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Location
Remote/Hybrid (Prague, Czech Republic)
Seniority
Staff · 4+ years exp
Employment
Full-Time
Overview
Company
Impact
Profile match
MSD (Merck & Co., Inc. on NYSE: MRK) is a global research-intensive biopharmaceutical leader headquartered in Rahway, New Jersey. Founded in 1891 as the American affiliate of the original German Merck family enterprise, the company operates as MSD (Merck Sharp & Dohme) across all international markets outside the United States and Canada.

Job Description

We run the enterprise SaaS platforms, APIs, and data integrations that our research organisation depends on every day. You will be the technical owner of one of them: the Signals Research Suite - the electronic lab notebook platform used by scientists across several divisions worldwide.

This is a hands-on configuration, integration, and platform engineering role, not a ticket queue. You will own the technical roadmap, run the release pipeline, drive the vendor feature backlog, automate the manual work away, and decide where the platform goes next.

Our platform happens to serve laboratory and experiment-management workflows, so you will learn that domain here - and you will learn Signals itself here. We do not expect you to arrive with either. What we do expect is that you have owned a production platform before and know how to make one better.

Reports to the Product Technical Lead.

What You Will Do

Own the platform

  • Act as technical owner for the Signals Research Suite and the integrations around it

  • Own the configuration, customisation, and development of the suite's modules to meet evolving research and business needs

  • Translate scientific workflow requirements into platform configuration (templates, experiments, workflows, ADTs) and into integrations with other systems

  • Own and prioritise the enhancement backlog, and contribute to the target-state architecture and technical roadmap for the platform

Run releases and production

  • Manage the full SDLC: requirement gathering and analysis, solution design and configuration, development and scripting, collaboration with testing and UAT teams, deployment via the Configuration Transfer Tool or equivalent, production release, and hypercare

  • Lead investigation and resolution of production incidents across application, API, data, identity, and network layers

  • Drive structured root-cause analysis and corrective actions to closure; improve monitoring, alerting, runbooks, and operational metrics so the next incident is shorter - or does not happen

  • Apply ITSM practices across Incident, Request, Problem, Change, Knowledge, and Release Management

Engineer and integrate

  • Build and maintain integrations between Signals, internal enterprise services, SaaS and cloud applications, and legacy systems, using APIs and middleware

  • Debug data-consistency and integration failures across APIs, event flows, and identity boundaries

  • Use cloud services and enterprise networking knowledge to diagnose and harden platform reliability

  • Support deployments, go-live readiness, rollback planning, and post-deployment stabilisation

Automate and use AI well

  • Automate repetitive operational work - triage, configuration comparison, checks, reporting, provisioning - with scripting and approved tooling

  • Drive AI initiatives that enhance scientific workflows for business users

  • Build internal AI-powered tools (e.g. a technical RAG chatbot) that accelerate team onboarding, troubleshooting, and self-service how-to guidance

  • Use AI-assisted tooling for log analysis, incident triage, investigation, and knowledge capture - and validate its output against real platform evidence before acting on it

Set technical direction

  • Serve as technical liaison with Revvity (the vendor) for escalations, defects, feature requests, enhancements, upgrades, and release coordination

  • Prioritise technical work with the Product Owner, and communicate risk, impact, and options to technical and non-technical audiences alike

  • Collaborate with cross-functional teams including Product Owner, Product Technical Lead, Quality Unit, infrastructure, and support

  • Mentor less experienced engineers and contribute to engineering standards and documentation

  • Work in a global, distributed Agile team following product model practices

Work in a regulated environment

  • Follow established validation, change-control, and documentation practices - our platforms are audit-sensitive, and we will train you on what that means in practice

  • Document configurations, processes, and troubleshooting guides to support knowledge sharing and compliance requirements

  • Identify security, access, and data-protection risks early and bring in security and architecture partners

What You Bring

  • 4+ years engineering, operating, configuring, or owning production software platforms, SaaS solutions, or enterprise systems

  • Real production incident experience: you have been on the sharp end of an outage, led the investigation, and closed the loop afterwards

  • Strong understanding of the complete SDLC, from requirements through production release and hypercare

  • Solid debugging skills across the stack - application, API, data, identity, and network - with a structured approach to root-cause analysis

  • Working knowledge of a major cloud platform (AWS, Azure, or GCP) and of enterprise networking fundamentals (DNS, TLS, firewalls, proxies, connectivity patterns)

  • Scripting or development ability (Python or similar) for automation, and working knowledge of API and integration patterns, including RESTful services

  • Practical use of AI-assisted tools in engineering or operations work, with sound judgement about their output

  • Self-driven and proactive: demonstrated ability to identify opportunities, propose solutions, and execute independently rather than waiting to be asked

  • Clear written and spoken English, and the ability to work with distributed teams across Europe, the US, and India

  • Bachelor's degree in Computer Science, Engineering, Information Systems, or a life sciences field (biology, chemistry, biotechnology, bioinformatics, biomedical engineering, or similar) - or equivalent practical experience. We welcome scientists who moved into engineering

Nice to Have (Not Required)

We will teach you the platform and the domain. Any of the following is a bonus, none is a filter:

  • Experience with an ELN or LIMS platform, and in particular the Signals One Research Suite and its modules (Notebook, VitroVivo, Inventa, CD, Synergy) or the Signals Notebook REST API

  • Other scientific informatics platforms - LIMS, ELN, sample management - or specific products such as Benchling or ZONTAL

  • Familiarity with scientific data standards (SDF, HELM, chemical structures) or with laboratory workflows such as stoichiometry, assay data, or sample management

  • Observability tooling (Dynatrace, Grafana, Datadog, Splunk, CloudWatch or similar)

  • Infrastructure as code, CI/CD pipelines (GitHub, GitHub Actions), or containers

  • Additional languages and libraries: SQL, C#, PowerShell, Bash, Pandas, Streamlit

  • Experience in a regulated, GxP, or otherwise audit-sensitive environment, including 21 CFR Part 11 / Annex 11

  • Experience with AI/LLM technologies, RAG architectures, or building AI-powered internal tools

  • Experience with Agile/Scrum delivery; ITIL v4 Foundation, Six Sigma Green Belt, or similar certification

  • Life sciences, pharma, research, or manufacturing IT background

  • Advanced degree

What Success Looks Like

In the first 6 months you will:

  • Co-deliver 2 Signals software releases to production alongside the existing team

  • Map current configuration, validation, and deployment processes end to end and identify improvement opportunities across them

  • Own and prioritise the Signals enhancement backlog, aligning vendor feature requests with business needs and release timelines

  • Establish yourself as the primary technical liaison with Revvity for feature coordination, escalations, and release planning

In the first 12 months you will:

  • Deliver Signals software releases to production independently

  • Drive 2-3 vendor feature enhancements from requirement through production release, coordinating across Revvity, QA, and business stakeholders

  • Implement automated configuration promotion, reducing manual effort and deployment risk

  • Build and maintain a living enhancement roadmap that gives the Product Technical Lead and Product Owner clear visibility into pipeline status

  • Establish reusable automation (scripts, pipelines, dashboards) that reduces repetitive operational work across the team

  • Deliver an AI-powered knowledge tool (e.g. a chatbot) that enables team self-service for technical how-to questions

Why This Role

  • End-to-end ownership of a platform that directly enables drug discovery and development

  • A technical practice you get to shape, not inherit fully formed

  • Genuine mandate to automate and to apply AI tooling to platform and operations work

  • Prague-based team working closely with US and India engineering

What We Offer

  • Exciting work in a great team, global projects, international environment

  • Opportunity to learn and grow professionally within the company globally

  • Pension and health (Canadian Medical) contributions

  • Internal reward system plus referral program

  • 5 weeks annual leave, 5 sick days, 15 days of certified sick leave paid above statutory requirements annually, 40 paid hours annually for volunteering activities, 12 weeks of parental contribution

  • Cafeteria for tax free benefits according to your choice (meal vouchers, sport, culture, health, travel, etc.), Multisport card, Vodafone, Raiffeisen Bank and Foodora discount programs

  • Up-to-date laptop and iPhone, parking in the garage, showers, refreshments

  • Competitive salary, incentive pay, and many more

Ready to take up the challenge? Apply now!

Know anybody who might be interested? Refer this job!

The date shown below is the earliest possible closing date for this posting. However, we sometimes extend the job posting period as needed, so please feel free to apply anytime you see the "Apply " button available. You may also reach out to the recruiter directly via https://www.linkedin.com/in/badumtss/

Required Skills:

Artificial Intelligence (AI), Cloud Computing, IT Networking, Production Troubleshooting, RESTful APIs, Scripting, Software as a Service (SaaS), Software Development Life Cycle (SDLC), Technical Leadership

Preferred Skills:

CI/CD, Electronic Lab Notebook (ELN), GxPs, Laboratory Information Management System (LIMS), Pharmaceutical Industry, Scrum (Agile)

Current Employees apply HERE

Current Contingent Workers apply HERE

Search Firm Representatives Please Read Carefully

Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:

Regular

Relocation:

No relocation

VISA Sponsorship:

Yes

Travel Requirements:

10%

Flexible Work Arrangements:

Hybrid

Shift:

Not Indicated

Valid Driving License:

No

Hazardous Material(s):

N/A

Job Posting End Date:

09/1/2026

*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

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