2,154,291open jobs
138,636companies
240,301added this week
Browse all
Salary
$142k – $212k per year
Location
In office (San Diego)
Seniority
Architect · 12+ years exp
Visa
H-1B filings in 12 months: 92 · for this role: 28 · green card filings: 41
Employment
Full-Time

Confirmed on the employer's own hiring board on Nov 10, 2026. First seen by Alion on Sep 10, 2026. Illumina scores A on the Alion truth index.

Overview
Company
Impact
Profile match
Illumina is an American company founded in 1998 whose sequencing machines drove the cost of reading a human genome from hundreds of millions of dollars to a few hundred, and it holds the dominant share of the market it largely created. Its business is a classic instruments and consumables model: sequencers are sold once and then consume proprietary reagent kits for years, which is where most of the profit sits. Headquartered in San Diego and listed on Nasdaq, it spent years entangled in the forced divestiture of the cancer test maker Grail and now faces genuine competition from Chinese and startup sequencing platforms for the first time.
What if the work you did every day could impact the lives of people you know? Or all of humanity?At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.

Location

San Diego, CA

Position Summary

Illumina is in search of a Sr Staff Business Systems Analyst to act as a Solution Architect during system design, build, and overall delivery of end-end SAP Transportation Management System implementation, enhancements, and digital transformation initiatives.

Responsibilities

  • Be seen as an SAP TMS expert and able to advise on standard SAP solution design and configuration for specific SAP modules and the impact of the changes on solutions and/or business process
  • Collaborate with Global Process Owners, Global Process Leads, Solution Design Leads and Value Stream Leads process design recommendations, defining end-to-end processes and issue resolutions
  • Identify and implement business process improvements.
  • Collaborate with the global supply chain team and GIS team to evaluate support requests.
  • Gather and analyze requirements to determine the best solution.
  • Provide routine updates to the global team regarding upcoming enhancements, bug fixes, and improvements to the business system to support regulatory audits, efficiency improvements, and additional functionality.
  • Keep up to date with the latest SAP technology, especially within S/4 HANA TMS and EWM.
  • Collaborate with Global Process Owners, Global Process Leads, Solution Design Leads and Value Stream Leads on issue resolution and process design recommendations.
  • Lead and influence cross-functional teams to develop improved processes and communication in support of business initiatives, also with the ability to deliver high-quality outcomes, particularly under tight timelines.
  • Escalate appropriate decision-making requirements or process "choice points" to Global Process Owner and GIS Leads.
  • Ability to articulate or demonstrate SAP TMS solutions and deliver high-quality outcomes, particularly under tight timelines.

Requirements

  • 12+ Years of SAP experience with extensive SAP TMS implementation and solution architect roles.
  • Experience functional lead with demonstrated capability to work cross teams.
  • Experience in implementation of SAP TMS with various deployment options preferably TMS on S/4 HANA.
  • Strong exposure of SAP TMS, SCT Software Carrier Integration, TMS Integration with SAP EWM, SAP GTS, SAP EHS modules.
  • Experience in creation of Transportation Management specific Master Data i.e. Routes, Transportation network, Mode, Freight Agreement, Rate Table, Trade Compliance Check etc. Must have sound knowledge and experience in configuring/modifying Post Processing Framework in SAP TMS. Along with a strong expertise in setting up the system integration between SAP TMS with SAP EWM, ECC, GTS on S/4 HANA.
  • Proficient experience in interface development (RFC/ALE/IDoc/Web Services).
  • Extensive experience in analysis, design, development, testing, implementation, and documentation.
  • Knowledge about system enhancements and configuration with IT leadership experience with SAP TMS projects.
  • Strong influencing, facilitating, and consulting skills in working with stakeholders at all levels in the organization and across departments.
  • Consulting background is a plus.
  • Typically requires a minimum of 12 years of related experience with a Bachelor’s degree.
The estimated base salary range for the Sr SAP TMS Solution Architect role based in the United States of America is: $141,600 - $212,400. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. The range reflects long-term growth in the role; therefore, most candidates are hired between the minimum and middle of the range. Placement depends on experience, skills, location, and internal equity. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.

We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact [email protected]. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf. The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants.

Free account
Stop reading job ads. Get the ones that fit.
One free account turns this page into a shortlist built around your stack, your level and your pay.
Match on every job. Stack, seniority, pay and location, scored against your profile.
2,154,291 open roles. Read straight off company career pages, refreshed every day.
Unlimited applications. Every one you send is tracked in one place, on-site or on a company board.
3 tailored CVs a month. Rewritten for the exact job you are applying to. Included free.
Create a free account Continue with Google
Free forever. No card. Under a minute.

Recommended for you based on this role

Enterprise Apps
Remote, many countries
Similar stack
Same company
San Diego
$140k – $160k per year · In office · 1+ year exp · United States
AI/ML
AI Agents
Management
ServiceNow
Agile
Scrum
ITSM
Apply
Hybrid · TS/SCI · 5+ years exp · Bachelor's Degree · Chantilly
JavaScript
PHP
Kotlin
TypeScript
SQL
C#
Kotlin
Glide
C#
.NET
Frontend
Angular
JQuery
DevOps
Rest API
Configuration Management
SOAP
Cybersecurity
Active Directory
LDAP
Management
ServiceNow
Agile
Scrum
UML
ITSM
Apply
Hybrid · 8+ years exp · High School Diploma · Dallas
AI/ML
Machine Learning
Apply
In office · Full-Time · United States
Databases
MySQL
Oracle
AI/ML
Machine Learning
DevOps
Rest API
Azure DevOps
Azure
Management
Agile
Apply
Hybrid · Full-Time · 5+ years exp · Hartford
Apex
Apex
Lightning Web Components
Copado
Aura Components
AI/ML
Agentforce
DevOps
CI/CD
GitHub
Management
Agile
Apply
$17k – $29k per year (net) · Remote (EAEU) · Full-Time · Krasnodar
1C
Apply
Remote (likely EAEU) · Novosibirsk
1C
Databases
MS SQL
Apply
Remote (EAEU) · Moscow
PHP
1C
PHP
Magento
Management
BPMN
Apply
Remote (EAEU) · Moscow
1C
Apply
Remote (EAEU) · 3+ years exp · Moscow
SQL
1C
DevOps
Git
Management
Bitrix24
Apply
≈ $31k – $84k per year (Estimated) · Remote (Mexico) · Full-Time · 5+ years exp · Bachelor's Degree · Mexico
JavaScript
Apex
Apex
Lightning Web Components
Salesforce CLI
AI/ML
Cursor
Claude
ChatGPT
Model Context Protocol
Prompt Engineering
AI Agents
Agentforce
DevOps
Rest API
CI/CD
Git
GitHub
SOAP
Cybersecurity
HIPAA
Management
Agile
Scrum
Apply
≈ $36k – $82k per year (Estimated) · Remote (Mexico) · Full-Time · 5+ years exp · Bachelor's Degree · Mexico
Apex
AI/ML
AI Agents
Agentforce
Human-in-the-Loop
LLM Guardrails
DevOps
Rest API
SOAP
Cybersecurity
HIPAA
Management
Confluence
Agile
Scrum
Apply
≈ $43k – $109k per year (Estimated) · Remote (Mexico) · Full-Time · 8+ years exp · Bachelor's Degree · Mexico
JavaScript
Apex
Apex
Lightning Web Components
Salesforce CLI
AI/ML
Cursor
Claude
ChatGPT
Model Context Protocol
Prompt Engineering
AI Agents
Agentforce
Frontend
Web Components
DevOps
Rest API
CI/CD
Git
GitHub
SOAP
Cybersecurity
HIPAA
Management
Agile
Scrum
Apply
≈ $120k – $243k per year (Estimated) · In office · Full-Time · 12+ years exp · Bachelor's Degree · San Diego
Python
JavaScript
TypeScript
SQL
C#
Databases
Databricks
Apache Kafka
AI/ML
Copilot
Cursor
LangGraph
LangChain
Claude
Claude Code
Model Context Protocol
MLFlow
dbt
AI Agents
Arize Phoenix
DeepEval
LangSmith
Promptfoo
Ragas
AWS Bedrock
Great Expectations
CrewAI
LLM
RAG
Hallucination
Synthetic Data
Braintrust
OpenAI Codex
OpenAI Agents SDK
AWS Bedrock AgentCore
A2A
Human-in-the-Loop
Structured Outputs
Context Engineering
Red Teaming
LLM Guardrails
EU AI Act
NIST AI RMF
Computer Use
Browser Agents
Copilot Studio
Machine Learning
Frontend
GraphQL
Mobile
JUnit
DevOps
gRPC
Splunk
Terraform
Azure DevOps
GitHub Actions
OpenTelemetry
Datadog
Azure
CI/CD
Jenkins
AWS
Docker
Kubernetes
Grafana
Trunk-Based Development
Chaos Engineering
Self-Healing
Amazon EKS
AWS Lambda
SLI/SLO/SLA
GitLab
Amazon ECS
Cybersecurity
Burp Suite
Snyk
OWASP ZAP
Checkmarx
OWASP Top 10
GDPR
HIPAA
Shift-Left Security
SBOM
Management
Jira
ServiceNow
QA
TestNG
Selenium
JMeter
Cypress
Playwright
Gatling
Appium
Postman
WebDriverIO
Rest-Assured
Pytest
Pact
k6
Applitools
MedTech
ISO 13485
IEC 62304
21 CFR Part 11
Apply
$93k – $139k per year · In office · Full-Time · Bachelor's Degree · Cambridge
DevOps
Linux
Management
Confluence
Jira
Life Sciences
Next-Generation Sequencing
Apply
≈ $81k – $155k per year (Estimated) · In office · Full-Time · Bachelor's Degree · Minneapolis · San Diego
Python
SQL
AI/ML
Machine Learning
Analytics
A/B Testing
Microsoft Excel
Apply
$95k – $136k per year · In office · Secret · Full-Time · Bachelor's Degree · San Diego
DevOps
Splunk
VMWare
GitHub
GitLab
Linux
Windows
Cybersecurity
SIEM
Apply
$120k – $150k per year · In office · Secret · Full-Time · Bachelor's Degree · San Diego
DevOps
Splunk
VMWare
GitHub
GitLab
Linux
Windows
Cybersecurity
SIEM
Apply
1778 - Web Developer 4 hours ago
$90k – $120k per year · Remote (United States) · Secret · Full-Time · Bachelor's Degree · San Diego
Python
JavaScript
TypeScript
SQL
Python
Flask
Databases
PostgreSQL
Frontend
React.js
Recharts
DevOps
CI/CD
Windows Server
Docker
Nginx
Cybersecurity
Keycloak
Apply
$110k – $135k per year · In office · Secret · Full-Time · Associate's Degree · San Diego
DevOps
Linux
Windows
TCP/IP
Management
Service Desk
Apply
See all jobs
This is one of many
2,154,291 more open roles from verified company boards, updated every day.