Fight Aging!

You might recall that the Horvath epigenetic clock did not exhibit differences in biological age when comparing twins, given one twin that is sedentary versus one twin that is active. I blamed that on the epigenetic clock at the time, and it is certainly

The study noted here provides an interesting addition to the debate over whether time spent sitting is harmful to health independently of its contribution to time spent being sedentary. Time spent sitting increases mortality, while time spent active or un

Here find the first draft of a proposal regarding the best way forward at the present time to accelerate progress towards the development of diverse, effective rejuvenation therapies. The key is to use philanthropic funding to (a) prove efficacy in low-co

Today's popular science article is a tour of a few of the higher profile lines of research and development relevant to treating aging as a medical condition. The state of the field has changed greatly over the last decade, not least of these changes being

Ordinary people don't pay much attention to the science of aging. Ordinary people don't keep an eye on the longevity industry or read scientific papers or donate funds to non-profits supporting important research. Ordinary people don't carefully and ratio

Medical research and development in the context of aging has, like all other medicine, been dominated for a long time by a model in which a single disease is identified by symptoms and then treated. In the context of infectious disease and inherited condi

In recent years more careful consideration of epidemiological data has pointed to there being no health advantage to moderate alcohol consumption. Many past studies were looking at a form of alcohol consumption, such as moderate wine intake, that correlat

A common factor in calorie restriction, intermittent fasting, and time-restricted feeding is time spent in a state of hunger. More time spent hungry may be better, up to a point. The signaling associated with hunger upregulates cellular maintenance proces

A eusocial species is divided into specialized castes. The reproductive caste (queens) exhibits a much longer life span than members of the other non-reproductive castes (workers), yet the members of all castes are genetically similar. Researchers here di

Fasting produces benefits to health that are meaningful in comparison to the cost of this intervention - it is free, and the health benefits are reliable and repeatable. When it comes to improved metabolism and long-term health benefits, no medical techno