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Salary
≈ $86k – $155k per year (Estimated)
Location
In office (Vancouver)
Seniority
Staff · 8+ years exp
Employment
Full-Time

Confirmed on the employer's own hiring board on Oct 27, 2026. First seen by Alion on Jul 14, 2026.

Overview
Company
Impact
Profile match
Zymeworks is a biotechnology company founded in Vancouver in 2003. It designs multifunctional antibody therapeutics using its own computational protein engineering platform. The company is listed on Nasdaq and partners with large pharmaceutical firms.

Company Description

Zymeworks is a global biotechnology company managing a portfolio of licensed healthcare assets and developing a diverse pipeline of novel, multifunctional biotherapeutics to improve the standard of care for difficult-to-treat diseases, including cancer, inflammation, and autoimmune disease. The Company’s asset and royalty aggregation strategy focuses on optimizing positive future cash flows from an emerging portfolio of licensed products such as Ziihera® (zanidatamab-hrii) and other licensed products and product candidates such as pasritamig. In addition, Zymeworks is also building a portfolio of healthcare assets that can generate strong cash flows, while supporting the early-stage development of innovative medicines. We are a global company headquartered in Vancouver BC, with operations in Bellevue WA, Dublin IRE, and Singapore.

Why Work With Us

Nothing is more critical to our success than the quality of our team. The work we do is meaningful and impactful - we care about each other as well as the patients we serve. We offer challenging career opportunities, competitive benefits and an environment that recognizes and rewards performance.

This role will be located in Vancouver and is hybrid with a minimum of 3 days per week onsite.

As the Lead Business Solutions Engineer, you are a hands-on technical lead for all enterprise systems and integrations that serve General & Administrative functions (such as Finance, HR and Legal). You ensure operational and project work is completed according to the business’s acceptance criteria, industry best practices and the Software Development Lifecycle (SDLC) regardless of whether you or an external consultant does the hands-on work. You are a self-sufficient, responsible and skilled custodian for our G&A systems and integrations who understands the value of well-designed processes and documentation. You are a capable technical firefighter and root cause analysis comes naturally to you. You have experience with SOX ITGCs and audits. You build trust and relationships with your team and business stakeholders by engaging with them regularly and you help them understand scope, cross functional business impact and cost, while minimizing technical debt. You approach risk management with transparency and are proactive in proposing mitigation options.

What You'll Do

  • Own, configure, script, create workflows, and administer core G&A enterprise applications including NetSuite, Coupa (P2P), HRIS system, and others.
  • Develop and drive the roadmap for optimization, automation, and tech debt reduction.
  • Effectively communicate business impact and associated risks of technical issues.
  • Design, build, and maintain system integrations between NetSuite, P2P applications, payroll, equity, and other internal platforms using middleware and ETL tools (Workato).
  • Establish and uphold SDLC standards, ensuring test cases are written, and UAT results are documented.
  • Create and maintain role-based permissions, reporting, and system enhancements within NetSuite and related applications.
  • Lead resolution of complex applications and integration issues, performing root cause analysis and corrective actions across systems and vendors.
  • Plan and execute system upgrades, patches, releases, and regression testing.
  • Establish and maintain technical documentation, design decision logs, data flows, and system architecture diagrams.
  • Facilitate workshops for design decisions, obtaining requirements, and training the business.
  • Partner with business and IT leaders to ensure technology changes are effectively governed, communicated and adopted.
  • Provide work estimates and assistswith work prioritization.
  • Support SOX ITGC controls related to financial systems, including access management, change management, and audit readiness.
  • Partner with IT and G&A leadership to translate operational requirements into scalable technical solutions.
  • Support data extraction, transformation, and loading (ETL) processes for reporting and downstream systems.
  • Provide technical oversight of third-party vendors and system integrators and holds them accountable to delivery standards, SLAs, and contractual commitments.
  • Create, configure and maintain MCP connectors and other AI related tools.

What You'll Bring

  • Bachelor of Computer Science, Business Administration, Accounting, or equivalent experience.
  • 8+ years of hands-on systems engineering experience in NetSuite, middleware and systems integrations.
  • 3+ years supporting Finance teams in NetSuite at a senior level.
  • 2+ years solution architecture experience or equivalent, including documentation, leading design decision workshops and creating diagrams.
  • Experience managing vendors.
  • Experience designing integrations across enterprise platforms.
  • Experience proposing new business solution options based on problem statements.
  • Experience with SOX ITGCs within ERP environments and participating in yearly audits.
  • Experience using Atlassian, Lucid and Sharepoint.
  • Experience using InvGate or other similar ticketing system preferred.
  • Demonstrated SDLC understanding and experience.
  • Demonstrated NetSuite scripting, workflow, configuration, QA, and system administration skills.
  • Demonstrated understanding of Finance, including financial system architecture, data structures, finance related concepts, processes and rules.
  • Demonstrated ability to apply change management principles to support successful technology adoption and minimize business disruption.
  • Able to troubleshoot systems and data issues independently.
  • Able to provide work estimates despite ambiguity.
  • Thrives in high-growth, high-change environments where systems must scale quickly.
  • Produces clear documentation and has strong technical communication skills.

Total Rewards

We offer a comprehensive total rewards package, which includes competitive salaries, generous benefits, an outstanding work environment, and excellent opportunities for professional growth. We regularly benchmark our compensation against leading biotechnology companies in our geographies.

The base salary range displayed on each job posting reflects the minimum and maximum target for new hire salaries for the position in the location for which the job is posted and does not include bonus, equity, or benefits. Within the range, individual pay is determined by a variety of factors and the salary offered may vary depending on the successful candidate’s location and qualifications (including, but not limited to, job-related knowledge, education, training, skills, and experience).

Our total rewards package that includes:

  • Industry leading vacation and paid time off
  • Exceptional medical, dental and vision benefits by country
  • Zymelife health and wellness benefits
  • Matching RRSP / 401K / Pension program
  • Employee Share Purchase Program
  • Employee Equity Program
  • Paid time off to volunteer in your community

This role is not eligible for relocation or immigration support.

All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin or disability.

NOTE TO AGENCIES: Zymeworks values our relationships with our recruiting partners. We only accept resumes from those partners who have been contracted with us. Zymeworks is not responsible for any fees related to resumes that are unsolicited or are received without contract.

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