrid • 4+ years exp • Bachelor's Degree • San Francisco
AI/ML
Ignite
PyTorch
Cybersecurity
ISO 27001
NIST CSF
SOC 2
Apply
$173k – $260k per year • In office • Full-Time • PhD • San Francisco
JavaScript
Node JS
Python
Python
Celery
Django
Flask
Databases
RabbitMQ
Redis
AI/ML
Agentforce
AI Agents
DevOps
Akamai
AWS
CI/CD
Cloudflare
CloudFormation
Helm
Jenkins
Kubernetes
Spinnaker
Terraform
Marketing
Salesforce
Apply
See all jobs
This is one of many
368,530 more open roles from verified company boards, updated every day.