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Salary
≈ $176k – $389k per year (Estimated)
Location
In office (San Francisco)
Visa
H-1B filings in 12 months: 2 · for this role: 1
Employment
Full-Time

Confirmed on the employer's own hiring board on Oct 24, 2026. First seen by Alion on Mar 6, 2026. Chai Discovery scores C on the Alion truth index.

Overview
Company
Impact
Profile match
Chai Discovery is a San Francisco research company founded in 2024 that builds foundation models for molecular structure and interaction prediction. Its Chai-1 model predicts complexes of proteins, small molecules, nucleic acids and antibodies, and was released for free non-commercial use alongside a commercial offering. The company is backed by OpenAI and Thrive Capital and targets the design of antibodies and other biologics.

About Chai Discovery

Chai Discovery builds the computer-aided design suite for molecules. Eli Lilly, GSK, Pfizer, Bristol Meyers, argenx and Novartis all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.

We train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.

We value diverse perspectives and are ready to find greatness in unexpected places.

About the role

We are hiring research scientists with outlier insight who can drive new avenues for the work we pursue. From pre-training large diffusion models and architecture design, to post-training and inference time scaling, we draw upon the best ideas from within our domain and across the field.

Our models have moved beyond protein structure prediction into real-world therapeutic engineering-and we have only just begun. Our team hails from physics, math, theoretical computer science, computational biology and related disciplines. Everyone is capable and self-sufficient, and everyone helps foster a highly collaborative and collegial environment.

Our view is that executing on a long-term research program requires bringing together the right people, with access to the best resources, aligned towards common objectives. And nothing is more essential to our mission and our business than the progress of our research.

About you

We are looking for researchers driven by impact and foundational progress. We index on sustained focus, rigor and results-people who get obsessed with hard problems and don't give up easily. Folks with a nose for tackling the right questions at the right time, alongside an ample dose of grit and curiosity.

We value academic training, research track record, and proven industry accomplishments; we are also more than willing to make a bet on rising talent. We look for engineering capability as well as literature fluency.

We offer

The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect & promote a culture of high velocity and ownership. We compensate our team accordingly.

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