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Salary
$126k – $157k per year
Location
Remote (United States)
Seniority
Senior · 6+ years exp
Visa
H-1B filings in 12 months: 74 · for this role: 22 · green card filings: 31

Confirmed on the employer's own hiring board on Oct 28, 2026. First seen by Alion on Oct 26, 2026. Natera scores B on the Alion truth index.

Overview
Company
Impact
Profile match
Natera is an American diagnostics company founded in 2004 that built its business on cell-free DNA testing, analysing fragments of DNA circulating in blood to answer questions that previously required an invasive procedure. Its products span prenatal screening, carrier testing, organ transplant rejection monitoring and oncology, where its Signatera test detects residual cancer DNA after treatment and can indicate recurrence months before imaging would. Headquartered in Austin and listed on Nasdaq, its economics depend heavily on payer reimbursement decisions, which have historically been the difference between a test being widely used or barely used at all.

POSITION SUMMARY:

Are you ready to make a real impact on people's lives and be a part of a rapidly-growing team? Natera is seeking a Senior Software Engineer to help design, develop, and maintain our web portal application serving providers. As a member of our engineering team, you will play a key role in improving the user experience and functionality, ultimately helping to positively impact patient outcomes. Join us in our mission to change the way cancer is managed, and be a part of a team of dedicated professionals who are passionate about making a difference.

Senior Software Engineer - Portal Application is responsible for the design, development, and maintenance of microservices for our provider-facing web portal. The role requires working with a mix of modern and legacy technologies in a rapidly changing environment and the ability to adapt quickly to new technologies and systems. Together with the talented Engineering Team, Product Managers and Designers, you will work on new and exciting experiences for our customers.

PRIMARY RESPONSIBILITIES

  • Participate in design and technical implementation decisions and help guide key stakeholders on the team, such as product managers, UI/UX designers, to ensure that design and technical decisions meet a high standard of excellence.
  • Work closely with Product Managers to gather requirements, walk through the design with stakeholders, and support software all the way from initial ideation to release, operation, and maintenance.
  • Participate in designing, building, and maintaining highly available systems to support our business applications, users, providers, and patients.
  • Perform code reviews and mentor the development team with best practices.
  • Continue improving process and procedure and evangelizing best practices.
  • Support QA activities in conjunction with our QA engineering teams.
  • Be a contributing team member to the end-to-end execution of compliance initiatives.
  • This role works with PHI on a regular basis both in paper and electronic form and have access to various technologies to access PHI (paper and electronic) in order to perform the job. 
  • Must complete training relating to HIPAA/PHI privacy, General Policies and Procedure Compliance training and security training as soon as possible but not later than the first 30 days of hire.
  • Must maintain a current status on Natera training requirements.

QUALIFICATIONS

  • BS degree in computer science, comparable program, or equivalent.
  • 6+ years of overall software development experience, preferably secure, scalable web applications with NodeJS, TypeScript, React, and other web technologies.
  • Experience with front-end development.
  • Experience with software development lifecycle process from build, software configuration, change control, release and deployment activities.
  • Extensive knowledge and experience with Test-Driven Development and/or Domain-Driven Development Experience with service-oriented and microservice architecture.
  • Experience building, maintaining, troubleshooting, and expanding software within the AWS ecosystem: EC2, ECS, Lambda, Step Functions, SQS, SNS, S3, etc.
  • Experience with GraphQL and REST API design and event-driven architecture using distributed event stores (such as Kafka).
  • Experience with micro-service enterprise architecture, cross-platform integration, and building scalable applications in heterogeneous environments.
  • Strong relational database skills including database design and optimization.
  • Demonstrated teamwork skills with a solid analytical background.
  • Excellent organizational, communication, presentation, and facilitation skills.

KNOWLEDGE, SKILLS, AND ABILITIES

  • Linux Fundamentals
  • Object Oriented Programming
  • Relational Database and SQL Programming, prefer MySQL or PostgreSQL
  • JavaScript Programming
  • Java Programming is nice to have
  • SQL and NoSQL database experience including MySQL, ElasticSearch, and DynamoDB
  • AWS Services, such as EC2, Lambdas, Step Functions, SQS, S3, and SNS
  • Build infrastructure as code with Terraform and Cloud Formation
  • Docker or container-oriented technologies
  • GraphQL and REST APIS
  • Event-Driven Microservice Architecture
  • Experience with front-end technologies such as NextJS, React, Sass, Material, HTML, CSS, Javascript, NodeJS.
  • CI / CD (Gitlab)
  • Quality Assurance Mindset

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.

Remote USA

$125,600—$157,000 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit www.natera.com.

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents. 

Link: https://www.natera.com/notice-of-data-collection-california-residents/

Please be advised that Natera will reach out to candidates with a @natera.com  email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

For more information:

- BBB announcement on job scams  

- FBI Cyber Crime resource page  

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