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The power of live-cell imaging and single-particle tracking Super-resolution microscopy and particularly Single-Molecule Localization Microscopy (SMLM) are great for capturing molecular events within the nanometer scale resolution. Usually, high resolutio

Discover what DNA-PAINT modality works best for you DNA-PAINT (DNA Point Accumulation in Nanoscale Topography) enables scientists to visualize a large number of targets in a single sample and study single proteins with sub-20 nm resolutions. Its quantitat

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We've put together a one page, printable PDF to help you choose between the Nanoimager's key super-resolution microscopy techniques. It covers core techniques including dSTORM, PALM, SPT and smFRET. The post Which super-resolution technique is right for y

Understanding nanoscale biological structures like extracellular vesicles (EVs) and lipid nanoparticles (LNPs) is essential for advancing research in cell communication, targeted drug delivery, and nanomedicine. But analyzing these tiny, complex particles

Super-resolution Microscopy in Material Science Super-resolution microscopy (SRM) has emerged as a transformative tool enabling researchers to visualize and understand structures and processes at the nanoscale. SRM is well integrated in the field of biolo

Using targeting ligands for specific LNP delivery Targeting lipid nanoparticles (LNPs) to specific organs and tissues is a high-stakes high-reward challenge in modern biomedicine. Here we discuss the current landscape of loading LNPs with targeting ligand

The 2024 winners share how ONI's Nanoimager will help them quantify cancer EVs at the single vesicle and molecule levels Dolores Di Vizio, MD, PhD, is a Professor at Cedars-Sinai Medical Center, where she has been working on Large Oncosomes (LO) and Extra

Basel Super-Resolution Summit, December 2024 At the meeting point of Switzerland, France and Germany, Basel is a hub for biotechnology and pharma. It is not surprising, therefore, that our Super-Resolution Summit there was heavily focused on new technolog

Super-resolution approaches to study dynamic processes in cells Super-resolution microscopy is often associated with observing tiny details in cells that are fixed, or in other words, frozen in time and in space. These methods are extremely useful as they