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Salary
$152k – $215k per year
Location
In office (Alameda)
Seniority
Senior · 5+ years exp
Visa
H-1B filings in 12 months: 33 · green card filings: 10
Employment
Full-Time

Confirmed on the employer's own hiring board on Nov 5, 2026. First seen by Alion on Sep 22, 2026.

Overview
Company
Impact
Profile match
Exelixis is an American oncology-focused biotechnology company headquartered in Alameda, California, that discovers, develops and commercializes small-molecule cancer medicines. Operating in the biotech sector for about 25 years, it built a commercial foundation on its lead cancer product and reinvests that revenue in drug discovery, clinical development and a pipeline of investigational therapies. Its main lines of work and hiring cover medicinal chemistry and research science, vivarium operations, clinical supply and trial management, regulatory affairs, quality assurance, franchise analytics, legal contracts, and IT and AI engineering for enterprise platforms.
Backed by Atlas Venture

SUMMARY/JOB PURPOSE

The Senior Finance Manager - R&D will be responsible for developing financial forecasts, crafting management reports, supporting close cycles, and delivering strategic analyses for the PSC organization. This position serves as the primary finance partner to the Pharmaceutical Operations and Supply Chain (PSC) organization, which comprises all technical operations/CMC activities, including manufacturing, validation, drug product/substance, and testing. This Senior Finance Manager - R&D acts as a key advisor to the Head of PSC and each of the PSC cost center leaders, contributing to the organization's achievement of its targets and ensuring financial discipline in the allocation of resources.

ESSENTIAL DUTIES/RESPONSIBILITIES

  • Partner with PSC functional leaders to drive results that are aligned with corporate targets/objectives
  • Develop bottoms-up PSC financial forecasts and regularly monitor performance against forecasts
  • Own the financial planning process for all CMC groups, including manufacturing, validation, drug substance, drug product, testing, and biologics activities
  • Cultivate discipline and accountability across PSC business teams, ensuring projections align with clinical development timelines
  • Drive continuous improvement and training with PSC business teams to bolster literacy of accrual methodologies and financial targets
  • Support monthly close process; validate PSC accruals in collaboration with accounting team
  • Partner with study delivery leads to develop clinical trial forecasts that accurately reflect study plans and requirements
  • Serve as FP&A point of contact for PSC CAPEX support
  • Assist FP&A clinical accrual team with clinical site accrual model updates
  • Support ad hoc projects as needed
  • Performs other duties as assigned
  • Complies with all policies and standards

SUPERVISORY RESPONSIBILITIES

  • No supervisory responsibilities.

EDUCATION/EXPERIENCE/KNOWLEDGE/SKILLS & ABILITIES

Education

  • BS/BA degree in related discipline and 9 years of related experience; or,
  • MS/MBA/MA degree in related discipline and 7 years of related experience; or,
  • Equivalent combination of education and experience.

Experience

  • CMC / technical operations forecasting experience required
  • Minimum of 5 years of Public Biotech/Pharmaceutical experience
  • Minimum of 5 years in business-partner-facing finance role
  • Experience with financial planning systems required (e.g., Oracle EPBCS, Hyperion, Netsuite, or similar)
  • Demonstrated growth in responsibility in FP&A, corporate finance, accounting, or similar finance function

Knowledge, Skills and Abilities

Required:

  • Strong analytical, strategic, problem solving and organizational skills
  • Exceptional business partnering skills - ability to influence without authority
  • Strong communication (verbal and written) and presentation skills
  • Ability to build strong cross functional relationships within an organization
  • Ability to meet tight deadlines
  • Broad business acumen
  • Advanced knowledge of Excel & and PowerPoint

Travel Requirements

  • 0% Travel not required.

Environmental Requirements:

  • Our office is a modern, open space that foster collaborations and creativity.
  • Teams work closely together, sharing ideas and solutions in a supportive atmosphere.
  • We provide all necessary equipment, including dual monitors and ergonomic chairs, to ensure a comfortable workspace.
Our compensation reflects the cost of labor across several U.S. geographic markets, and we pay differently based on those defined markets. The base pay range for this position is $152,000 - $215,000 annually. The base pay range may take into account the candidate’s geographic region, which will adjust the pay depending on the specific work location. The base pay offered will take into account the candidate’s geographic region, job-related knowledge, skills, experience and internal equity, among other factors.In addition to the base salary, as part of our Total Rewards program, Exelixis offers comprehensive employee benefits package, including a 401k plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Employees are also eligible for a discretionary annual bonus program, or if field sales staff, a sales-based incentive plan. Exelixis also offers employees the opportunity to purchase company stock, and receive long-term incentives, 15 accrued vacation days in their first year, 17 paid holidays including a company-wide winter shutdown in December, and up to 10 sick days throughout the calendar year.

If you have a disability and need an accommodation in relation to the recruiting process, please email us at: [email protected].

WORKING CONDITIONS:

Our office is a modern space that fosters collaboration and creativity. Teams work closely together, sharing ideas and solutions in a supportive atmosphere. We provide all necessary equipment, including dual monitors and ergonomic chairs, to ensure a comfortable workspace.

DISCLAIMER:

The preceding job description has been designed to indicate the general nature and level of work performed by employees within this classification. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities and qualifications required of employees assigned to the job.

We are an Equal Opportunity Employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity, status as a veteran, and basis of disability or any other federal, state or local protected class.

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