Profluent
profluent.bio
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Overview
Profluent is a company founded in 2022 that trains large language models on protein sequences to design new functional proteins. It released OpenCRISPR-1, a gene editor designed entirely by a model and made freely available for ethical research and commercial use. The company works on editors, antibodies and enzymes that have no direct natural counterpart.
News
GEMMABio Awarded ARPA-H Funding to Pursue Innovative Base-editing Strategy for Rare Liver Diseases
- The goals of this project will be enabled through a partnership with Profluent Bio who will deploy its frontier AI models and its scalable base editor...
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Report
Lilly, AI biotech Profluent ink $2.25B pact in search of genetic medicine 'holy grail'
Weight loss giant Eli Lilly has penned a DNA editing deal with Profluent Bio, continuing its dealmaking spree as well as its commitment to artificial intelligence.
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Report
Eli Lilly enlists AI startup for next-generation gene editors
Eli Lilly deal with Profluent aims to go beyond CRISPR by using AI-designed enzymes to insert entire genes. If it works, it could reshape genetic medicine.
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Report
AI start-up Profluent nabs Lilly as first big pharma partner
AI start-up Profluent has signed a major alliance with pharma group Eli Lilly, worth up to $2.25bn, that will focus on gene-editing therapies.
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Technologies
Tech DNA
Python
PyTorch
CUDA
Triton
Google BigQuery
PostgreSQL
GCP
AWS
Azure
AI/ML
Python
GCP
PyTorch
AWS
Azure
CI/CD
Spark
Docker
Kubernetes
MLFlow
CUDA
CUDA Toolkit
Fine-tuning
Triton
Reinforcement Learning
FSDP
SFT
Pre-training
Post-training
Google BigQuery
PostgreSQL
Other
ETL/ELT
Stack modernity
71/100
How modern this stack is, based on technology relevance, AI adoption and the share of legacy tools.
In-demand technologies
PyTorch
5 jobs
Required
GCP
5 jobs
Required
Azure
4 jobs
Required
AWS
4 jobs
Required
CI/CD
3 jobs
Required
Python
3 jobs
Required
Spark
3 jobs
Required
MLFlow
1 job
Required
Salary medians are calculated from this company's open jobs and compared with the market.
Industry adoption
Python
18%
CI/CD
15%
Azure
14%
GCP
13%
AWS
13%
Kubernetes
11%
Share of companies in the same industry that use each technology.
Stack changes
Post-training
Aug 2026
Pre-training
Aug 2026
SFT
Aug 2026
FSDP
Aug 2026
ETL/ELT
Aug 2026
PostgreSQL
Aug 2026
Google BigQuery
Aug 2026
Reinforcement Learning
Aug 2026
Technologies recently added to or removed from this company's stack - a signal of tech migrations and new initiatives.
NVIDIA
Adobe
CrowdStrike
Cerebras Systems
Cohere
Fireworks AI
Growth
Hiring Momentum
38/100
Slowing
Open positions
7
0 opened / 0 closed in 30 days
ATS activity
Every ~22 hours
08/31/2026
Hiring Dynamics
0%
Hiring Focus
The percentage next to each role is its share of the company's job openings over the last 90 days; the arrow shows the shift versus the previous period.
AI/ML
100%
Activity Timeline
Added PostgreSQL to stack
Aug 2026
Added Google BigQuery to stack
Aug 2026
Added Reinforcement Learning to stack
Aug 2026
Added Triton to stack
Aug 2026
Added Spark to stack
Aug 2026
Added Python to stack
Aug 2026
Added Kubernetes to stack
Aug 2026
Added GCP to stack
Aug 2026
Added Fine-tuning to stack
Aug 2026
Added Docker to stack
Aug 2026
Added CUDA Toolkit to stack
Aug 2026
Added CUDA to stack
Aug 2026
Jobs
≈ $139k – $269k per year (Estimated) • Remote/Hybrid • 5+ years exp • Bachelor's Degree • Emeryville
MLFlow
PyTorch
DevOps
CI/CD
Apply
≈ $132k – $248k per year (Estimated) • Remote/Hybrid • 3+ years exp • Bachelor's Degree • Emeryville
Python
CUDA
CUDA Toolkit
Fine-tuning
PyTorch
Spark
Triton
FSDP
SFT
DevOps
AWS
Azure
Docker
GCP
Kubernetes
Analytics
ETL/ELT
Apply
≈ $156k – $299k per year (Estimated) • Remote/Hybrid • 7+ years exp • Bachelor's Degree • Emeryville
Python
Spark
DevOps
CI/CD
Apply
≈ $138k – $248k per year (Estimated) • Remote/Hybrid • 5+ years exp • Bachelor's Degree • Emeryville
Python
Google BigQuery
PostgreSQL
AI/ML
Spark
DevOps
CI/CD
GCP
Apply
≈ $134k – $293k per year (Estimated) • Remote/Hybrid • PhD • Emeryville
PyTorch
Reinforcement Learning
Post-training
DevOps
AWS
Azure
GCP
Apply
≈ $131k – $288k per year (Estimated) • Remote/Hybrid • PhD • Emeryville
PyTorch
Pre-training
DevOps
AWS
Azure
GCP
Apply
≈ $131k – $245k per year (Estimated) • Remote/Hybrid • 3+ years exp • PhD • Emeryville
PyTorch
DevOps
AWS
Azure
GCP
Apply