1,828,703open jobs
106,110companies
265,886added this week
Browse all
Salary
≈ $79k – $212k per year (Estimated)
Location
In office (Cambridge)
Visa
H-1B filings in 12 months: 10 · green card filings: 2

Confirmed on the employer's own hiring board on Oct 19, 2026. First seen by Alion on Oct 16, 2026. Flagship Pioneering scores A on the Alion truth index.

Overview
Company
Impact
Profile match
Flagship Pioneering is a life sciences venture creation and platform investment firm headquartered in Cambridge, Massachusetts. Founded in 2000 by CEO Noubar Afeyan, the firm operates on a novel institutional innovation model where it acts as a principal founder, funder, and operator of first-in-category biotechnology and sustainability companies.

Flagship Pioneering is a biotechnology company that invents and builds platform companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble capital to allow them to take courageous leaps. Those big leaps in human health and sustainability exponentially accelerate scientific progress in areas ranging from cancer detection and treatment to nature-positive agriculture.  

What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our scientific founders, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and transform for the benefit of people and planet.  

Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. 

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies.

ABOUT THE ROLE

Flagship Pioneering is seeking an Interim HR Manager to provide full-cycle HR support across a portfolio of multiple early-stage life sciences companies during a planned leave of absence. This is a high-autonomy, high-breadth role - you'll be the primary HR resource for companies ranging from 1 to 15 employees, each at a different stage of building out their people infrastructure.

This role is ideal for an experienced HR manager who thrives in ambiguity, can context-switch rapidly across organizations, and knows how to prioritize in environments where everything feels urgent.

Duration: ~5 months  |  Location: On-Site 4 days per week, Cambridge, MA  |  Reports To: Senior HR Business Partner

WHAT YOU'LL DO

Employee Lifecycle & Operations

  •  Deliver day-to-day HR services including onboarding, performance management, employee relations, and offboarding across all portfolio companies
  •  Maintain HR records and ensure data integrity across HRIS and other people systems
  •  Assist with compensation benchmarking, job leveling, and offer structuring as new roles are created

Cross-Functional Collaboration

  •  Align closely with Talent Acquisition, Payroll, Legal, and Learning & Development to maintain consistency across portfolio companies
  •  Ensure all companies remain compliant with applicable federal, state, and local employment laws; partner with outside counsel as needed

Administrative Support

  •  Provide general HR administrative support to the Senior HR Business Partner as needed, including scheduling, document management, tracking action items, and coordinating across portfolio companies

WHAT WE'RE LOOKING FOR

  •  5+ years of HR generalist and/or business partner experience, ideally supporting multiple business units or startup-stage companies simultaneously
  •  Strong working knowledge of multi-state employment law and HR compliance requirements
  •  Prior experience in biotech, life sciences, pharmaceuticals, or fast-growing startup environments
  •  Experience supporting companies in early stages of HR infrastructure build-out (no handbook, no formal processes - you've been there before)
  •  Comfortable operating independently with minimal direction; able to manage competing priorities across organizations
  •  Strong command of confidential matters, data-driven decision-making, and interpersonal communication
  •  SHRM-CP/SCP or PHR/SPHR preferred

WHY THIS ROLE

You'll have real impact across a diverse set of companies during a critical period of growth. No two days look the same, and you'll have the autonomy to make decisions and drive outcomes.

Privacy Notice for Applicants:  When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact [email protected]. 

The salary range for this role is $40 - $100. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Flagship Pioneering currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Flagship Pioneering's good faith estimate as of the date of publication and may be modified in the future.

Privacy Notice for Applicants:  When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact [email protected]. 

Free account
Stop reading job ads. Get the ones that fit.
One free account turns this page into a shortlist built around your stack, your level and your pay.
Match on every job. Stack, seniority, pay and location, scored against your profile.
1,828,703 open roles. Read straight off company career pages, refreshed every day.
Unlimited applications. Every one you send is tracked in one place, on-site or on a company board.
3 tailored CVs a month. Rewritten for the exact job you are applying to. Included free.
Create a free account Continue with Google
Free forever. No card. Under a minute.

Your match

How well do you fit this role?
Two answers are enough for a real match. No account needed.
Check my fit
Answers stay in this browser until you create an account.

Recommended for you based on this role

HR
Similar stack
Same company
Cambridge
$65k – $105k per year • Equity • In office • Full-Time • 2+ years exp • High School Diploma • Aurora
Apply
≈ $58k – $156k per year (Estimated) • Equity • In office • Full-Time • Portland
Apply
$60k – $100k per year • Equity • In office • Full-Time • 2+ years exp • High School Diploma • Norcross
Apply
Truck Builder 7 days ago
≈ $39k – $77k per year (Estimated) • Equity • In office • Full-Time • 1+ year exp • High School Diploma • Aurora
Management
Outlook
Apply
$60k – $70k per year • In office • Part-Time • Kennesaw
Apply
$81k – $94k per year • Hybrid • Full-Time • Hamburg
Cybersecurity
GDPR
Marketing
LinkedIn
Apply
≈ $41k – $93k per year (Estimated) • Hybrid • Full-Time • 8+ years exp • Master's Degree • Bucharest
DevOps
GCP
Azure
AWS
Incident Management
Cybersecurity
ISO 27001
SOC 2
GDPR
Management
Agile
Apply
Data & AI Engineer 10 hours ago
≈ $130k – $286k per year (Estimated) • Remote (United States) • Full-Time • Bachelor's Degree
Python
SQL
Databases
Databricks
Delta Lake
AI/ML
Spark
MLFlow
DevOps
Terraform
GCP
Azure
CI/CD
AWS
Cybersecurity
SOC 2
GDPR
HIPAA
Analytics
ETL/ELT
Management
Agile
Apply
Solution Architect 10 hours ago
≈ $20k – $46k per year (Estimated) • Remote (likely EAEU) • 3+ years exp • PhD • Minsk
AI/ML
AI Agents
DevOps
Azure
CI/CD
AWS
FinOps
Cybersecurity
PCI DSS
GDPR
HIPAA
Management
Agile
Apply
≈ $40k – $104k per year (Estimated) • In office • Bengaluru
Python
Java
Java
Spring Boot
Databases
Apache Kafka
AI/ML
Spark
AI Agents
Flink
Machine Learning
Mobile
Room
DevOps
GCP
CI/CD
Kubernetes
Cybersecurity
GDPR
Apply
$76k – $104k per year • In office • 2+ years exp • Bachelor's Degree • Cambridge
Cybersecurity
GDPR
Management
Outlook
Microsoft Office
Apply
$155k – $190k per year • In office • 5+ years exp • PhD • Cambridge
Cybersecurity
GDPR
Apply
$168k – $259k per year • In office • 5+ years exp • PhD • Cambridge
Python
AI/ML
Fine-tuning
Machine Learning
DevOps
HPC
Cybersecurity
GDPR
Apply
$270k – $320k per year • In office • 15+ years exp • Bachelor's Degree • Cambridge
Cybersecurity
GDPR
Management
SharePoint
Microsoft Office
Apply
Office Manager 3 days ago
$60k – $83k per year • In office • 2+ years exp • Bachelor's Degree • Cambridge
Cybersecurity
GDPR
Management
Google Workspace
Apply
$135k – $140k per year • In office • 3+ years exp • Cambridge
Apply
$264k – $350k per year • Equity • In office • Full-Time • 15+ years exp • Bachelor's Degree • Cambridge
DevOps
AWS
Management
Agile
Apply
$151k – $237k per year • In office • Full-Time • 5+ years exp • Bachelor's Degree • Cambridge
AI/ML
Copilot
DevOps
Azure
Apply
$185k – $250k per year • Equity • In office • Full-Time • 8+ years exp • Cambridge
Management
Agile
Apply
$64k – $72k per year • In office • Contractor • 2+ years exp • Cambridge
Apply
See all jobs
This is one of many
1,828,703 more open roles from verified company boards, updated every day.