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Salary
$148k – $240k per year
Location
In office (Cambridge, San Francisco)
Seniority
Middle · 4+ years exp
Visa
H-1B filings in 12 months: 29 · for this role: 9

Confirmed on the employer's own hiring board on Nov 10, 2026. First seen by Alion on Nov 10, 2026. Lila Sciences scores A on the Alion truth index.

Overview
Company
Impact
Profile match
Lila Sciences is an American company launched publicly in 2025 out of Flagship Pioneering with the aim of building what it calls scientific superintelligence: artificial intelligence systems that generate hypotheses and then test them in the company's own automated laboratories. Its distinguishing feature is the closed loop between model and experiment, since most scientific machine learning is limited by the fact that the data it needs has never been generated. Headquartered in Cambridge, Massachusetts and funded at an unusually large scale for a company at this stage, it is working across life sciences and materials chemistry rather than committing to a single field.

Your Impact at LILA

Lila is building a platform where AI and automation co-evolve to accelerate scientific discovery Our AI Research team is looking to hire a ML Research Engineer to maximize iteration speed for mid- and post-training runs on 1T+ parameter LLMs using the latest NVIDIA chips. This involves not only maximizing GPU utilization on an individual training run but also making these optimizations maintainable, reusable, and adaptable so that the rest of the research team always knows how to confidently use the latest optimized stack.

What You'll Be Building

  • GPU compute performance: profiling, kernel development, long-context handling, memory footprint optimization
  • GPU cluster performance: collective/MoE framework optimization, comm/compute overlap, RDMA/IB/EFA usage, P/D disaggregation
  • Big data handling: manage mid-training scale data across storage, streaming, tokenization, and processing
  • RL pipeline: optimize the async RL cycle, including environment/sandbox interfacing, long rollout handling, large token metadata (such as router replay), and weight sync
  • Setting the performance standard: make sure optimized configurations are tested, accessible, and adaptable to research tasks so that the whole team can work at maximum velocity
  • Establishing the Pareto frontier: communicate with researchers about throughput/accuracy tradeoffs (e.g. lower-precision compute, higher async staleness) to establish optimal points

What You'll Need to Succeed

  • BS/MS in Computer Science or a related quantitative field and 4+ years working as a software engineer or machine learning engineer, or PhD in a relevant research area and 1+ years work experience.
  • Experience with LLM inference libraries such as vLLM and training libraries such as Megatron, including usage and throughput optimization.
  • Experience running LLM inference and/or training at scale across multi-node GPU clusters.
  • Familiarity with core concepts in reinforcement learning.
  • Proven track record of software engineering excellence - clean APIs, well-tested code, thoughtful abstractions.
  • Hands-on experience supporting and maintaining production libraries used by other engineers and researchers.
  • Strong CI/CD skills - experience designing integration test suites, build pipelines, and automated quality gates for multi-package ecosystems.
  • A passion for agentic systems and awareness of cutting-edge approaches in LLM tool use and autonomy.

Bonus Points For

  • Experience working with kernel DSLs and frameworks like CUDA, CuTe, CuTile, Triton, etc.
  • Experience with GPU networking frameworks like NCCL and NIXL, as well as fabrics like NVLink, IB, and EFA.
  • Experience with distributed systems or compute frameworks (Ray, Flyte, Airflow, or similar).
  • Familiarity with containerized compute backends (Docker, Modal) and sandbox orchestration.
  • Experience with Ray actors, Ray Serve, or similar actor-model frameworks.

Compensation

We offer competitive base compensation with bonus potential and generous early-stage equity. Your final offer will reflect your background, expertise, and expected impact.

U.S. Benefits. Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program.

International Benefits. Full-time employees outside the U.S. receive a comprehensive benefits program tailored to their region. USD salary ranges apply only to U.S.-based positions; international salaries are set to local market.

Expected Base Salary Range

$148,000—$240,000 USD

About LILA

Lila Sciences is building Scientific Superintelligence™ to solve humankind's greatest challenges. We believe science is the most inspiring frontier for AI. Rather than hard-coding expert knowledge into tools, LILA builds systems that can learn for themselves.

LILA combines advanced AI models with proprietary AI Science Factory™ instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy. Learn more at www.lila.ai.

Guided by our core values of truth, trust, curiosity, grit, and velocity, we move with startup speed while tackling problems of historic importance. If this sounds like an environment you'd love to work in, even if you don't meet every qualification listed above, we encourage you to apply.

We’re All In

Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy.

A Note to Agencies

Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto.

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