insitro
insitro.com
Actively hiring
Bioinformatics
Drug Discovery
Drug Discovery AI
As featured in
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News
Technologies
Salaries
Products
People
Growth
Offices
Jobs
Financials
Funding and backers
Total raised
$143M
1 round on record
Latest round
$143M
Venture round · May 2020 · 6 yr ago
Team
210
US Form 5500 (plan participants) · Dec 2025 · -27% in a year
Hiring now
12
+2 posted in 30 days
Backers
5
Andreessen Horowitz, ARCH Venture Partners
The money's age
Long since its last round
76 months since the last round · and hiring
Momentum
22/100
hiring for its size, in the news
Last sign of life
this month
a posting or a news item
The story so fareach stage dated by its source: the company's releases, the press, registers, filings
Sep 8
New executive insitro Appoints Hideo Makimura as Chief Medical Officer to Lead Its Transition to a Clinical-Stage Company · insitro.com
Feb 26
New executive insitro Appoints Joe Hand as Chief People Officer to Advance Talent Strategy for Next Stage of Development · insitro.com
Jan 12
Acquisition insitro to Acquire CombinAbleAI to Complete its Full Stack, Modality-Agnostic AI Platform for Drug Discovery and Design · insitro.com
2025
Team shrank to 210 was 289 · US Form 5500 (plan participants)
Sep 7, 2025
Partnership insitro Partners with Lilly to Build First-in-Kind Machine Learning Models to Advance Small Molecule Drug Discovery · businesswire.com
May 8, 2025
Layoffs Insitro, an AI biotech founded by Daphne Koller, lays off staff · STAT
Nov 30, 2022
New executive insitro Appoints Philip Tagari, Industry-Leading Scientist and Drug Hunter, as Chief Scientific Officer · businesswire.com
May 27, 2020
Raised a round Venture round $143M
2018
Founded
Tractionpublic signals, read monthly
Web presence
top 0.31%
of 133.2M domains by links, Common Crawl
Funding rounds
| Round | Date | Amount | Investors | Source |
|---|---|---|---|---|
| Venture round | May 2020 | $143M | — | forbes.com |
Registers and programsofficial lists and records that name the company
| Legal entity | Insitro, Inc. | SEC Form D |
Founders and leadersfrom filings, registers and the company's site
Daphne KollerExecutive Officer, DirectorSEC Form D
Duane ValzExecutive OfficerSEC Form D
Mary RozenmanExecutive OfficerSEC Form D
Backed byfrom the funds' portfolios and accelerator catalogs
Andreessen Horowitz 
ARCH Venture Partners 
Foresite Capital 
GV Investors in similar startupsfunds that back the companies most like this one
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How insitro hires
Truth index
B 83/100
Median time to fill
96 days
Ghost roles
0%
Stale roles
50%
Reposted roles
0%
insitro scores B on the Alion truth index (A is best, E worst), measured over 4 open roles re-checked against its own hiring board: 0% look like ghost listings, 50% have gone stale and 0% are the same role posted again. Its roles close in a median of 96 days. It measures how much of what this employer publishes turns into a real, finite search - not the employer as a workplace. How the index is computed
Visa sponsorship
- United States · H-1B filings in 12 months: 11 · green card filings: 2
News
insitro Appoints Hideo Makimura as Chief Medical Officer to Lead Its Transition to a Clinical-Stage Company
Accomplished physician-scientist and drug developer brings deep clinical development expertise as insitro prepares to advance its pipeline into the clinic SOUTH SAN FRANCISCO, Calif. - Sept. 8, 2026 - insitro, the AI therapeutics company built on causal b
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Report
Introducing Deep Phenotype: A New Home for Perspectives on AI, Biology, and the Future of Drug Discovery
At insitro, we're building more than AI-powered drug discovery technologies. We're working to fundamentally reshape how medicines are discovered through causal human biology, machine learning, and data-driven science. Today, we're excited to share Deep Ph
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Report
insitro Presents New Data Demonstrating Its AI-Discovered MASH Candidate Shows Anti-Fibrotic Signal Beyond Liver-Fat Reduction at the American Diabetes Association 86th Scientific Sessions
Findings from insitro's lead therapeutic CTRO-1013 program demonstrate that liver-targeted silencing of IRS1 lowered circulatory biomarkers associated with fibrosis progression and hepatocyte injury in an industry-standard fibrogenic preclinical mouse mod
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Report
insitro Presents New Data Demonstrating Its AI-Discovered MASH Candidate Shows Anti-Fibrotic Signal Beyond Liver-Fat Reduction at the American Diabetes Association 86th ...
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Report
Rewriting the Playbook for ALS Drug Development
Amyotrophic Lateral Sclerosis (ALS) presents one of the most formidable challenges in medical science. For too long, the search for effective treatments has been hampered by a temptation to revisit familiar hypotheses and established biological pathways.
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Report
insitro and Bristol Myers Squibb Collaboration Expanded with Nomination of New Targets
Collaboration expands to include two additional therapeutic targets for the treatment of ALS discovered via insitro's AI-driven Virtual Humanplatform Joint effort focuses on identifying key biological drivers to deliver disease-modifying interventions for
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Report
insitro Appoints Joe Hand as Chief People Officer to Advance Talent Strategy for Next Stage of Development
Seasoned life sciences executive brings deep expertise in scaling organizations and enterprise leadership through transformative growth SOUTH SAN FRANCISCO, Calif. - Feb 26, 2026 - insitro, the AI therapeutics company built on causal biology, today announ
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Report
Mapping the Genetics of Brown Fat
How insitro unlocked population-scale human genetics in a tissue that has resisted measurement for decades - and what it reveals about peripheral approaches to metabolic disease The Furnace We Couldn't SeeThe human body contains a type of fat tissue engin
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Report
insitro Completes First AI-Enabled Human Genetics Study of Brown Adipose Tissue, Shares Differentiated Targets with Anti-Obesity Effects
AI-enabled brown adipose tissue (BAT) phenotype unlocks population-scale human genetic discovery BAT-01 knockdown drives 15% body-weight reduction in preclinical models through peripheral adipose beiging, preserving lean mass Key findings presented at the
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Report
SF Healthcare Week: insitro CEO Daphne Koller on how AI is hitting "escape velocity" for finding causal targets for disease and speeding up drug development
The post SF Healthcare Week: insitro CEO Daphne Koller on how AI is hitting "escape velocity" for finding causal targets for disease and speeding up drug development appeared first on insitro.
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Tech stack
Technologies named in job postings at insitro over the last 12 months, by layer, with the share of postings for each.
Technologies in use
34
Postings analysed
17
Stack modernity
89/100AI adopter
Languages
Python35%
SQL12%
C#6%
Go6%
Frameworks & libraries
PyTorch12%
Dask6%
Keras6%
NumPy6%
Databases
PostgreSQL6%
Cloud & platforms
AWS18%
GCP12%
Kubernetes6%
Azure6%
AI & ML
Claude18%
LLM12%
ChatGPT6%
Gemini6%
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Full insitro tech stack
34 technologies · by team · pay by technology · changes · similar stacks
Salary insights
Compensation ranges based on this company's open jobs
Median
$233k
Typical range
$114k – $333k
Open positions
11
11
Jobs
Junior
18.2%
Senior
45.5%
Staff
18.2%
Architect
18.2%
| Level | Jobs | Median | Typical range |
|---|---|---|---|
| Junior | 2 | $127k | $114k – $140k |
| Senior | 5 | $262k | $194k – $298k |
| Staff | 2 | $208k | $183k – $233k |
| Architect | 2 | $282k | $231k – $333k |
Highest paying role
Vice President, Regulatory Affairs
$333k
Normalized to USD per year
All salaries at insitro
By role, level and city, against the market · 11 jobs with pay
People
Daphne Koller
Executive Officer, Director
Duane Valz
Executive Officer
Mary Rozenman
Executive Officer
Robert Nelsen
Director
Vijay Pande
Director
Names and roles come from public filings, company registers and the company's own site. Is this you? Correct or remove · How we handle this data
Growth
Hiring Momentum
61/100
Growing
Open positions
12
2 opened / 1 closed in 30 days
Median time-to-fill
73 days
faster than 18% of the market
ATS activity
Every ~3 hours
Today
Hiring Dynamics
+100%
Hiring Focus
The percentage next to each role is its share of the company's job openings over the last 90 days; the arrow shows the shift versus the previous period.
Backend
18% ▲
Science & Research
18% ▲
Data Science
9% ▼
Product
9% ▼
Finance
9% ▲
HR
9% ▲
Activity Timeline
Added Google Sheets to stack
Oct 2026
Added Dask to stack
Oct 2026
Added TypeScript to stack
Sep 2026
Added SQLAlchemy to stack
Sep 2026
Added Slack to stack
Sep 2026
Added PostgreSQL to stack
Sep 2026
Added Go to stack
Sep 2026
Added FastAPI to stack
Sep 2026
Added Docker to stack
Sep 2026
Added Django to stack
Sep 2026
Added Machine Learning to stack
Sep 2026
Added Agile to stack
Sep 2026
Offices
Where the company hires and what each office is for
Cities
1
Hiring now
1
Countries
1
Busiest office
South San Francisco
South San Francisco
United States
HQ
279 East Grand Avenue
12 open roles 11 posted in 90 days 50% engineering 50-200 est. staff $229k Avg Salary
hires for Backend, AI/ML, Data Science
279 East Grand Avenue, South San Francisco, California 94080
Jobs
$111k – $140k per year • Equity • Hybrid • Full-Time • 2+ years exp • South San Francisco
Python
Go
TypeScript
SQLAlchemy
FastAPI
Django
Databases
PostgreSQL
AI/ML
Multimodal AI
AI Agents
LLM
Agentic Workflows
Physical AI
Machine Learning
DevOps
GCP
AWS
Docker
Management
Slack
Apply
$183k – $194k per year • Equity • Hybrid • Full-Time • 3+ years exp • PhD • South San Francisco
Python
Multimodal AI
NumPy
Machine Learning
Apply
$191k – $233k per year • Equity • Hybrid • Full-Time • 6+ years exp • South San Francisco
Python
Dask
AI/ML
Multimodal AI
AI Agents
PyTorch
Ray
Physical AI
Machine Learning
DevOps
Kubernetes
Platform Engineering
Apply
$147k – $183k per year • Equity • Hybrid • Full-Time • 6+ years exp • Bachelor's Degree • South San Francisco
Python
SQL
C#
Multimodal AI
Physical AI
Machine Learning
Apply
≈ $173k – $330k per year (Estimated) • Equity • Hybrid • Full-Time • 2+ years exp • Master's Degree • South San Francisco
Python
SQL
Multimodal AI
Computer Vision
AI Agents
TensorFlow
Keras
PyTorch
Time Series Forecasting
Machine Learning
DevOps
Azure
AWS
Apply
Financials
Total raised
$143M
Latest round
Venture - Series Unknown
Funding rounds
1
Funding rounds
| Round | Announced | Amount | |
|---|---|---|---|
| Venture - Series Unknown | 2020 | $143M | Details |