2,219,862open jobs
142,787companies
252,288added this week
Browse all
Salary
$190k – $240k per year
Location
In office (Alameda)
Seniority
Architect · 7+ years exp
Visa
H-1B filings in 12 months: 33 · for this role: 4 · green card filings: 10
Employment
Full-Time

Confirmed on the employer's own hiring board on Nov 12, 2026. First seen by Alion on Nov 9, 2026.

Overview
Company
Impact
Profile match
Exelixis is an American oncology-focused biotechnology company headquartered in Alameda, California, that discovers, develops and commercializes small-molecule cancer medicines. Operating in the biotech sector for about 25 years, it built a commercial foundation on its lead cancer product and reinvests that revenue in drug discovery, clinical development and a pipeline of investigational therapies. Its main lines of work and hiring cover medicinal chemistry and research science, vivarium operations, clinical supply and trial management, regulatory affairs, quality assurance, franchise analytics, legal contracts, and IT and AI engineering for enterprise platforms.
Backed by Atlas Venture

SUMMARY/JOB PURPOSE:

The Senior Staff Engineer - Cloud Platform will support the design and creation of cloud-based products and services to meet the technology needs of Exelixis. This position will help define and design our cloud platform, which includes cloud automation tools and standards, CI/CD pipelines, DevOps tooling and AWS account provisioning automation. This position will also work with application support teams to re-define the interface between our cloud platform products and application installation and configuration processes.

ESSENTIAL DUTIES/RESPONSIBILITIES:

Product Strategy & Product Road Map:

  • Develop technical solutions to complex problems which require the regular use of ingenuity and creativity.
  • Understands key business processes and business areas.

Product Development & Delivery:

  • Guides the successful completion of major initiatives or programs and lead mid to large size complex projects.
  • Lead end-to-end development processes, from ideation through CI/CD, security scanning, and production monitoring.
  • Identify and implement improvements to overall processes and development procedures.
  • Develops and applies complex and often long-term strategies on specific projects.
  • Represents the department as the prime technical contact on contracts and projects.
  • Exhibits broad knowledge of state-of-the-art engineering principles and theories.

Stakeholder Management & Cross-Functional Collaboration:

  • Translates overall direction and strategy and communicates across organizational levels and functions.
  • Works on strategic initiatives.
  • Interacts with senior external personnel on significant technical matters often requiring coordination between organizations.

Operational Excellence, Quality & Compliance:

  • Document infrastructure and work instructions for systems and applications, including architecture diagrams, runbooks and code-level commits / READMEs.
  • Lead and own incident response and root cause analysis for high-impact issues.
  • Ensure that completed work delivers long-term value, including the aspects of maintainability, performance and observability.
  • Make decisions regarding access, permissions, and security controls across systems.

Subject Matter Expertise:

  • Serve as the SME for assigned capabilities, providing technical leadership and guidance.
  • Mentor and coach junior engineers, fostering technical growth and best practices.

SUPERVISORY RESPONSIBILITIES:

No supervisory responsibilities.

EDUCATION/EXPERIENCE/KNOWLEDGE & SKILLS:

Education:

  • Master's degree in a relevant field and 7 years of experience; or
  • Bachelor’s degree in a relevant field and 9 years of related experience; or
  • Associate degree and 11 years of experience; or
  • Equivalent combination of education or years of experience
  • Technical certification may be required

Experience:

  • At least 7 years of experience in cloud infrastructure in a highly available and production environment.
  • Experience working in a SOX and FDA regulated environment is a plus.
  • Enterprise Integration: Design, architect, build, test, and support complex enterprise integrations using iPaaS technologies, with strong knowledge of integration architecture, APIs, event-driven patterns, data transformation, security, and error handling.
  • iPaaS Expertise, Required: Significant hands-on experience developing integrations on an enterprise iPaaS platform is required. Experience with SAP Integration Suite is strongly preferred, although experience with other leading iPaaS platforms is acceptable.
  • SAP & S/4HANA Integration: Experience integrating enterprise applications with SAP S/4HANA and other SAP solutions, including APIs, events, and application-to-application integration patterns, is highly preferred.
  • EDI/B2B Integration: Experience designing and implementing EDI and B2B integrations with customers, suppliers, logistics providers, and other external partners is preferred.
  • Full-Stack Development: Strong software engineering background with the ability to design and build modern web applications and APIs. Full-stack development experience with React is preferred, with enterprise integration remaining the primary focus of the role.

Knowledge, Skills and Abilities:

  • Advanced level knowledge of Amazon Web Services (AWS), especially with services related to hosting: EC2, RDS, Systems Manager, IAM, etc.
  • Advanced level knowledge with infrastructure as code (IaC) tools, especially Terraform.
  • Intermediate level knowledge with cloud and infrastructure automation.

Work Environment/Physical Demands:

Our office is a modern, open-plan space that fosters collaboration and creativity. Teams work closely together, sharing ideas and solutions in a supportive atmosphere. We provide all necessary equipment, including dual monitors and ergonomic chairs, to ensure a comfortable workspace.

This position will require minimal travel.

#LI-EZ1

Location: Alameda, CA Range for this position: $190,000 - $239,500 The base pay offered will take into account job-related knowledge, skills, experience and internal equity, among other factors.In addition to the base salary, as part of our Total Rewards program, Exelixis offers comprehensive employee benefits package, including a 401k plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Employees are also eligible for a discretionary annual bonus program, or if field sales staff, a sales-based incentive plan. Exelixis also offers employees the opportunity to purchase company stock, and receive long-term incentives, 15 accrued vacation days in their first year, 17 paid holidays including a company-wide winter shutdown in December, and up to 10 sick days throughout the calendar year.

Exelixis is an Equal Opportunity Employer. We are committed to fostering an inclusive environment where everyone can thrive. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, pregnancy (including lactation, childbirth, or related medical conditions), sexual orientation, gender identity, age (40 and over), national origin or ancestry, citizenship or immigration status, physical or mental disability, genetic information (including testing and characteristics), veteran status, uniformed servicemember status, or any other characteristic protected by applicable federal, state, or local law. We are also committed to providing reasonable accommodations to qualified individuals with disabilities, unless undue hardship and/or a direct threat to the health and/or safety of the individual or others would result.

If you have a disability and need an accommodation in relation to the recruiting process, please email us at: [email protected].

Exelixis is an E-Verify employer.

WORKING CONDITIONS:

Our office is a modern space that fosters collaboration and creativity. Teams work closely together, sharing ideas and solutions in a supportive atmosphere. We provide all necessary equipment, including dual monitors and ergonomic chairs, to ensure a comfortable workspace.

DISCLAIMER:

The preceding job description has been designed to indicate the general nature and level of work performed by employees within this classification. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities and qualifications required of employees assigned to the job.

Free account
Stop reading job ads. Get the ones that fit.
One free account turns this page into a shortlist built around your stack, your level and your pay.
Match on every job. Stack, seniority, pay and location, scored against your profile.
2,219,862 open roles. Read straight off company career pages, refreshed every day.
Unlimited applications. Every one you send is tracked in one place, on-site or on a company board.
3 tailored CVs a month. Rewritten for the exact job you are applying to. Included free.
Create a free account Continue with Google
Free forever. No card. Under a minute.

Your match

How well do you fit this role?
Two answers are enough for a real match. No account needed.
Check my fit
Answers stay in this browser until you create an account.

Recommended for you based on this role

Backend
Remote, many countries
Similar stack
Same company
Alameda
$143k – $173k per year · Hybrid · Full-Time · 8+ years exp · Bachelor's Degree · Roseville
Python
JavaScript
SQL
C#
C#
.NET
AI/ML
AI Agents
Agentic Workflows
DevOps
Rest API
Azure
CI/CD
Docker
Apply
In office · Full-Time · 5+ years exp · Bachelor's Degree · Detroit
Python
JavaScript
TypeScript
C#
C#
.NET
DevOps
Rest API
Azure
AWS
Management
Agile
Apply
$85k – $102k per year · In office · Full-Time · 5+ years exp · Bachelor's Degree · College Park
Java
DevOps
Windows
Unix
Apply
$161k – $224k per year · In office · Top Secret · Full-Time · Torrance
Go
JavaScript
Rust
TypeScript
C++
Databases
MySQL
PostgreSQL
TimescaleDB
InfluxDB
AI/ML
Time Series
Frontend
Angular
React.js
DevOps
Rest API
Terraform
Ansible
GCP
Prometheus
GitLab CI
Azure
CI/CD
Jenkins
AWS
Grafana
Amazon S3
IoT
FreeRTOS
Apply
$94k – $137k per year · Hybrid · Full-Time · 3+ years exp · Chicago
Analytics
Tableau
Management
Confluence
Jira
ServiceNow
Agile
Scrum
ITIL
Apply
Remote (likely EAEU) · Saint Petersburg
Python
C++
Perl
DevOps
Debian
Linux
TCP/IP
Cryptography
OpenSSL
Apply
up to $42k per year · Remote (likely EAEU) · Full-Time · Moscow
Python
TypeScript
Python
SQLAlchemy
FastAPI
Databases
PostgreSQL
ElasticSearch
AI/ML
Claude Code
DevOps
GitLab CI
Docker
Kubernetes
GitLab
Cybersecurity
Keycloak
Authentik
OWASP Top 10
Management
Confluence
Jira
QA
Playwright
Pytest
Apply
$8.3k per year (net) · Remote (likely EAEU) · Internship · Rostov-on-Don
Java
Java
Spring Framework
Hibernate
Databases
MySQL
PostgreSQL
DevOps
Git
Apply
up to $42k per year · Remote (likely EAEU) · Full-Time · Moscow
Python
JavaScript
Java
TypeScript
Python
Django
Java
Spring Boot
Databases
MySQL
PostgreSQL
AI/ML
Claude Code
Frontend
React.js
DevOps
Terraform
Ansible
Helm
GitLab CI
Docker
Kubernetes
GitLab
Management
Confluence
Jira
Apply
Equity · Remote (EU, Europe)
Databases
PostgreSQL
ClickHouse
AI/ML
Model Context Protocol
Prompt Engineering
AI Agents
LLM
RAG
DevOps
Rest API
gRPC
Terraform
GCP
Loki
Prometheus
Azure
CI/CD
GitOps
ArgoCD
AWS
Kubernetes
Grafana
Amazon EKS
Google GKE
Azure AKS
GitHub
GitLab
IAM
Apply
$300k – $380k per year · Hybrid · Nationals only · Full-Time · 8+ years exp · Alameda
Python
C++
AI/ML
Computer Vision
Machine Learning
Robotics
SLAM
Sensor Fusion
Apply
$318k – $402k per year · In office · Full-Time · 8+ years exp · Alameda
DevOps
GCP
Apply
In office · Full-Time · Alameda
Apply
In office · 6+ years exp · Bachelor's Degree · Alameda
Apply
In office · Full-Time · 10+ years exp · Bachelor's Degree · Alameda
Apply
See all jobs
This is one of many
2,219,862 more open roles from verified company boards, updated every day.