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≈ $142k – $324k per year (Estimated)
Location
In office (San Francisco)
Visa
H-1B filings in 12 months: 2
Employment
Full-Time

Confirmed on the employer's own hiring board on Oct 31, 2026. First seen by Alion on Aug 29, 2026. Chai Discovery scores C on the Alion truth index.

Overview
Company
Impact
Profile match
Chai Discovery is a San Francisco research company founded in 2024 that builds foundation models for molecular structure and interaction prediction. Its Chai-1 model predicts complexes of proteins, small molecules, nucleic acids and antibodies, and was released for free non-commercial use alongside a commercial offering. The company is backed by OpenAI and Thrive Capital and targets the design of antibodies and other biologics.

About Chai Discovery

Chai Discovery builds the computer-aided design suite for molecules. Eli Lilly, GSK, Pfizer, Bristol Meyers, argenx and Novartis all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.

We train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.

We value diverse perspectives and are ready to find greatness in unexpected places.

About the role

We are building out our science team and looking to make a few key hires to anchor the effort, operating at the frontiers of both drug discovery and AI research.

You will be an advisor to some of the most important drug programs of our time, helping solve disease at scale. You will become an expert in our partners' scientific and therapeutic problems. You will operate as a power user who knows all the ins and outs of our technology, ensuring that our partners deploy our platform to maximum effect.

You will be our eyes & ears on the ground, translating our partner's hardest asks into internal efforts, scoping and driving projects to tackle novel challenges alongside our research and engineering teams. Your findings will guide the future of our product, our models, and our approach.

It will be a lot of fun, a lot of work, and extraordinarily rewarding.

About you

We index on ravenous curiosity, outlier aptitude and collaboration smarts. You operate with urgency, have well-honed communication skills, and probably can't sleep if something isn't right.

We value academic research and drug discovery industry experience in antibody engineering, protein design, and computational methods. We are more than willing to bet on rising stars. Low-ego, high-EQ, and performance under pressure are what we're looking for.

We offer

The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect & promote a culture of high velocity and ownership. We compensate our team accordingly.

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