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Salary
$235k – $260k per year
Location
In office (United States)
Seniority
Architect · 8+ years exp
Visa
No sponsorship (stated in the posting)
Employment
Full-Time

Confirmed on the employer's own hiring board on Oct 25, 2026. First seen by Alion on Jun 18, 2026.

Overview
Company
Impact
Profile match
Compass Pathways is a British biotechnology company headquartered in London that develops psychedelic treatments for mental health conditions, led by COMP360, its investigational synthetic psilocybin therapy for treatment-resistant depression and post-traumatic stress disorder. Founded in 2016 and listed on Nasdaq, it has a US office in New Jersey, holds FDA Breakthrough Therapy designation for COMP360 in treatment-resistant depression and runs the largest classic psychedelic clinical program in that indication. It is building a US commercial team, hiring neuroscience therapeutic sales specialists, site of care account leads, sales operations, commercial strategy and legal staff.
Backed by Aisling Capital

Company introduction:

Compass Pathways plc (Nasdaq: CMPS) is a biotechnology company dedicated to unlocking urgently needed new treatment options in mental health care. 

The Company is headquartered in London, UK, with a U.S. office in New Jersey. We believe mental health patients deserve the possibility of a better future. Our initial focus is developing COMP360 psilocybin, a proprietary, investigational, synthetic psilocybin treatment under evaluation for treatment-resistant depression (TRD) and post-traumatic stress disorder (PTSD). COMP360 is a potentially first-in-class treatment and has Breakthrough Therapy designation from the U.S. Food and Drug Administration (FDA), as well as Innovative Licensing and Access Pathway (ILAP) designation in the UK for TRD. 

We are leading the world’s largest classic psychedelic clinical program in TRD, and building upon that robust foundation, we are executing a late-stage trial evaluating COMP360 for PTSD, another condition with high unmet need. Our goal is to advance treatments that move the field of psychiatry towards treatment options that offer rapid onset and sustained durability with infrequent dosing. - Compass Pathways

Job overview:   

The field-based Health Economics & Outcomes Research (HEOR) Science Liaison is a scientifically trained, field-based expert, that serves as the interface between the company and external healthcare decision makers (HCDMs), including managed care organizations, pharmacy benefit managers, and other health technology assessment bodies.

The HEOR Science Liaison delivers credible, non-promotional scientific information across clinical evidence, real-world evidence (RWE), pharmacoeconomic information, and health outcomes to support informed formulary, coverage, and reimbursement decisions. The role spans the full product lifecycle and is key to demonstrating the value of innovative therapies to payer and access stakeholders.

Location: Remote in the United States.

Reports to: Director, HEOR.

Roles and responsibilities 

(Include but are not limited to): 

External Scientific Engagement

  • Identify, cultivate, and maintain peer-to-peer relationships with key payer thought leaders, medical/pharmacy directors, formulary decision makers, Chief Medical Officers, Chief Pharmacy Officers, and other HCDMs within assigned geography
  • Deliver fair-balanced, scientifically rigorous presentations on clinical trial data, real-world evidence, pharmacoeconomic models, and patient-reported outcomes (PROs)
  • Respond to unsolicited medical information requests from payer and access stakeholders with accurate, compliant, and timely scientific content
  • Attend and represent the organization at managed care, payer, and scientific conferences to maintain awareness of current landscape issues and emerging data

HEOR Evidence Generation & Dissemination

  • Partner with internal HEOR, RWE, and Medical Affairs teams to identify evidence gaps and support the design, execution, and dissemination of field-based observational studies, retrospective analyses, and pharmacoeconomic research
  • Facilitate investigator-initiated and collaborator-initiated research proposals; coordinate with appropriate internal stakeholders for review and approval
  • Support development and communication of health economic models, cost-effectiveness analyses, and budget impact tools for payer audiences
  • Contribute to publications, posters, and abstracts for scientific meetings and peer-reviewed journals

Payer Landscape Intelligence & Insights

  • Gather and synthesize field intelligence on evolving payer policies, formulary decisions, coverage criteria, value-based contracting trends, and competitive landscape dynamics
  • Communicate insights to internal stakeholders including Medical Affairs, Market Access, HEOR, and Commercial teams to inform strategy and evidence planning
  • Monitor and interpret changes in managed care regulations, government payer policy (CMS, Medicare, Medicaid, VA/DoD), and HTA methodologies

Cross-Functional Collaboration & Training

  • Serve as a scientific resource to Market Access Account Directors, Commercial teams, and other field-based colleagues; provide training on disease state, clinical data, and health economics topics
  • Collaborate with Medical Science Liaisons (MSLs), Global Medical Affairs, and HEOR headquarters teams to align field activities with overarching medical strategy
  • Appropriately collaborate with the Market Access team to educate and inform payers about clinical and health economic aspects of Compass Pathways’ investigational and on-market products
  • Participate in advisory board activities, scientific symposia, and payer-focused medical education programs
  • Complete all required training, compliance reporting, and administrative responsibilities in accordance with corporate policy and applicable law
  • Ensure all field activities comply with legal, regulatory, and industry (PhRMA/AMCP) guidelines, with particular attention to controlled-substance and REMS-related communication standards.

Candidate Profile: 

  • Advanced degree (M.D., D.O., Pharm.D. Ph.D.) or MPH/MS in a relevant scientific or health-related discipline (health economics, pharmacoeconomics, epidemiology, health services research, public health, or clinical sciences) required
  • Minimum 8-12+ years pharma/biotech, including 5+ years in field HEOR, Value/Outcomes Liaison, or Market Access roles presenting to and engaging with payer customers, in collaboration with the Market Access function
  • Demonstrated knowledge of health economics methodology, including cost-effectiveness analysis, budget impact modeling, QALYs, systematic reviews, and meta-analyses
  • Strong understanding of the US payer landscape, formulary management, and reimbursement processes
  • Proven ability to translate complex scientific and economic data into clear, compelling narratives for payer and access audiences
  • Valid driver’s license and ability to travel 50-70% of the time by car and air

Compensation Description (annually):

Our compensation package for permanent hires includes base salary, discretionary bonus, and equity, alongside our comprehensive benefits offering.

Please note that the base salary range is a guideline, and individual total compensation will vary based on factors such as qualifications, skill level, competencies, and work location.

Base salary per annum:

$235,000—$260,000 USD

Benefits:

For an overview of our benefits package and compensation information, please visit  "Joins us - Our Benefits ".

These include flexibility & generous time off, parental & reproductive support, health & medical, mental health & wellbeing and Financial health.

Equal opportunities: 

Reasonable accommodation

We are committed to building a workplace where everyone’s wellbeing matters. If you need reasonable accommodation during the interview process to be at your best, please let our recruiting team know. 

UK applicants

We are proud of our commitment to diversity and equality (pursuant to the Equality Act 2010). We do not discriminate based upon race, religion or belief, colour, nationality, ethnic or national origin, gender, pregnancy or maternity, marital or civil partner status, sexual orientation, gender reassignment, age or disability.

US applicants

Compass Pathways is proud to be an equal opportunity employer. All employment decisions are based on business needs, job requirements, and individual qualifications, without regard to race, religion, color, national origin, sex (including pregnancy, childbirth, and related medical conditions), ethnicity, age, disability, sexual orientation, gender identity, gender expression, military service, genetic information, familial or marital status, or any other status, category, or characteristic protected by applicable law.

Sponsorship:

Unfortunately, we cannot sponsor employment visas and can only accept applications if you have employment rights in the country to which you are applying.

Data Privacy:

All data is confidential and protected by all legal and data privacy requirements, please see our recruitment Privacy Notice to learn more about how we process personal data.

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