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Salary
$104k – $122k per year
Location
In office (Cambridge)
Seniority
Principal
Visa
H-1B filings in 12 months: 3
Employment
Full-Time

Confirmed on the employer's own hiring board on Nov 12, 2026. First seen by Alion on Nov 12, 2026. eGenesis scores A on the Alion truth index.

Overview
Company
Impact
Profile match
eGenesis is a biotechnology company developing xenotransplantation products based on molecular and cellular engineering. It hires preclinical and translational research associates, computational biologists, clinical trial managers and farm and animal care technicians. The company is headquartered in Cambridge, Massachusetts, United States.

POSITION SUMMARY

We are seeking a highly motivated Principal Research Associate to join the Analytical Development team. This is an opportunity to develop analytical methods supporting gene-edited xenotransplantation products in a dynamic environment focused on molecular and cellular engineering.

In this role, you will independently develop analytical assays from initial concept and feasibility through optimization, qualification, and transfer. Responsibilities include assessing transgene expression and biological function in genetically modified porcine cells, with a particular emphasis on developing robust, mechanism-relevant potency assays. The successful candidate will be expected to select appropriate assay formats and biological readouts, establish controls, understand critical assay variables, and solve complex development challenges with limited supervision.

The position involves significant hands-on cell culture, including the isolation, growth, and maintenance of porcine primary cells. Methods may include cell-based functional assays, flow cytometry, ELISA, and real-time PCR. This is a full-time, laboratory-based position suited for a proactive, rigorous, collaborative scientist who is comfortable building new methods where established procedures may not yet exist.

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