Salary
$150k – $300k per year
Location
In office (San Francisco)
Employment
Full-Time
Confirmed on the employer's own hiring board on Nov 11, 2026. First seen by Alion on Sep 25, 2026.
Overview
Company
Impact
Profile match
Astraea automates SAPs, SDTM/ADaM, TLFs, Define-XML, QC, and FDA submission documents inside your environment. Sponsor-run software, not a CRO.
Backed by Y Combinator, Aligned Climate Capital
We are looking for a founding engineer who wants to build deeply technical AI systems in one of the most important and regulated industries in the world.
You will work directly with the founders to:
- Build agentic workflows for clinical trial automation
- Design reliable systems for document ingestion, data transformation, validation, and auditability
- Own core product surfaces across frontend, backend, data infrastructure, and AI orchestration
- Work closely with clinical teams to turn messy real-world workflows into production software
- Ship quickly while maintaining the rigor required for regulated healthcare environments
You might be a fit if you:
- Are an exceptional full-stack or backend engineer
- Care about building reliable, production-grade AI systems and can/have integrated into legacy systems in the past
- Move fast, take ownership, and like ambiguous technical problems
- Are excited by using AI to automate healthcare, clinical trials, or regulated data workflows
- Want to join at the earliest stage and help define the engineering culture
We care less about credentials and more about raw ability, taste, speed, and ownership. This is a high-agency founding role for someone who wants to build category-defining software.
- Send us any relevant information (resume, background, github)
- Saffron interview
- 30 min technical with Sanmay (CTO) and Eng
- Live coding session with Eng team
- 30 min culture interview
- Paid work trial on a realistic Astraea engineering problem. This is designed to evaluate how you think, build, communicate, and handle ambiguity. Can accomodate online if needed.
- Offer
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