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Salary
$180k – $250k per year
Location
In office (San Francisco)
Employment
Full-Time

Confirmed on the employer's own hiring board on Oct 30, 2026. First seen by Alion on Oct 30, 2026.

Overview
Company
Impact
Profile match
Physician-led health benefits for startups with 10+ employees. Replace PEO and fully insured plans with transparent pricing, better care, and lower costs.
Backed by Y Combinator

We're building the last healthcare company

In a world with AGI, only healthcare, entertainment, and compute will matter. Healthcare is both the most meaningful and the most broken. Premiums climb 15% a year, physicians are burning out, and patients have lost trust, even as new medicines such as immunotherapy & synthetic proteins make it possible to efficiently buy quality-adjusted life years (QALYs). An insurance system built to pay for catastrophe, on the premise that no one can know who will get sick, cannot deliver the future of medicine; it's no surprise their biggest priority is finding out how to deny more care. Misalignment runs through every layer. We believe it can only be fixed by owning all of healthcare. Medical superintelligence makes that possible for the first time. Prescience is a vertically integrated system where risk pricing, care delivery, and disease anticipation are redesigned from scratch around AI that administers the whole stack. We train AI systems to operate, insure, and deliver healthcare for new health plans. We are already seeing rapid organic adoption from employers, patients, and providers. Prescience is the only healthcare company where every gain in AI capability and every life added to our network compounds our advantage. We see a future where buying health insurance is replaced by buying health outcomes from Prescience.

About Us

Prescience is a seed-stage company, most recently valued at $150M. It is backed by investors such as Bain Capital Ventures, Conviction, Pear VC, Greycroft, and Y Combinator. You will join the founding team and will work directly with the two brothers: Rishab and Aditya Jain. They have been on the frontier of AI research together since 2014. Aditya earned his M.D. from Harvard Medical School and forwent a career in medicine to build Prescience. He was also a researcher at the Broad Institute. Rishab was named one of TIME’s 25 Most Influential Teens at 13, won the Regeneron ISEF top award, and led two companies to successful acquisition before leaving Harvard to co-found Prescience. We are building a founding team of world-class talent.

If you’re excited to solve some of the world’s biggest problems and build AI systems to power prescient healthcare, apply to join us.

The Role

Our number one priority is scaling to market demand. We are looking for individuals who are high horsepower, high throughput, and extremely resourceful to help us increase capacity and grow. We move fast and need to move faster.

The models will do most of the work; your job is to build everything that lets them: the data, harnesses and tools, and infra. This is a founding role with an unprecedented level of ownership and agency. You will pick problems, own them end to end, and ship to production.

Skills We’re Looking For

We’re hiring two, high-agency, full-stack founding engineers. Exceptional candidates demonstrate skills in:

  • Full-stack development. Comfortability and deep expertise with using TypeScript across the stack: React, modern backend frameworks, and relational database.
  • Product. Shipped work that shows real taste when it comes to layout, hierarchy, and user experience.
  • Web automation. Playwright, Puppeteer, Selenium, or computer-use agents. Tell us about systems you've automated or hacked in the past.
  • LLMs in production. Hands-on with structured extraction, classification, and agentic workflows; a practical grasp of prompt design, structured outputs, retrieval, and fine-tuning.
  • Integration-heavy systems. Stitched together many external APIs and designed clean ones of your own.
  • Scripting - a bias toward scripting and automating your way out of repetitive work.

In a single month at Prescience you'll route millions of real dollars over banking rails, build computer-use and LLM agents that extract and automate online systems, scrape terabytes of messy data, integrate dozens of APIs together, and ship a user experience that a patient uses to get care. You'll also get to grow in ML capabilities working alongside our research team.

What we offer

  • Small, highly selective team where research and product move together; code reaches deployment same day
  • A generous cash base.
  • Founding-team equity.
  • Compute is not a constraint: GPUs and unconstrained token spend.
  • The best health insurance you've ever had.
  • Uber vouchers, DoorDash, Fitbits
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