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Salary
≈ $51k – $110k per year (Estimated)
Location
Hybrid (Lisbon, Portugal)
Seniority
Staff · 8+ years exp
Employment
Full-Time

Confirmed on the employer's own hiring board on Oct 18, 2026. First seen by Alion on Jul 7, 2026. Amgen scores B on the Alion truth index.

Overview
Company
Impact
Profile match
Amgen is an American biotechnology company founded in Thousand Oaks in 1980 that became one of the first firms to turn recombinant protein research into large commercial medicines. Its history rests on Epogen and Neupogen, and its current portfolio spans bone health with Prolia and Evenity, inflammation with Otezla and Tezspire, cardiovascular disease with Repatha, oncology including the bispecific antibody Blincyto, and a biosimilars business built on its own manufacturing capacity. The company is listed on Nasdaq, is a component of the Dow Jones Industrial Average, and expanded further into rare disease through its acquisition of Horizon Therapeutics.

Career Category

Information Systems

Job Description

Join our team at AMGENCapability Center Portugal, the #1 company in Best Workplaces™ (201-500 employees'category) in Portugal in 2024 by the Great Place to Work Institute. With over 500talented individuals from more than 40nationalities, our Lisbon center thrives at the intersection of innovation, excellence, and inspiration.This is your opportunity to explore the future of healthcare through technology and digital innovation, supporting our mission To Serve Patients.

SPECIALIST SOFTWARE ENGINEER - AppliedAI

At AMGEN, Technology isn’t just a support function-it’s a catalyst for discovery, transformation, and real-world impact. Here, your ideas fuel innovation that improves and saves lives of patients in dire need of our medicines. Are you ready to do meaningful work that matters?

LIVE

WHAT YOU WILL DO

The Specialist Software Engineer role offers a unique opportunity to join a fun, innovative AppliedAI team within the AI & Data Science (AI&D) - Enterprise Automation organization at Amgen.

As a Specialist Software Engineer, you will be an integral member of the AppliedAI - Custom GPT Practice team, which empowers Amgen teams and staff members to build high-value, purpose-driven Custom GPTs through expert design and development support. You will play a key role in driving adoption of this program across multiple Amgen organizations by partnering with cross-functional teams and senior leaders. This role requires strong technical depth, adaptability, and the ability to operate effectively in a fast-evolving environment.

The primary responsibility of this role is to design, develop, and deploy secure, scalable, and intuitive AI agents and Custom GPTs on leading enterprise AI platforms and tools.

Let’s do this. Let’s change the world. In this vital role you will:

GenAI / AI Delivery

  • Design, develop, and deploy GenAI-powered agents using large language models (LLMs), embeddings, vector databases, RAG frameworks, and prompt engineering.

  • Develop, test, and deploy Custom GPTs using the ChatGPT Enterprise UI for multiple functional teams across Amgen.

Collaboration & Enablement

  • Partner closely with functional teams, product owners, data engineers, platform teams, DevOps, and business SMEs to translate business requirements into reliable, production-grade solutions.

  • Produce clear technical design documentation, runbooks, and handover materials to support operational sustainability.

  • Mentor engineers and provide technical leadership to accelerate GenAI adoption across the enterprise.

  • Drive platform adoption through best practices, reusable patterns, and shared assets, including agent templates, prompt patterns, Databricks notebooks, and n8n workflows.

  • Implement Model Context Protocols (MCPs) using APIs, SDKs, and orchestration tools to enable seamless integration with GenAI-powered agents.

  • Build integration layers and event-driven orchestrations using n8n (webhooks, nodes, APIs) to connect systems, trigger agent workflows, and implement human-in-the-loop processes.

  • Drive experimentation and innovation with new models, features, agents, and frameworks (e.g., OpenAI, Databricks, LangChain).

  • Ensure solutions comply with Amgen’s data privacy, security, and regulatory standards.

  • Stay current with advancements in Generative AI, LLMs, and RAG methodologies to continuously improve platform capabilities.

WIN

WHAT WE EXPECT OF YOU

We are all different, yet we all use our unique contributions to serve patients. The tech professional we seek is a creative problem-solver and a team player with these qualifications:

Basic Qualifications

  • Master’s degree with 5+ years of experience in Computer Science, IT, or a related field, OR

  • Bachelor’s degree with 8+ years of experience in Computer Science, IT, or a related field.

  • Must-Have Skills

  • Ability to work effectively with global, distributed teams using Scaled Agile methodologies.

  • 5+ years of professional experience in software development and system design.

  • 3+ years of hands-on experience building and deploying Generative AI applications or Custom GPTs in production, centered around OpenAI (preferred), Claude, or Gemini.

Soft Skills

  • Strong verbal and written communication skills.

  • High degree of initiative and self-motivation, with a servant-leadership mindset.

  • Ability to work under minimal supervision while delivering high-quality outcomes.

  • Excellent analytical, gap, and fit-assessment skills.

  • Ability to manage multiple priorities successfully.

  • Team-oriented, with a strong focus on achieving shared goals.

Good-to-Have Skills

  • Experience working with Power Automate, Tableau, JIRA, and Smartsheet.

  • Familiarity with GxP environments and systems validation.

  • Experience working in regulated industries such as biotech or healthcare.

  • Hands-on experience designing and building cloud-native solutions, preferably on AWS (e.g., Bedrock, Lambda, SageMaker).

  • Hands-on experience with vector databases, embedding models, and retrieval pipelines.

  • Strong programming skills in Python, with familiarity in GenAI libraries such as Transformers, LangChain, and Hugging Face.

  • Experience with LLM fine-tuning, prompt engineering, and model evaluation.

  • Experience designing secure integrations using API gateways and RESTful services.

  • Strong problem-solving skills and the ability to perform effectively in a fast-paced environment.

THRIVE

WHAT YOU CAN EXPECT OF US

As we work to develop treatments that take care of others, we also care deeply for our teammates’ well-being and growth.

  • Work That Matters - Build tech that accelerates scientific breakthroughs and helps patients worldwide.

  • Modern Tech Stack - Cloud-first, automation-focused, AI-powered.

  • Global Scale, Agile Mindset - Collaborate across continents while working in nimble, high-impact teams.

  • Continuous Learning - Access to certifications, trainings, mentorship, and career mobility.

  • AMGENTotal Rewards Plan - Comprehensive benefits in healthcare, finance, and well-being.

  • Flexibility - Hybrid work model with time split between our Lisbon office and remote work.

APPLY NOW

Join us in our mission to serve patients.

CAREERS.AMGEN.COM

EQUAL OPPORTUNITY STATEMENT

AMGEN is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided a reasonable accommodation to participate in the job application or interview process, to perform crucial job functions, and to receive other benefits and privileges of employment. Please contact us to request an accommodation.

.

Salary Range

51,812.60 EUR - 70,099.40 EUR
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