Upstream Manufacturing Associate II
Confirmed on the employer's own hiring board on Nov 9, 2026. First seen by Alion on Nov 4, 2026. Planet Pharma scores B on the Alion truth index.
Pay range: 25-35/hr
*depending on experience
Position Overview
The Upstream Manufacturing Associate II independently executes upstream manufacturing operations in a cGMP cleanroom environment. This role requires technical expertise in mammalian cell culture, bioreactor operations, harvest processing, and in-process testing while serving as a mentor to junior associates and supporting process improvements.
Key Responsibilities
Upstream Manufacturing Operations
* Independently execute media and buffer preparation activities.
* Perform cell culture expansion, vial thaw, seed train operations, and production-scale bioreactor processing.
* Operate and monitor fed-batch and perfusion bioreactor systems.
* Execute harvest, filtration, and process transfer operations.
* Troubleshoot manufacturing and equipment issues within established procedures.
In-Process Monitoring
* Perform routine process monitoring and data review.
* Operate analytical equipment including:
o Cedex Cell Analyzer
o Blood Gas Analyzer (BGA)
o Osmometer
o pH and conductivity meters
Aseptic Processing & Compliance
* Perform aseptic operations in classified environments.
* Maintain GMP-compliant documentation.
* Participate in deviation investigations and root cause assessments.
* Support audit preparation and inspection activities.
Training & Continuous Improvement
* Train and mentor Associate I personnel.
* Assist with SOP revisions and manufacturing documentation updates.
* Participate in process improvement and operational excellence initiatives.
* Support technology transfer and manufacturing readiness activities.
Qualifications:
Education & Experience
* Bachelor’s degree in Biotechnology, Biochemistry, Chemical Engineering, Life Sciences, or a related discipline with 3-5 years of relevant biopharmaceutical manufacturing experience.
* High School Diploma/GED with 6+ years of relevant experience may be considered.
Required Skills
* Strong understanding of mammalian cell culture and upstream processing.
* Experience operating bioreactors and associated equipment.
* Knowledge of GMP manufacturing requirements.
* Strong analytical and troubleshooting skills.
* Effective communication and team collaboration abilities.
Preferred Skills
* Experience with:
o Single-use bioreactor systems
o Perfusion technologies
o Cell culture analytics
o Process troubleshooting
o Technology transfer activities
Physical Requirements
* Ability to stand for extended periods.
* Ability to bend, reach, and lift up to 50 pounds.
* Ability to work in cleanroom environments while wearing required PPE.