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Salary
≈ $111k – $214k per year (Estimated)
Location
In office (Juncos)
Seniority
Senior · 2+ years exp
Visa
H-1B filings in 12 months: 372 · for this role: 78 · green card filings: 113
Employment
Full-Time

Confirmed on the employer's own hiring board on Oct 18, 2026. First seen by Alion on Oct 16, 2026. Amgen scores B on the Alion truth index.

Overview
Company
Impact
Profile match
Amgen is an American biotechnology company founded in Thousand Oaks in 1980 that became one of the first firms to turn recombinant protein research into large commercial medicines. Its history rests on Epogen and Neupogen, and its current portfolio spans bone health with Prolia and Evenity, inflammation with Otezla and Tezspire, cardiovascular disease with Repatha, oncology including the bispecific antibody Blincyto, and a biosimilars business built on its own manufacturing capacity. The company is listed on Nasdaq, is a component of the Dow Jones Industrial Average, and expanded further into rare disease through its acquisition of Horizon Therapeutics.

Career Category

Information Systems

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. Amgen is advancing a broad and deep pipeline and portfolio of medicines to treat heart disease, obesity and obesity-related conditions, rare diseases, inflammatory conditions and cancer. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Sr. Associate IS Business System Analyst

What you will do

Let’s do this. Let’s change the world! In this vital role, you will partner with manufacturing and technology teams to deliver reliable, compliant, and innovative data solutions that support critical operations. You will help drive digital transformation, operational excellence, and data-driven decision-making through the effective use of PI Data Historian and related technologies.

  • Administer, configure, and maintain PI Data Historian platforms supporting Drug Substance and Drug Product operations, including equipment integration across manufacturing areas.
  • Collaborate with cross-functional teams to ensure effective integration between PI Data Historian and manufacturing systems, including MES, PCS, DCS, PLC, SCADA, and related technologies.
  • Coordinate with vendors and external support teams to troubleshoot and resolve application-related issues, ensuring system reliability and operational efficiency.
  • Lead and support technology project implementations and ongoing operational activities, including server deployment coordination, validation support, work order execution, and cybersecurity patch management.
  • Manage multiple medium-to-large cross-functional initiatives simultaneously, ensuring timely execution of milestones and delivery of business value.
  • Ensure compliance with cybersecurity, privacy, data integrity, and regulatory requirements through routine patching, security assessments, and adherence to established standards.
  • Serve as a Technology Subject Matter Expert (SME) in support of internal and external audits, inspections, and regulatory assessments.
  • Support the development and adoption of data analytics, data science, machine learning, and artificial intelligence capabilities to enhance business performance and decision-making.
  • Provide guidance and technical expertise on Informatics and Technology solutions, supporting business priorities and continuous improvement initiatives.
  • Collaborate with business, Technology, and Enterprise Architecture teams to support project portfolios, evaluate solution alternatives, and contribute to business case development.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The Sr. Associate IS Bus Sys Analyst professional we seek is an individual contributor with these qualifications.

Basic Qualifications:

Master’s degree

OR

Bachelor’s degree and 2 years of Information Systems experience

OR

Associate’s degree and 6 years of Information Systems experience

OR

High school diploma / GED and 8 years of Information Systems experience

Preferred Qualifications:

  • Bachelor’s degree in Engineering and/or Computer Science.
  • Experience administering and supporting Data Historian Systems, preferably OSI PI, including integration with manufacturing and process control systems such as PCS, DCS, PLC, SCADA, and related technologies.
  • Hands-on experience with PI System components, including PI Asset Framework (AF), PI Vision, Performance Equations, RT Reports, and other reporting and visualization tools.
  • Experience working with databases and data platforms, including SQL, Oracle, Databricks, and other relational database technologies.
  • Knowledge of data analytics, data science, statistical analysis, business intelligence, machine learning, and data visualization tools such as Tableau, Spotfire, Python, and R.
  • Demonstrated ability to collaborate effectively with business partners and cross-functional Technology teams to deliver solutions and drive projects from concept through implementation.
  • Experience working in Agile environments and applying Agile methodologies to project delivery and continuous improvement initiatives.
  • Understanding of cybersecurity principles and practices, including access management, vulnerability remediation, patch management, and system compliance.
  • Experience supporting the full application lifecycle, including administration, maintenance, enhancement identification, implementation, and ongoing operational support.
  • Strong verbal and written communication, presentation, and stakeholder management skills, with fluency in both English and Spanish.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

In addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

  • A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental & vision coverage, and life & disability insurance
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans and an annual site shutdown
  • Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer. We make all employment decisions without regard to race, color, religion, sex or any other characteristic protected by applicable law.

We provide reasonable accommodations to applicants and employees with disabilities, consistent with legal requirements. Please contact us to request accommodation.

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