685,990open jobs
39,767companies
96,605added this week
Browse all
Salary
$170k – $256k per year
Location
In office (Menlo Park)
Seniority
Staff · 10+ years exp
Employment
Full-Time
Overview
Company
Impact
Profile match
PacBio develops long-read DNA sequencing instruments and consumables. Its HiFi technology produces highly accurate reads that resolve complex genomic regions. Research and clinical laboratories use the platform for genome assembly and variant discovery.

Staff Engineer, Software (Deployment)

PacBio (NASDAQ: PACB) is a premier life science technology company that designs, develops, and manufactures advanced sequencing solutions to help scientists and clinical researchers resolve genetically complex problems. Our mission is to enable the promise of genomics to better human health. Genomics is core to all biological processes, and our advanced genomics tools provide scientists and clinical researchers the insights to better understand biology and health. We are now entering the century of biology and genomics is at the heart of the next revolution. Become part of the new paradigm in gene sequencing and help shape the future of genomic study by joining the PacBio team.

Position Summary:

PacBio’s sequencing instruments are critical to sequencing labs around the world. As a Staff Deployment Engineer, you will work cross-functionally to design, develop, and deploy the compute platforms integrated into our sequencing appliances, our customers’ data centers, and the cloud. You will be expected to set technical direction rather than receive it: to decide what our deployment and platform architectures should look like several years out, build the pieces that do not exist yet, and deliver a product that satisfies CLIA labs and other regulated customers.

Responsibilities:

  • Cloud deployment. Bring core data analysis pipelines to the cloud to offer flexible, on-demand compute capacity for our customers. Provide a secure, reliable, and transparent alternative to on-prem compute. Define and implement the deployment model for cloud-hosted services, including infrastructure as code, environment promotion, secrets management, and delivery pipelines, and establish the patterns other teams will adopt.
  • Build and release pipelines. Consolidate build infrastructure onto a single CI/CD platform, moving builds into containers so they are reproducible and independent of hand-maintained agents. Rationalize dependency management, proselytize statelessness and immutability, and instrument deployment pipelines for predictability and uptime. Develop and implement traceability and retention policies for product lifecycle management.
  • Image architecture and hardware integration. Own image architecture jointly with instrument engineering: composition, maintainability, and performance across node roles and hardware variants. You will build the images themselves with curated package sets, PacBio software, purposeful partition layouts, and the driver, device, and firmware integration each variant requires. This includes virtual machines in production and virtualized server equivalents used for development and test. Support custom hardware interfaces, robotics packages, and low-latency user interfaces.
  • Infrastructure and Configuration as code. Replace bespoke scripting and image-baked state with declarative, reviewable configuration for instruments, build infrastructure, and laboratory systems.
  • Supply-chain integrity and security posture. Establish the assurance capability the product needs: artifact and image signing, verified boot, automated software bill of materials generation, continuous vulnerability ingestion and triage against a defined patch cadence, and a documented hardening baseline.
  • Cross-functional and regulatory execution. Partner with Quality, Regulatory, Manufacturing, IT, and Field Service to make deployment auditable and predictable: traceability from commit to shipped artifact, change control and release documentation, and validated builds delivered to manufacturing on schedule.
  • Technical leadership and resilience. Set engineering standards, review designs and code, and mentor engineers across the organization. Document and de-risk the systems that currently rely on individual knowledge.

Required Qualifications:

  • 10+ years of professional experience in systems, platform, release, or deployment engineering, or a Master’s degree in computer science, computer engineering, or a related discipline plus 8+ years of such experience.
  • Demonstrated experience delivering Linux-based systems on appliance, instrument, or other purpose-built hardware into customer or field environments.
  • Fluency in Python and shell, sufficient to build and maintain production automation that others depend on.
  • Deep, hands-on Linux systems expertise: boot chain, systemd, filesystems and partitioning, packaging, and kernel or driver integration.
  • Experience designing and operating automated, reproducible image build pipelines, with a clear point of view on what makes a build trustworthy.
  • Experience delivering software under formal change control in a regulated or otherwise high-consequence setting, where releases must be auditable and any prior version reproducible on demand.
  • Strong hands-on ownership of CI/CD systems at scale, including pipeline-as-code, containerized builds, build agent fleet management, and infrastructure as code.
  • Production experience deploying cloud services for customer use with at least one major cloud platform (AWS, Azure, or GCP).
  • A track record of setting technical direction for a platform and driving it to completion across multiple teams, including the parts that require persuasion rather than authority.
  • Excellent interpersonal, written, and verbal communication skills.

Preferred Experience:

  • Supply-chain security experience: code and artifact signing, UEFI Secure Boot, dm-verity or equivalent integrity measures, SBOM generation, and software composition analysis tooling.
  • Familiarity with hardening baselines and audit tooling such as CIS Benchmarks, STIG, SCAP, or SELinux policy work.
  • Experience with modern image build tooling such as mkosi, Packer, Yocto, or Buildroot, and with immutable or A/B-updated operating systems.
  • Configuration management and infrastructure-as-code experience with tools such as Ansible, Terraform, or Salt.
  • Experience owning on-premises development infrastructure systems such as Bitbucket, Jenkins, and Artifactory as an end-to-end administrator and architect, not only as a consumer.
  • Experience building or operating an observability stack (for example Prometheus, Grafana, Loki, and Alertmanager).
  • Experience managing secure remote access management systems (for example Tailscale or SecureLink).
  • Experience with on-premises virtualization at scale, such as Proxmox VE or VMware vSphere.
  • Experience mentoring senior engineers or acting as a technical lead without direct reports.

Candidates must have current authorization to work in the United States without the need for present or future sponsorship.

You may be required from time to time to visit and work at PacBio locations and for such times as the Company considers necessary for the proper performance of your duties.

All listed tasks and responsibilities are deemed as essential functions to this position; however, business conditions may require reasonable accommodations for additional tasks and responsibilities.

All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, national origin, protected veteran status, or on the basis of disability, gender identity, and sexual orientation.

Salary Range:

$170,400.00 - $255,600.00

To all Staffing and Recruiting Agencies: Our Careers Site is only for individuals seeking a job at PacBio. Staffing and recruiting agencies and individuals being represented by an agency are not authorized to use this site or to submit profiles, applications or resumes, and any such submissions will be considered unsolicited. PacBio does not accept unsolicited resumes or applications from agencies. Please do not forward resumes to our jobs alias, PacBio employees or any other company location. PacBio is not responsible for any fees related to unsolicited resumes/applications.

All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, national origin, protected veteran status, or on the basis of disability, gender identity, and sexual orientation.

If you are an individual with a disability and require a reasonable accommodation to complete any part of the application process, or are limited in the ability or unable to access or use this online application process and need an alternative method for applying, you may contact us at 650-521-8000, or [email protected] for assistance.

Visit our following pages for more information on:

Free account
Stop reading job ads. Get the ones that fit.
One free account turns this page into a shortlist built around your stack, your level and your pay.
Match on every job. Stack, seniority, pay and location, scored against your profile.
685,990 open roles. Read straight off company career pages, refreshed every day.
Unlimited applications. Every one you send is tracked in one place, on-site or on a company board.
3 tailored CVs a month. Rewritten for the exact job you are applying to. Included free.
Create a free account Continue with Google
Free forever. No card. Under a minute.

Your match

How well do you fit this role?
Two answers are enough for a real match. No account needed.
Check my fit
Answers stay in this browser until you create an account.

Recommended for you based on this role

Similar stack
Same company
Menlo Park
$110k – $125k per year • In office • 5+ years exp • Master's Degree
Databases
PostgreSQL
Weaviate
pgvector
Pinecone
Qdrant
AI/ML
Embeddings
LLM
Semantic Search
Anomaly Detection
Semantic Search
DevOps
GCP
Azure
AWS
Cybersecurity
ISO 27001
SOC 2
Analytics
ETL/ELT
Apply
$130k per year • Remote/Hybrid • TS/SCI • 2+ years exp • Bachelor's Degree
Python
JavaScript
Java
TypeScript
Java
Spring Boot
Databases
ElasticSearch
Frontend
Vue.js
Angular
React.js
DevOps
Terraform
Ansible
GitLab CI
CI/CD
Git
AWS
Docker
Kubernetes
Analytics
Apache NiFi
Apply
$130k per year • In office • TS/SCI • 3+ years exp • Bachelor's Degree
Python
JavaScript
Java
PHP
C++
Node JS
Java
Spring Boot
Quarkus
Apache Tomcat
Databases
ElasticSearch
Apache Solr
DevOps
AWS
Management
Confluence
Agile
Apply
In office
AI/ML
LoRA
Fine-tuning
Quantization
Knowledge Distillation
ONNX
PEFT
QLoRA
Transformers
Hugging Face
Model Distillation
DevOps
CI/CD
Apply
$143k – $326k per year (Estimated) • In office • Full-Time • 2+ years exp • San Francisco
Python
AI/ML
LLM
Synthetic Data
Apply
$196k – $294k per year • Remote/Hybrid • Full-Time • 11+ years exp • Bachelor's Degree • Menlo Park
Robotics
EtherCAT
Apply
$148k – $222k per year • Remote/Hybrid • Full-Time • Menlo Park
DevOps
CI/CD
HPC
Cybersecurity
Zero Trust
Apply
$148k – $222k per year • Remote/Hybrid • Full-Time • Menlo Park
Python
PowerShell
Bash
DevOps
CI/CD
GitOps
Kubernetes
Platform Engineering
HPC
Cybersecurity
ISO 27001
HIPAA
Apply
$107k – $161k per year • In office • Full-Time • 5+ years exp • Raleigh
Apply
$96k – $187k per year (Estimated) • Remote/Hybrid • Full-Time • 4+ years exp • Bachelor's Degree • Menlo Park
Analytics
Microsoft Excel
Apply
$166k – $238k per year • Remote/Hybrid • Full-Time • 7+ years exp • Bachelor's Degree • Menlo Park • Bellevue
Go
Databases
Snowflake
AI/ML
AI Agents
Streamlit
DevOps
CI/CD
Platform Engineering
Management
Linear
Jira
Apply
$180k – $220k per year • In office • Full-Time • 4+ years exp • Bachelor's Degree • Menlo Park
SQL
AI/ML
AI Agents
Marketing
Salesforce
Google Ads
GA4
LinkedIn
Apply
$150k – $200k per year • In office • Full-Time • 2+ years exp • Bachelor's Degree • Menlo Park
SQL
Databases
Snowflake
Databricks
ClickHouse
Trino
StarRocks
AI/ML
AI Agents
Apply
$150k – $200k per year • In office • Full-Time • 5+ years exp • Bachelor's Degree • Menlo Park
Databases
StarRocks
AI/ML
AI Agents
DevOps
AWS
Game Dev
Bevy
Marketing
Salesforce
HubSpot
Apply
Director, FP&A 1 day ago
$216k – $298k per year • Equity • In office • 10+ years exp • Master's Degree • Menlo Park
Apply
See all jobs
This is one of many
685,990 more open roles from verified company boards, updated every day.