Senior Manager, Brand Analytics & Forecasting

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.

Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).

Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way.

The Senior Manager, Brand Analytics and Forecasting support brand-level analytics and demand forecasting in support of Commercial brand teams. Reporting to the Director of Brand Analytics, this role builds and maintains short- and mid-range forecasts, tracks brand performance against key metrics, and partners with Commercial and Finance leadership to inform planning and investment decisions. The ideal candidate combines rigorous forecasting expertise with the business acumen to translate model output into clear, actionable narratives for senior leadership.

Role & Responsibilities

• Support patient-based and demand forecasting models for assigned brand(s), spanning in-line and long-range horizons.
• Apply and maintain robust forecasting methodology, including scenario planning, sensitivity analysis, and risk-adjusted forecasting.
• Partner with Commercial and Finance leadership on performance tracking, KPI dashboards, and business review analytics.
• Leverage patient-level analytics - line of therapy, patient journey, new vs. continuing patients, switching, persistence, and adherence - to uncover growth drivers, risks, and opportunities.
• Partner with cross-functional analytics & data team to understand latest on-ground intel and leverage the most relevant data sources to inform assumptions and forecast scenarios
• Support variance and root-cause analyses linking actual performance to forecast assumptions and executional drivers, and reconcile patient, sales, and audit perspectives into a single source of brand-performance truth.
• Manage forecasting vendors or consultants as needed, and mentor junior analysts supporting brand analytics.

Qualifications

Typical Degree & Years of Experience

• Bachelor's degree in a quantitative, business, or related field; advanced degree (MBA, MS) preferred.
• 6+ years of experience in pharmaceutical or biotech commercial analytics, including direct experience in brand analytics and/or forecasting.
• Experience with pharmaceutical demand and patient-based forecasting methodologies.
• Experience working with syndicated and patient-level data (e.g., IQVIA NPA/NSP, LAAD, DDD, Xponent), claims, and specialty pharmacy data.
• Hands-on proficiency in SQL and at least one statistical platform (SAS, R, or Python), plus data visualization tools such as Power BI or Tableau.

Preferred

• Experience supporting specialty or rare disease brands, ideally through a launch.
• Experience with hands on development of forecast and relevant analytics to track performance
• Experience with leadership presentation development
• Experience mentoring or managing junior analyst.

Skills & Competencies

• Strong quantitative and statistical forecasting skills, with attention to methodological rigor.
• Ability to translate forecast output into clear business narratives for commercial and finance leadership.
• Attention to detail balanced with a view toward the broader strategic picture.
• Effective cross-functional collaboration with brand, finance, and market access teams.

Madrigal’s Total Rewards strategy is based on a biotech industry peer group comparator and is inclusive of base pay, bonus and equity. Our equity offers meaningful opportunity allowing our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization.

All employees receive equity, which we believe reinforces our ownership culture. Base salary is determined by several factors including the candidate’s qualifications, skills, education, experience, business needs and market demands. As of the date of this posting, a good faith estimate of the current pay scale for this position, applicable to all candidates, is $158,000 - $193,000 per year. We comply with all applicable minimum wage laws.

All full-time employees receive equity, which reinforces our ownership culture and offers meaningful opportunity for our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization.

Full-time employees are also eligible for comprehensive benefits, including flexible paid time off, medical, dental, vision and life/disability insurance, and 401(k) offerings (i.e., traditional, Roth, and employer match) in accordance with applicable plans. We also offer additional voluntary benefits like supplemental life insurance, legal services, and other offerings. In addition, we offer mental health benefits through our Employee Assistance Program for employees and their family. The company also provides other benefits in accordance with applicable federal, state, and local laws.

We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance, please contact [email protected].

Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law.

Unsolicited resumes from agencies should not be forwarded to Madrigal. Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established.

Applications are being accepted on an ongoing basis and can be submitted through our Madrigal Careers site.

Please be aware that we have received reports of individuals misrepresenting themselves as Madrigal Pharmaceuticals’ Hiring Managers, seeking to engage with job candidates through fraudulent online advertisements or job posting sites. These unauthorized individuals are using Madrigal’s name and logo in an attempt to solicit up-front fees and obtain personal information from interested job candidates. Please know that Madrigal does not conduct interviews via text or in chat rooms; conduct interviews via Skype, RingCentral or solely via telephone; charge candidates an advance fee of any kind (e.g., fees for purchasing equipment); nor does it offer positions of employment without undergoing a thorough recruiting process.

Please also note that any correspondence with regard to employment would come from an authorized madrigalpharma.com email address or from an email address from one of our trusted search firm partners. We are aware that incorrect/fraudulent email addresses, with Madrigal misspelled, have been utilized in these most recent fraud attempts. If you receive unsolicited employment offers from people claiming to work for or on behalf of Madrigal, we recommend that you: do not respond to their questions; do not open any attachments; and do not click on any hyperlinks. Any questions regarding the legitimacy of job-related contacts can be directed to [email protected].