EpiCypher

Beyond RNA-seq: Applying CUT&RUN to Decode Drug Resistance and Inform Rational Combination Therapies Key Takeaways:RNA-seq and ATAC-seq reveal transcriptional rewiring associated with cancer drug resistance; however, they only indirectly implicate the res

/PRNewswire/ -- EpiCypher and New England Biolabs (NEB) today announced an expanded strategic partnership to co-develop next-generation tools for...

Fiber-seq Provides a More Complete View of the Human Brain Epigenome Fiber-seq: A Solution to Uncover Unmapped Epigenomic RegionsChromatin profiling assays employed to detect accessible chromatin regions represent a widely used means of generating genome-

Interrupting the epigenetic programs that drive tumor growth is a promising avenue for cancer therapy, and NSD2 is emerging as a compelling target. However, robust technologies are needed to define the mechanism of action of NSD2-targeted therapeutics, pa

CUT&RUN and CUT&Tag have become gold-standard methods for profiling protein-DNA interactions, offering high resolution, low background, and efficient sequencing. While these assays dramatically simplified experimental workflows, data analysis has remained

Durham, NC - Oct. 16, 2025 (The Scientist) - Winning a spot in the 2025 Top Innovations contest's Lab Research Tools category, the CUTANA meCUT&RUN kit harnesses engineered proteins to capture DNA methylation sites at scale.DNA methylation is an epigeneti

Epigenetic mechanisms shape nearly every aspect of neurobiology-from guiding early neural development to regulating plasticity, cognition, and responses to injury or disease. Interest in chromatin profiling in neuroscience continues to grow, as researcher

Funding challenges are a reality for many researchers, and we want to make sure innovation doesn't slow down because of it. That's why our team has introduced major updates to CUTANA CUT&Tag assays - making them more streamlined, affordable, and accessibl

How do cells control when and where genes are expressed? The answer lies in a complex interplay of regulatory proteins that govern chromatin accessibility and architecture. These processes establish cell identity and maintain genome stability, and when di

Tardigrades are remarkable in their ability to survive extreme environments. The damage suppressor (Dsup) protein is thought to contribute to their extreme resistance to reactive oxygen species (ROS) generated by irradiation. Here we show that expression