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≈ $87k – $241k per year (Estimated)
Location
In office (South San Francisco)
Visa
H-1B filings in 12 months: 15 · green card filings: 5

Confirmed on the employer's own hiring board on Nov 1, 2026. First seen by Alion on Oct 29, 2026. Twist Bioscience scores B on the Alion truth index.

Overview
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Twist Bioscience is a synthetic biology company headquartered in South San Francisco, California that manufactures synthetic DNA on a silicon-based platform. Founded in 2013 and listed on Nasdaq, it sells genes, oligo pools, NGS target enrichment panels and library preparation kits, variant libraries and antibody discovery services to researchers in pharma, biotech, diagnostics and academia, with production in South San Francisco and Wilsonville, Oregon and teams in Quincy, Massachusetts, Carlsbad and Asia. It hires manufacturing associates, automation and systems engineers, scientists, bioinformatics specialists, and sales and business development staff.

We are looking for motivated, enthusiastic individuals to join our Twist Bioscience Operations Team in South San Francisco. The Manufacturing Associate, NGS TE will perform basic molecular biology workflows in a highly automated, high-throughput manner and will be responsible for the manufacture of variety of custom oligonucleotide products. The ideal candidate will be able to work independently, be very neat and organized, have the ability to follow established SOPs and complete manufacturing batch records to contribute to the daily production schedule. 

The ideal candidate will be driven and will do what it takes to keep manufacturing on track in a fast paced start-up environment.  The Manufacturing Associate will be responsible for the production of custom gene based products and/or various intermediates according to established SOPs and complete manufacturing batch records to contribute to the daily production schedule.  They will uphold standards as defined by the manufacturing process, work on continuous improvement and have good time management resulting in efficiency, and work in a safe manner.

Available Shifts:

2B: Wednesday-Friday, Alternating Saturday(7:00pm-7:30am)

Roles and Responsibilities include but are not limited to:

  • Manufacture high quality custom oligo containing products in a high throughput MFG lab according to established SOPs.
  • Operation of robotic laboratory equipment and traditional lab equipment (bioanalyzers, centrifuges, sealers, thermocyclers, spectrometers, HPLCs, Next Gen Sequencing etc.)
  • Daily use of traditional molecular biology processes and techniques especially PCR, DNA quantitation and handling, DNA purification
  • Maintaining thorough, accurate and detailed documentation of all work produced in batch records, databases or other acceptable formats  including problems and deviations
  • Updating and writing work instructions and documentation
  • Ability to work independently and in a safe manner
  • Attention to details for process consistency
  • Documentation, troubleshooting and addressing process deviations
  • Packaging products
  • Ability to work in an ISO, GMP, LEAN manufacturing environment and follow the lean manufacturing concepts
  • Daily completion of assigned tasks to keep MFG on track

Required for all levels:

  • Excellent written and verbal skills
  • Detail oriented
  • Good computer skills and comfort in using computers for all aspects of MFG, experience with Excel and Word, Jira/Confluence, web-based or similar programs

Typical Working Conditions are:

  • Team based laboratory environment.
  • Working in controlled laboratory environment
  • Must be able to stand for long periods of time while performing duties.
  • Must be able to work safely with chemicals and hazardous materials.
  • Must be able to lift up to 20 lbs.
  • Must be able to work outside of regular work hours/ work a flexible shift as needed

About Twist Bioscience

Twist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.

At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.

Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.

San Francisco applicants: Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records.

The base cash compensation for this California-based role is below. In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package. Final compensationamounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above. Compensationmay be different in other locations.

San Francisco Bay Area Pay Range

$21—$25 USD

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