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Location
In office (Hopkinton, United States)
Seniority
Senior · 7+ years exp
Visa
H-1B filings in 12 months: 3
Employment
Full-Time

Confirmed on the employer's own hiring board on Nov 9, 2026. First seen by Alion on Nov 4, 2026. Repligen scores B on the Alion truth index.

Overview
Company
Impact
Profile match
Repligen is an American life sciences company that develops and manufactures bioprocessing products used in the production of biologic drugs, including filtration systems, chromatography columns and resins, protein A ligands, fluid management and process analytics tools. It supplies biopharmaceutical manufacturers and contract development and manufacturing organisations worldwide from sites in the United States, Europe and Asia. The company is headquartered in Waltham, Massachusetts, United States.
We are currently hiring a Sr. Facilities Mechanic for our Hopkinton site. The Sr. Facilities Mechanic position is responsible for performing highly diversified duties to install, troubleshoot, repair, and maintain production and facility equipment according to safety and compliance and to ensure continued operational sustainability of facilities. This position has a high requirement is responsible for start-up of equipment, preventive maintenance, changeovers, repairs, basic/routine equipment maintenance and optimization while developing and following all safety measures. Lead projects, schedule repairs and maintenance to adhere to manufacturing schedule. Draft and execute qualification protocols and SOPs. Update and create drawings and make recommendations for continuous improvement.

This role is expected to model our Leadership Behaviors-Integrity & Compliance, Customer Focus, Collaboration, Courage, Team Empowerment, and Accountability & Results-in all aspects of work.

Responsibilities:

  • Team Leadership & Project Management: Lead maintenance technicians through routine preventive maintenance (PMs), facility projects, new equipment rollouts, and standard operating procedures.
  • Equipment Maintenance & Troubleshooting: Perform routine and emergency maintenance, troubleshooting, and repairs across mechanical, electrical, pneumatic, hydraulic, plumbing, and calibration systems. Diagnoses issues, replace parts, test systems, and make adjustments to return equipment to safe operational status.
  • Facilities & BMS Monitoring: Manage the Building Management System (BMS) and conduct routine rounds to monitor facility operations and proactively identify equipment faults.
  • Technical & Electrical Support: Utilize strong mechanical and electrical aptitude to support electrical vendors and perform simple machinist duties, including setting up equipment to precise specifications.
  • Documentation & Manuals: Read and interpret equipment manuals, engineering drawings, and work orders to perform service and maintain detailed compliance logs.
  • PM & Calibration Development: Collaborate with Facilities and Engineering teams to establish PM/calibration frequencies and develop Preventive Maintenance, Calibration, and Equipment Operation procedures.
  • Assembly & Capital Projects: Assemble new or modified components, systems, and assemblies while supervising external vendors and contractors during major repairs, services, and facility shutdowns.
  • Quality & GxP Compliance: Support quality systems, audits, CAPA resolution, deviations, and GMP investigations. Drive continuous improvement for Standard Operating Procedures (SOPs) and GxP compliance.
  • Cross-Functional Collaboration & SME Leadership: Serve as a Subject Matter Expert (SME) on critical systems and spare parts assessments. Partner with cross-functional teams, escalate downtime to area owners, and ensure all scheduled targets are met safely and efficiently.

Qualifications & Technical Skills

  • Technical & Electro-Mechanical Aptitude: 7+ years of advanced experience in electro-mechanical troubleshooting, maintenance, and repair across AC/DC control systems, drives, angle drive motors, gearboxes, encoders, and proximity switches.
  • Manufacturing & Cleanroom Operations: Strong background in packaging and assembly line diagnostics, system upgrades, and operational optimization. Experience in ISO cleanroom environments and cleanroom utilities preferred.
  • Electrical Safety & Compliance: Familiarity with the National Electrical Code (NEC) and NFPA 70E electrical safety standards. Hands-on experience reading and interpreting P&IDs, electrical schematics, and mechanical drawings.
  • Software & Systems: Proficient with MS Office (Excel, Word) with familiarity in MS Project. CAD/SolidWorks and Computerized Maintenance Management Systems (CMMS) experience preferred.
  • Continuous Improvement & Quality: Familiarity with 5S/6S methodologies and Lean Manufacturing principles to drive process efficiency and workspace organization.
  • Soft Skills & Ownership: Self-starter with a strong sense of urgency, high organization, and systematic precision. Proven capability to act as a technical owner for critical manufacturing systems.

Education & Certification Requirements

  • Education: Degree in engineering discipline, completion of a recognized craft apprenticeship, or equivalent combination of education and hands-on industrial experience.
  • Experience: Minimum 7+ years of industrial maintenance experience in automated manufacturing, life sciences, or medical device environments.
  • Licensure / Certifications: Valid trade license (Electrical, HVAC, Plumbing, or PLC) or extensive equivalent experience in regulated life science/medical device manufacturing preferred. Universal EPA Refrigeration certification desirable.
  • Driver’s License & Availability: Valid driver's license, reliable transportation, and willingness to participate in an on-call rotation for emergency maintenance.

Physical Requirements

  • Physical Effort: Regularly required to stand, walk, bend, stoop, kneel, crouch, crawl, reach, and handle tools or equipment. Must be able to regularly lift and/or move up to 50 lbs.
  • Visual & Auditory: Specific vision abilities required include close vision, peripheral vision, and depth perception, along with clear hearing and speaking capabilities for site safety and team communication.

Our mission is to inspire advances in bioprocessing as a trusted partner in the production of biologic drugs that improve human health worldwide. Focused on cost and process efficiencies, we deliver innovative technologies and solutions that help set new standards in bioprocessing. The estimated base hourly range for this role, based in the United States of America is $35.66-48. Compensation decisions are dependent on several factors including, but not limited to an individual's qualifications, location, internal equity, and alignment with market data. Additionally, employees are eligible to participate in one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits such as paid time off, health/dental/vision, retirement benefits and flexible spending accounts. All compensation and benefits information will be confirmed in writing at the time of offer.

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